An Updated Mini Review of Vitamin D and Obesity: Adipogenesis and Inflammation State

Authors

  • Zujaja-Tul-Noor Hamid Mehmood Zayed University
  • Dimitrios Papandreou Zayed University

DOI:

https://doi.org/10.3889/oamjms.2016.103

Keywords:

1, 25(OH)2D3, obesity, adipocyte, inflammation

Abstract

Vitamin D related research continues to expand and theorise regarding its involvement in obesity, as both hypovitaminosis D and obesity strike in pandemic proportions. Vitamin D plays an important role in immune system through Vitamin D Receptors (VDR), which are transcription factors located abundantly in the body. Due to this characteristic, it is potentially linked to obesity, which is a state of inflammation involving the release of cytokines from adipose tissue, and exerting stress on other organs in a state of positive energy balance. Research trials in the past couple of years and systematic reviews from SCOPUS and MEDLINE will be discussed. The role of Vitamin D throughout the lifespan (from fetal imprinting until older age), and in various other obesity mediated chronic conditions shall be highlighted. Various mechanisms attributed to the inverse relationship of Vitamin D and obesity are discussed with research gaps identified, particularly the role of adipokines, epigenetics, calcium and type of adipose tissue.

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Published

2016-09-06

How to Cite

1.
Hamid Mehmood Z-T-N, Papandreou D. An Updated Mini Review of Vitamin D and Obesity: Adipogenesis and Inflammation State. Open Access Maced J Med Sci [Internet]. 2016 Sep. 6 [cited 2024 Mar. 28];4(3):526-32. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2016.103

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F - Review Articles

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