Role and Importance of Chlamydia Trachomatis in Pregnant Patients

Authors

  • Mariya Angelova Angelova Department of Obstetrics and Gynecology, Trakia University, Faculty of Medicine, Stara Zagora
  • Emil Kovachev Department of Obstetrics and Gynecology, Paraskev Stoyanov Medical University, Varna
  • Veselina Tsankova Department of Obstetrics and Gynecology, Trakia University, Faculty of Medicine, Stara Zagora
  • Iliana Koleva Department of Obstetrics and Gynecology, Trakia University, Faculty of Medicine, Stara Zagora
  • Silvia Mangarova Department of Obstetrics and Gynecology, Trakia University, Faculty of Medicine, Stara Zagora

DOI:

https://doi.org/10.3889/oamjms.2016.077

Keywords:

Chlamydia trachomatis, pregnancy, neonatal infections, respiratory symptoms, polymerase chain reaction

Abstract

AIM: The aim of this study was to assess the prevalence of chlamydial infection among pregnant women and to determine the role of this infection in the fetus.

MATERIAL AND METHODS: In the first phase of this study were reported 58 pregnant women with a positive test for active chlamydial infection by applying immunofluorescence. In the second phase of the study were reported pregnant with premature burst membranes (PBM), postnatal complications associated with chlamydial infection as puerperal endometritis, and newborns are monitored for low birth weight and growth retardation at birth.

RESULTS: With a positive test are 58 patients in the first trimester or pregnancy registration in our consultation. After regimen with Sumamed (2 x 500 mg for three days and after 10 days again same scheme for them and their partner) at the beginning of the third trimester, the PCR test was made again. Of these, 5 were positive again, participants are between 20 and 30 years old. With premature rupture of OM are 20 patients. There was no increased incidence of premature births. Infants born to infected mothers have a higher risk of developing respiratory symptoms in the first 60 days of life. 3 of them have low for his age bodyweight.

CONCLUSIONS: The scarcity of data on manifestations of chlamydial infection during pregnancy and neonatal outcomes justifies this study. Early diagnosis for registration of pregnancy and timely treatment of chlamydial infection as well as scrutinising the infection during the third trimester of pregnancy can prevent infection of the newborn. Therefore, preventive examinations should be considered as a priority for early detection of asymptomatic chlamydial infection in the conduct of antenatal care.

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References

Alencar AAF, Ferreira LCL, Loureiro JAS. Detecção de Chlamydia trachomatis por imunofluorescência direta em esfregaços endocervicais. J Bras Ginecol. 1993;103:199–203.

Ward BJ, Plourde P. Travel and sexually transmitted infection. J Travel Med. 2006;13 :300–317. http://dx.doi.org/10.1111/j.1708-8305.2006.00061.x PMid:16987130

Santos C, Teixeira F, Vicente A, Astolfi-Filho S. Detection of Chlamydia trachomatis in endocervical smears of sexually active women in Manaus-AM, by PCR. Braz J Infect Dis. 2003;2:91–95.

Jalil EM, Pinto VM, Benzaken, et al AS. Prevalence of Chlamydia and Neisseria gonorrhoeae infections in pregnant women in six Brazilian cities. Rev Bras Ginecol Obstet. 2008;30:614–619. PMid:19219343

Fenton KA, Lowndes CM. Recent trends in the epidemiology of sexually transmitted infections in the European Union. Sex Transm Infect. 2004;80:255–263. http://dx.doi.org/10.1136/sti.2004.009415 PMid:15295121 PMCid:PMC1744866

Urdea M, Penny LA, Olmsted SS, Giovanni MY, Kaspar P, Shepherd A, Wilson P, Dahl CA, Buchsbaum S, Moeller G, Hay Burgess DC. Requirements for high impact diagnostics in the developing world. Nature. 2006;444(Suppl 1):73-9. http://dx.doi.org/10.1038/nature05448 PMid:17159896

Ilieva V, Nikolova G, Gadjeva V. Lipid Peroxidation and Catalase Activities in Patients with Chronic Obstructive Pulmonary Disease: A Comparative Study with Other Pulmonary Disease. Trakia Journal of Sciences. 2014;2:177-181.

Published

2016-08-05

How to Cite

1.
Angelova MA, Kovachev E, Tsankova V, Koleva I, Mangarova S. Role and Importance of Chlamydia Trachomatis in Pregnant Patients. Open Access Maced J Med Sci [Internet]. 2016 Aug. 5 [cited 2024 Apr. 19];4(3):410-2. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2016.077

Issue

Section

B - Clinical Sciences

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