25-Hydroxy Vitamin D, Adiponectin Levels and Cardiometabolic Risk Factors in a Sample of Obese Children

Authors

  • Nayera E. Hassan Biological Anthropology Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Sahar A. El-Masry Biological Anthropology Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Rokia A. El Banna Biological Anthropology Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Mones M. Abu Shady Child Health Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Muhammad Al-Tohamy Biological Anthropology Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Manal Mouhamed Ali Biological Anthropology Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Mehrevan M. Abd El-Moniem Medical Biochemistry Department, Medical Research Division, National Research Centre, Dokki, Giza
  • Mona Anwar Children with Special Needs Department, Medical Research Division, National Research Centre, Dokki, Giza

DOI:

https://doi.org/10.3889/oamjms.2014.101

Keywords:

25-Hydroxy vitamin D, adiponectin, lipid profile, blood pressure, children.

Abstract

BACKGROUND: Association between vitamin D, adiponectin and obesity is a matter of debate, as they play important role in linking obesity with different cardio metabolic risk factors.

AIM: Evaluation of association between metabolic risk factors with both adiponectin and 25-Hydroxy vitamin D [25(OH) D] levels and that between adiponectin and [25(OH) D] among obese Egyptian children.

SUBJECTS AND METHODS: This case-control cross sectional study consisted of 65 obese and 30 healthy children, aged 8-11 years. 25(OH) D, serum adiponectin, total cholesterol, triglycerides, high-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol were measured.

RESULTS: The mean 25(OH)D and adiponectin levels in the obese were lower than that in control group (ð‘ƒ<0.000). 25(OH)D were inversely correlated with body mass index, triglyceride, total cholesterol and LDL-cholesterol. While adiponectin level were inversely correlated with systolic and diastolic blood pressure, and positively correlated with high-density lipoprotein-cholesterol. However, there is no relation between 25(OH) D and adiponectin levels among obese children and total sample.

CONCLUSION: Inspite of strong association between vitamin D and adiponectin levels with metabolic risk factors and obesity, there is no relation between 25(OH)D and adiponectin levels. In obese children, There are significant negative correlations between 25(OH)D with lipid profile, and between adiponectin levels with blood pressure.

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Published

2014-12-15

How to Cite

1.
Hassan NE, El-Masry SA, El Banna RA, Abu Shady MM, Al-Tohamy M, Mouhamed Ali M, Abd El-Moniem MM, Anwar M. 25-Hydroxy Vitamin D, Adiponectin Levels and Cardiometabolic Risk Factors in a Sample of Obese Children. Open Access Maced J Med Sci [Internet]. 2014 Dec. 15 [cited 2024 Mar. 28];2(4):562-6. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2014.101

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Section

A - Basic Science

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