A Severe Case of Wheat-Dependent Exercise-Induced Anaphylaxis in Adulthood
DOI:
https://doi.org/10.3889/oamjms.2014.088Keywords:
wheat-dependent exercise-induced anaphylaxis, food-dependent exercise-induced anaphylaxis, skin prick test, steroidal anti-inflammatory drugs, exercise induce anaphylaxis.Abstract
Food-dependent exercise-induced anaphylaxis (FDEIA), is a severe form of allergy for which the ingestion of a specific food, usually before physical exercise induces symptoms of anaphylaxis. Patients typically have IgE antibodies to the food that triggers the reactions; however, the symptoms appear only if the co-factors act together. The most common reported cause of these reactions seems to be wheat. In some cases FDEIA is displayed even when the food is eaten immediately after exercise, showing that in FDEIA, not the sequence but rather the coincidence of triggering factors use, is of crucial importance. The risk to develop anaphylaxis in these patients depends on the presence and, in some cases, on the amount of cofactors of anaphylaxis. There are lots of evidences about the role of NSAIDs as cofactors of anaphylaxis.Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Beaudouin E, Renaudin JM, Morisset M, Codreanu F, Kanny G, Moneret-Vautrin DA. Food-dependent exercise-induced anaphylaxis--update and current data. Eur Ann Allergy Clin Immunol. 2006;38(2):45-51.
Inomata N. Wheat allergy. Curr Opin Allergy Clin Immunol. 2009; 9 (3):238-43. DOI: https://doi.org/10.1097/ACI.0b013e32832aa5bc
Matsuo H, Morimoto K, Akaki T, Kaneko S, Kusatake K, Kuroda T, Niihara H, Hide M, Morita E. Exercise and aspirin increase levels of circulating gliadin peptides in patients with wheat-dependent exercise-induced anaphylaxis. Clin Exp Allergy. 2005; 35 (4):461-6. DOI: https://doi.org/10.1111/j.1365-2222.2005.02213.x
Morita E, Matsuo H, Chinuki Y, Takahashi H, Dahlström J, Tanaka A. Food-dependent exercise-induced anaphylaxis -importance of omega-5 gliadin and HMW-glutenin as causative antigens for wheat-dependent exercise-induced anaphylaxis. Allergol Int. 2009;58(4):493-8. DOI: https://doi.org/10.2332/allergolint.09-RAI-0125
Wölbing F, Biedermann T. Anaphylaxis: opportunities of stratified medicine for diagnosis and risk assessment. Allergy. 2013;68(12):1499-508. DOI: https://doi.org/10.1111/all.12322
Palosuo K, Alenius H, Varjonen E, Koivuluhta M, Mikkola J, Keskinen H, Kalkkinen N, Reunala T. A novel wheat gliadin as a cause of exercise-induced anaphylaxis. J Allergy Clin Immunol. 1999;103 (5 Pt 1):912-7. DOI: https://doi.org/10.1016/S0091-6749(99)70438-0
Takahashi H, Matsuo H, Chinuki Y, Kohno K, Tanaka A, Maruyama N, Morita E. Recombinant high molecular weight-glutenin subunit-specific IgE detection is useful in identifying wheat-dependent exercise-induced anaphylaxis complementary to recombinant omega-5 gliadin-specific IgE test. Clin Exp Allergy. 2012; 42 (8):1293-8. DOI: https://doi.org/10.1111/j.1365-2222.2012.04039.x
Harada S, Horikawa T, Ashida M, Kamo T, Nishioka E, Ichihashi M. Aspirin enhances the induction of type I allergic symptoms when combined with food and exercise in patients with food-dependent exercise-induced anaphylaxis. Br J Dermatol. 2001; 145 (2):336-9. DOI: https://doi.org/10.1046/j.1365-2133.2001.04329.x
Chinuki Y, Morita E. Wheat-dependent exercise-induced anaphylaxis sensitized with hydrolyzed wheat protein in soap. Allergol Int. 2012; 61(4):529-37. DOI: https://doi.org/10.2332/allergolint.12-RAI-0494
Wojciech Barg, Wojciech Medrala, Anna Wolanczyk-Medrala. Exercise-Induced Anaphylaxis: An Update on Diagnosis and Treatment. Curr Allergy Asthma. 2011; 11(1): 45–51. DOI: https://doi.org/10.1007/s11882-010-0150-y
Wölbing F, Fischer J, Köberle M, Kaesler S, Biedermann T. About the role and underlying mechanisms of cofactors in anaphylaxis. Allergy. 2013;68(9):1085-92. DOI: https://doi.org/10.1111/all.12193
Robson-Ansley P, Toit GD. Pathophysiology, diagnosis and management of exercise-induced anaphylaxis. Curr Opin Allergy Clin Immunol. 2010; 10 (4):312-7. DOI: https://doi.org/10.1097/ACI.0b013e32833b9bb0
Palosuo K, Varjonen E, Nurkkala J, Kalkkinen N, Harvima R, Reunala T, Alenius H. Transglutaminase-mediated cross-linking of a peptic fraction of omega-5 gliadin enhances IgE reactivity in wheat-dependent, exercise-induced anaphylaxis. J Allergy Clin Immunol. 2003;111 (6):1386-92. DOI: https://doi.org/10.1067/mai.2003.1498
Park HJ, Kim JH, Kim JE, Jin HJ, Choi GS, Ye YM, Park HS. Diagnostic value of the serum-specific IgE ratio of ω-5 gliadin to wheat in adult patients with wheat-induced anaphylaxis. Int Arch Allergy Immunol. 2012;157(2):147-50. DOI: https://doi.org/10.1159/000327549
Lee JY, Yoon S, Ye YM, Hur GY, Kim S, Park HS. Gliadin-specific IgE in wheat-dependent exercise-induced anaphylaxis. Allergy Asthma Proc. 2008; 29 (6):614-21. DOI: https://doi.org/10.2500/aap.2008.29.3175
Yokooji T, Kurihara S, Murakami T, Chinuki Y, Takahashi H, Morita E, Harada S, Ishii K, Hiragun M, Hide M, Matsuo H. Characterization of causative allergens for wheat-dependent exercise-induced anaphylaxis sensitized with hydrolyzed wheat proteins in facial soap. Allergol Int. 2013; 62 (4):435-45. DOI: https://doi.org/10.2332/allergolint.13-OA-0561
Downloads
Published
How to Cite
Issue
Section
License
http://creativecommons.org/licenses/by-nc/4.0