Newly Diagnosed Diabetes and Stress Glycaemia and Its’ Association with Acute Coronary Syndrome

Authors

  • Gordana Kamceva University "Goce Delchev", Faculty of Medical Sciences, Clinical Hospital Shtip, Shtip
  • Marija Vavlukis Ss Cyril and Methodius University of Skopje, Faculty of Medicine, University Clinic for Cardiology, Skopje
  • Darko Kitanoski Ss Cyril and Methodius University of Skopje, Faculty of Medicine, University Clinic for Cardiology, Skopje
  • Sashko Kedev Ss Cyril and Methodius University of Skopje, Faculty of Medicine, University Clinic for Cardiology, Skopje

DOI:

https://doi.org/10.3889/oamjms.2015.103

Keywords:

diabetes mellitus, stress glycaemya, hemoglobin A1C, acute coronary syndrome, cardiac events

Abstract

BACKGROUND: Diabetes is diagnosed in 10-20% of patients with acute coronary syndrome (ACS) not known to be diabetics. Elevated blood glucose is an independent risk factor for cardiac events, regardless of presence of diabetes.

AIM: Evaluating the prevalence of new-diagnosed DM among patients with ACS, and assessing the relationship between stress glycaemia and new diagnosed DM with in-hospital cardiac events.

METHODS: Prospective observational study, in patients with ACS, in whom we analyzed parameters of glycemic metabolism, clinical data, and in-hospital cardiac events. We comparatively analyzed patients according to the HgbA1C and known DM in five groups: non-DM (< 5.6%), new pre-DM (5.6-6.5%), new DM (≥ 6.5%), controlled (<7%) and uncontrolled (≥7%) known DM.

RESULTS: 150 patients, (93 male and 57 female) were included. Impaired glucose metabolism was detected in 44.5% of patients, 7.9% of whom were newly-diagnosed DM. The highest levels of stress glycaemia were found in new and uncontrolled known DM. The in-hospital event rate was 20.7%, the mortality rate 7.3%, being the highest in new diagnosed and uncontrolled known DM patients.

CONCLUSIONS: The prevalence of unknown DM was high among patients with ACS. Stress glycaemia and failure to achieve glycemic controlee, were an independent predictors of in-hospital cardiac events.

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References

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Published

2015-09-30

How to Cite

1.
Kamceva G, Vavlukis M, Kitanoski D, Kedev S. Newly Diagnosed Diabetes and Stress Glycaemia and Its’ Association with Acute Coronary Syndrome. Open Access Maced J Med Sci [Internet]. 2015 Sep. 30 [cited 2021 Dec. 4];3(4):607-12. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2015.103

Issue

Section

B - Clinical Sciences

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