A Comparative Evaluation of Low-Level Laser and Topical Steroid Therapies for the Treatment of Erosive-Atrophic Lichen Planus
Keywords:low level laser therapy (LLLT), steroids, oral lichen planus (OLP), visual analogue scale
BACKGROUND: Oral lichen planus (OLP) is a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa, tongue, and gingivae. Erythema, erosions, and blisters may or may not be present. Several empirical therapies have been used in the treatment of (OLP).
OBJECTIVE: To evaluate the effect of low level laser therapy (LLLT) versus topical steroids for the treatment of erosive-atrophic lichen planus.
SUBJECTS AND METHODS: Twenty-four patients with erosive-atrophic (OLP) were categorized into two groups. In the first group patients were treated with 970nm diode laser irradiation, while, in the second group patients used topical corticosteroids (0.1% triamcinolone acetonide orabase). The gender, medical history and pain score were recorded. The pain score was measured before and after treatment by visual analogue scale (VAS).
RESULTS: Steroid-treated group (0.1% triamcinolone acetonide orabase) show reduced pain score than laser group.
CONCLUSION: Topical steroids are more effective than LLLT. LLLT may be used as an alternative treatment for symptomatic OLP when steroids are contraindicated.
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Dissemond J. Oral lichen planus: an overview. J Dermatolog Treat. 2004; 15:136-40.
Scully C, Beyli M, Ferreiro MC, Ficarra G, Gill Y, Griffiths M et al. Update on oral lichen planus: etiopathogenesis and management. Crit Rev Oral Biol Med. 1998; 9:86-122.
Sharma S, Saimbi CS, Koirola B. Erosive Oral lichen planus and its management: a case series. J Nepal Med Assoc. 2008; 47:86-90.
Dissemond J. Oral lichen planus: an overview. Dermatol Treat. 2004; 15(3):136-140.
Cerero R, Garcia-Pola MJ. Management of oral lichen planus. Med Oral. 2004; 9:124.
Carrozzo M, Gandolfo S. The management of oral lichen planus. Oral Dis. 1999; 5:196-205.
Vente C, Reich K, Rupprecht R. Erosive mucosal lichen planus: Response to topical treatment with Tacrolimus. Br J Dermatol. 1999; 140: 338-342.
Conrotto D, Carbone M, Carrozzo M, Arduino P, Broccoletti R, Pentenero M. Ciclosporine vs.clobetasol in the topical management of atrophic and erosive oral lichen planus: a double-blind, randomized controlled trial. Br J Dermatol. 2006; 154:139-145.
Little J, Falace D, Miller C. Dental management of medically compromised patient. 7thed. Philadelphia, 2007:p.236-245.
Voute AB, Schulten, EA, Langendijk PN. Fluocinonide in an adhesive base for treatment of oral lichen planus. Oral Surg.Oral Med.Oral Pathol. 1993; 75:181-185.
Passeron T, Zakaria W, Ostovari N, Mantoux F, Lacour JP, Ortonne JP. Treatment of erosive oral lichen planus by the 308 nm excimer laser. Lasers Surg Med. 2004; 34:205.
Cafaro A, Arduino PG, Massolini G, Romagnoli E, Broccoletti R. Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus: a prospective case series. Lasers Med Sci. 2014; 29:185-190.
Kramer IR, Lucas RB, Pindborg JJ, Sobin LH. WHO Collaborating Centre for Oral Precancerous Lesions: definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg Oral Med Oral Pathol. 1978; 46:518-539.
Brightman VJ. Red and white lesions of the oral mucosa.In: Burketâ€™s Oral Medicine and treatment. 11thEdition. Eds: Greenberg M.and Glick M, 2003.
Sharma S, Saimbi CS, Koirala B. Erosive oral lichen planus and its management: a case series. J Nepal Med Assoc. 2008; 47(170):86-90
Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom. Current controversies in oral lichen planus: report of an international consensus meeting.Part2.Clinical management and malignant transformation. Oral Surg Oral Med Pathol Oral Radiol Endod. 2005; 100:164-178.
Å¢Äƒranu T, EÅŸanu I, Grigorovici M, Toader M. Grinspanâ€™s Syndrome. Roman Oral Rehabilit. 2013; 5: 22-26.
Conrotto D, Carbone M, Carrozo M, Arduino P, Broccoletti R, Penetenero M. Ciclosporin vs. clobetasol in the topical management of atrophic and erosive oral lichen planus: a double-blind, randomized controlled trial. Br J Dermatol. 2006; 154:139-145.
Gonza-Moles MA, Scully C. Vesiculo-erosive oral mucosal disease-management with topical corticosteroids: fundamental principles and specific agentâ€™s available. J Dent Res. 2005; 84:294-301.
Xia J, Li C, Hong Y, Yang L, Huang Y. Short-term clinical evaluation of intralesional triamcinolone acetonide for ulcerative oral lichen planus.J Oral Pathol Med. 2006; 35:327-331.
Little J, Falace D, Miller. Dental management of medically compromised patient.7th Ed, Philadelphia: Mosby, 2007: p.236-245.
Carrozzo M, Thorpe R. Oral lichen planus: a review. Minerva Stomatol. 2009; 58:519-537.
Jajarm HH, Falaki F, Mahdavi O. A comparative pilot study of low intensity laser versus topical corticosteroids in the treatment of erosive-atrophic oral lichen planus. Photomed Laser Surg. 2011; 29:421-425.
Mirazii-Dizgah I, Ojaghi R, Roodsari HR. Attenuation of morphine withdrawal signs by low level laser therapy in rats.Behav Brain Res. 2009; 196(2):268-70.
Cavalcanti TM, Almeida-Barros RQ, CatÃ¢o MH. Knowledge of the physical properties and interaction of laser with biological tissue in dentistry. Ann Bras Dermatol. 2011; 86:955-960.
Trehan M, Taylor CR. Low-dose excimer 308-nm laser for the treatment of oral lichen planus. Arch Dermatol. 2004; 140:415-20.
KÃ¶llner K, Wimmershoff M, Landthaler M, Hohenleutner U. Treatment of oral lichen planus with the 308nm UVB excimer laser-early preliminary results in eight patients. Lasers Surg Med. 2003; 33:158-60.
Mahdavi O, Boostani N, Jajarm H, Falaki F. Use of low level laser therapy for oral lichen planus: report of two cases. J Dent (Shiraz). 2013; 14(4):201-4.
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