Heart Failure Predictors in a Group of Patients with Myocardial Infarction

Authors

  • Sokol Myftiu Service of Cardiology, University Hospital Centre Tirana, Albania.
  • Petrit Bara Service of Cardiology, University Hospital Centre Tirana, Albania.
  • Ilir Sharka Service of Cardiology, University Hospital Centre Tirana, Albania
  • Artan Shkoza Biomedical and Experimental Department, Faculty of Medicine, University of Medicine, Tirana, Albania
  • Xhina Belshi Service of Cardiology, University Hospital Centre Tirana, Albania
  • Edlira Rruci Biomedical and Experimental Department, Faculty of Medicine, University of Medicine, Tirana, Albania
  • Gentian Vyshka Faculty of Medicine, University of Medicine in Tirana, Albania. http://orcid.org/0000-0001-5286-1265

DOI:

https://doi.org/10.3889/oamjms.2016.101

Keywords:

Heart Failure (HF), Acute Myocardial Infarction (AMI), ejection fraction (EF), epidemiology, prognosis

Abstract

AIM: The present study considers of the prevalence of heart failure (HF) in patients suffering from acute myocardial infarction (AMI) in the University Hospital Centre of Tirana (UHCT) “Mother Theresaâ€; the demographic and clinical characteristics of the sample during hospitalization; and the main predictors of heart failure occurrence inside the group of patients suffering an AMI.

MATERIAL AND METHODS: During a period of study from 2013-2015 we studied demographic and clinical data from 587 consecutive patients presenting with AMI; Framingham criteria were adopted for classifying patients with HF upon admission.

RESULTS: A Killip class ≥ 2 was the main diagnostic criterion of HF during hospitalisation. HF was identified in 156 patients (26.6%). The subgroup with HF had significant differences when compared with the other patients with regard to age, sex (male), heart rate upon admission, systolic blood pressure on admission, previous episodes of AMI, glycemia on admission, previous antihypertensive treatment, previous revascularization procedures, peripheral vascular disease, chronic renal disease, ejection fraction (EF), anemia, and atrial fibrillation presence. Independent predictors for HF occurrence in the logistic regression model were EF, previous revascularization, peripheral vascular disease, age, sex, previous AMI, systolic blood pressure upon admission, and anaemia.

CONCLUSION: As a conclusion, HF seems to be a common occurrence after AMI, in spite of changes in the epidemiological profile of the acute coronary syndrome. An increase in the incidence is registered as well, parallel to a decrease in the mortality following AMI. Attention must be shown for highly risked subpopulations, aged persons, patients with the previous coronary disease, and concomitant conditions.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Cowie MR, Lacey L, Tabberer M. Heart Failure After Myocardial Infarction: A Neglected Problem? Br J Cardiol. 2005;12(3):205-208.

Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013; 34: 3028-3034. http://dx.doi.org/10.1093/eurheartj/eht356 PMid:24014390

Nabel EG, Braunwald E. A tale of coronary artery disease and myocardial infarction. N Engl J Med. 2012; 366: 54-63. http://dx.doi.org/10.1056/NEJMra1112570 PMid:22216842

Sulo E, Vollset SE, Nygard O, Sulo G, Igland J, Egeland GM, Ebbing M, Tell GS. Trends in 28-day and 1-year mortality rates in patients hospitalized for a first acute myocardial infarction in Norway during 2001-2009: a "Cardiovascular disease in Norway" (CVDNOR) project. J Intern Med. 2015; 277: 353-361. http://dx.doi.org/10.1111/joim.12266 PMid:24815825

Koopman C, Bots ML, van Oeffelen AA, van Dis I, Verschuren WM, Engelfriet PM, Capewell S, Vaartjes I. Population trends and inequalities in incidence and short-term outcome of acute myocardial infarction between 1998 and 2007. Int J Cardiol. 2013; 168: 993-998. http://dx.doi.org/10.1016/j.ijcard.2012.10.036 PMid:23168007

Kostis WJ, Deng Y, Pantazopoulos JS, Moreyra AE, Kostis JB, Myocardial Infarction Data Acquisition System Study G. Trends in mortality of acute myocardial infarction after discharge from the hospital. Circ Cardiovasc Qual Outcomes. 2010; 3: 581-589. http://dx.doi.org/10.1161/CIRCOUTCOMES.110.957803 PMid:20923995

Bucholz EM, Butala NM, Rathore SS, Dreyer RP, Lansky AJ, Krumholz HM. Sex differences in long-term mortality after myocardial infarction: a systematic review. Circulation. 2014; 130: 757-767. http://dx.doi.org/10.1161/CIRCULATIONAHA.114.009480 PMid:25052403 PMCid:PMC4415526

Cleland JG, McGowan J. Heart failure due to ischaemic heart disease: epidemiology, pathophysiology and progression. J Cardiovasc Pharmacol. 1999;33(suppl 3):S17-S29. PMid:10442681

Fox KF, Cowie MR, Wood DA et al. Coronary artery disease as the cause of incident heart failure in the population. Eur Heart J. 2001;22:228-36. http://dx.doi.org/10.1053/euhj.2000.2289 PMid:11161934

British Heart Foundation. Coronary Heart Disease Statistics Database. London: British Heart Foundation, 2003. Available at www.bhf.org.uk

Spencer FA, Meyer TE, Gore JM, Goldberg RJ. Heterogeneity in the management and outcomes of patients with acute myocardial infarction complicated by heart failure: the National Registry of Myocardial Infarction. Circulation. 2002; 105: 2605–2610. http://dx.doi.org/10.1161/01.CIR.0000017861.00991.2F PMid:12045165

Vaur L, Danchin N, Genes N et al. Epidemiology of myocardial infarction in France: therapeutic and prognostic implications of heart failure during the acute phase. Am Heart J. 1999;137:49-58. http://dx.doi.org/10.1016/S0002-8703(99)70459-X

Hellermann JP, Jacobsen SJ, Gersh BJ et al. Heart failure after myocardial infarction: a review. Am J Med. 2002;113:324-30. http://dx.doi.org/10.1016/S0002-9343(02)01185-3

Hung J, Teng TH, Finn J, Knuiman M, Briffa T, Stewart S, Sanfilippo FM, Ridout S, Hobbs M. Trends from 1996 to 2007 in incidence and mortality outcomes of heart failure after acute myocardial infarction: a population-based study of 20,812 patients with first acute myocardial infarction in Western Australia. J Am Heart Assoc. 2013; 2: e000172. http://dx.doi.org/10.1161/JAHA.113.000172 PMCid:PMC3835218

Burazeri G, Goda A, Sulo G, Stefa J, Roshi E, Kark JD. Conventional risk factors and acute coronary syndrome during a period of socioeconomic transition: population-based case-control study in Tirana, Albania. Croat Med J. 2007; 48: 225-233. PMid:17436387 PMCid:PMC2080510

Hasdai D, Topol EJ, Kilaru R, Battler A, Harrington RA, Vahanian A, Ohman EM, Granger CB, Van de Werf F, Simoons ML, O'Connor CM, Holmes DR Jr. Frequency, patient characteristics, and outcomes of mild-to-moderate heart failure complicating ST-segment elevation acute myocardial infarction: lessons from 4 international fibrinolytic therapy trials. Am Heart J. 2003; 145: 73–79. http://dx.doi.org/10.1067/mhj.2003.53 PMid:12514657

Velazquez EJ, Francis GS, Armstrong PW, Aylward PE, Diaz R, O'Connor CM, White HD, Henis M, Rittenhouse LM, Kilaru R, van Gilst W, Ertl G, Maggioni AP, Spac J, Weaver WD, Rouleau JL, McMurray JJ, Pfeffer MA, Califf RM; VALIANT registry. An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry. Eur Heart J. 2004; 25: 1911–1919. http://dx.doi.org/10.1016/j.ehj.2004.08.006 PMid:15522470

Velagaleti RS, Pencina MJ, Murabito JM, Wang TJ, Parikh NI, D'Agostino RB, Levy D, Kannel WB, Vasan RS. Long-term trends in the incidence of heart failure after myocardial infarction. Circulation. 2008; 118: 2057–2062. http://dx.doi.org/10.1161/CIRCULATIONAHA.108.784215 PMid:18955667 PMCid:PMC2729712

Myftiu S, Sulo E, Burazeri G, Sharka I, Shkoza A, Sulo G. A higher burden of metabolic risk factors and underutilization of therapy among women compared to men might influence a poorer prognosis: a study among acute myocardial patients in Albania, a transitional country in Southeastern Europe. Croat Med J. 2015 Dec 31;56(6):542-9. http://dx.doi.org/10.3325/cmj.2015.56.542 PMid:26718760 PMCid:PMC4707925

Published

2016-09-06

How to Cite

1.
Myftiu S, Bara P, Sharka I, Shkoza A, Belshi X, Rruci E, Vyshka G. Heart Failure Predictors in a Group of Patients with Myocardial Infarction. Open Access Maced J Med Sci [Internet]. 2016 Sep. 6 [cited 2024 Apr. 25];4(3):435-8. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2016.101

Issue

Section

B - Clinical Sciences

Most read articles by the same author(s)