Antibiotic Utilization in Pediatric Hospitalized Patients â€“ A Single Center Study

Hasime Qorraj Bytyqi; Rexhep Hoxha; Elton Bahtiri; Valon Krasniqi; Shaip Krasniqi

doi:10.3889/oamjms.2017.045

Authors

Hasime Qorraj Bytyqi The University of Prishtina, Faculty of Medicine, Institute of Pharmacology, Prishtina, Kosovo http://orcid.org/0000-0001-9028-3806
Rexhep Hoxha The University of Prishtina, Faculty of Medicine, Institute of Pharmacology, Prishtina, Kosovo
Elton Bahtiri The University of Prishtina, Faculty of Medicine, Institute of Pharmacology, Prishtina, Kosovo
Valon Krasniqi The University of Prishtina, Faculty of Medicine, Institute of Pharmacology, Prishtina, Kosovo
Shaip Krasniqi The University of Prishtina, Faculty of Medicine, Institute of Pharmacology, Prishtina, Kosovo

DOI:

https://doi.org/10.3889/oamjms.2017.045

Keywords:

, children, antibiotics, utilisation, surveillance, hospital

Abstract

BACKGROUND: Antibiotics are among the most commonly prescribed drugs in paediatrics. In most cases, antibiotics are started on an empirical basis, without proof of a bacterial infection, either before the start of therapy or afterwards.

AIM: The main objective of this study was to analyse the consumption of antibiotics in hospitalised paediatric patients.

MATERIAL AND METHODS: This retrospective study investigated the consumption of antimicrobials in defined daily doses (DDDs according to the Anatomical Therapeutical Chemical/DDD index) in Pulmonology, Gastroenterology and Nephrology Departments at Pediatric Clinic of the tertiary hospital. The data on the consumption of antimicrobials were collected for five years by using properly designed form. The consumption was related to days of hospital care.

RESULTS: The most utilised antibiotics group in all three departments Pulmonology, Gastroenterology and Nephrology Departments were penicillins. Cephalosporins were mostly used in Pulmonology department. Metronidazole and Chloramphenicol were used in minimal quantities in all three departments.

CONCLUSION: This study demonstrates that surveillance programs on antibiotic resistance should be established and accompanied by analyses of drug utilisation data which can aid in the creation of valid cross-national studies on antibiotic usage and resistance, to motivate improvements in prescribing and guideline-directed antibiotic prescribing.

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