Pustular Palmoplantar Psoriasis Successfully Treated with Nb-UVB Monochromatic Excimer Light: A Case-Report


  • Serena Gianfaldoni University G. Marconi of Rome, Dermatology and Venereology, Rome 00192
  • Georgi Tchernev Medical Institute of the Ministry of Interior, Dermatology, Venereology and Dermatologic Surgery; Onkoderma, Private Clinic for Dermatologic Surgery, Dermatology and Surgery, Sofia 1606
  • Uwe Wollina Krankenhaus Dresden-Friedrichstadt, Department of Dermatology and Venereology, Dresden, Sachsen
  • Torello Lotti Universitario di Ruolo, Dipartimento di Scienze Dermatologiche, Università degli Studi di Firenze, Facoltà di Medicina e Chirurgia, Dermatology, Via Vittoria Colonna 11, Rome 00186




psoriasis, palmoplantar, monochromatic excimer light, UVB, treatment


Barber’s palmoplantar pustulosis (PPP) is a form of localised pustular psoriasis, affecting the palmar and plantar surfaces. It is a chronic disease, with a deep impact on the patients’ quality of life. The Authors discuss a case of Baber Psoriasis successfully treated with monochromatic excimer light.


Download data is not yet available.


Metrics Loading ...

Plum Analytics Artifact Widget Block


Meier M, Sheth PB. Clinical spectrum and severity of psoriasis. Curr Probl Dermatol. 2009;38:1-20. https://doi.org/10.1159/000232301 PMid:19710547

Mavilia L, Mori M, Rossi R, Campolmi P, Puglisi Guerra A, Lotti T. 308 nm monochromatic excimer light in dermatology: personal experience and review of the literature. G Ital Dermatol Venereol. 2008;143:329-337. PMid:18833074

Tauber M, Bal E, Pei XY, Madrange M, Khelil A, Sahel H, Zenati A, Makrelouf M, Boubridaa K, Chiali A, Smahi N, Otsmane F, Bouajar B, Marrakchi S, Turki H, Bourrat E, Viguier M, Hamel Y, Bachelez H, Smahi A. IL36RN mutations affect protein expression and function: A basis for genotype-phenotype correlation in pustular diseases. J Invest Dermatol. 2016;136:1811-1819. https://doi.org/10.1016/j.jid.2016.04.038 PMid:27220475

Naldi L. Epidemiology of psoriasis. Curr Drug Targets Inflamm Allergy. 2004;3(2):121-8. https://doi.org/10.2174/1568010043343958 PMid:15180464

Farley E, Masrour S, McKey J, Menter A. Palmoplantar psoriasis: a phenotypical and clinical review with introduction of a new quality-of-life assessment tool. J Am Acad Dermatol. 2009;60:1024-1031. https://doi.org/10.1016/j.jaad.2008.11.910 PMid:19467374

Yamamoto T. Extra-palmoplantar lesions associated with palmoplantar pustulosis. J Eur Acad Dermatol Venereol. 2009;23:1227-1232. https://doi.org/10.1111/j.1468-3083.2009.03296.x PMid:19453807

Brunasso AMG, Massone C. Can we really separate palmoplantar pustulosis from psoriasis? J Eur Acad Dermatol Venereol. 2010;24:619-621. https://doi.org/10.1111/j.1468-3083.2010.03648.x PMid:20337817

Stam MA, Bloem JL, De Schepper AM. Chronic recurrent multifocal osteomyelitis associated to psoriasis. JBR-BTR. 2007;90:212-213. PMid:17696102

Sallés M, Olivé A, Perez-Andres R, Holgado S, Mateo L, Riera E, Tena X. The SAPHO syndrome: a clinical and imaging study. Clin Rheumatol. 2011;30:245-249. https://doi.org/10.1007/s10067-010-1560-x PMid:20878342

Benjegerdes KE, Hyde K, Kivelevitch D, Mansouri B. Pustular psoriasis: pathophysiology and current treatment perspectives. Psoriasis: Targets Therapy 2016; 6:131-144. https://doi.org/10.2147/PTT.S98954

Marsland AM, Chalmers RJ, Hollis S, Leonardi-Bee J, Griffiths CE. Interventions for chronic palmoplantar pustulosis. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD001433. PMid:16437433

Laws PM, Young HS. Topical treatment of psoriasis. Expert Opin Pharmacother. 2010;11:1999-2009. https://doi.org/10.1517/14656566.2010.492778 PMid:20569091

Tempark T, Phatarakijnirund V, Chatproedprai S, Watcharasindhu S, Supornsilchai V, Wananukul S. Exogenous Cushing's syndrome due to topical corticosteroid application: case report and review literature. Endocrine. 2010;38:328-334. https://doi.org/10.1007/s12020-010-9393-6 PMid:20972726

Lee CS, Li K. A review of acitretin for the treatment of psoriasis. Expert Opin Drug Saf. 2009;8:769-79. https://doi.org/10.1517/14740330903393732

Stefanaki C, Kontochristopoulos G, Kedikoglou S, Hatziolou E, Zakopoulou N. Subcorneal pustular dermatosis associated with palmo-plantar pustular psoriasis: response to colchicine therapy. J Dermatol. 2004;31:946-948. https://doi.org/10.1111/j.1346-8138.2004.tb00634.x PMid:15729873

Adişen E, Tekin O, Gülekon A, Gürer MA. A retrospective analysis of treatment responses of palmoplantar psoriasis in 114 patients. J Eur Acad Dermatol Venereol. 2009;23:814-819. https://doi.org/10.1111/j.1468-3083.2009.03197.x PMid:19470063

Erkko P, Granlund H, Remitz A, Rosen K, Mobacken H, Lindelöf B, Reitamo S. Double- blind placebo-controlled study of long-term low-dose cyclosporin in the treatment of palmoplantar pustulosis. Br J Dermatol. 1998;139:997-1004. https://doi.org/10.1046/j.1365-2133.1998.02555.x PMid:9990362

Kumar B, Sandhu K, Kaur I. Topical 0.25% methotrexate gel in a hydrogel base for palmoplantar psoriasis. J Dermatol. 2004;31:798-801. https://doi.org/10.1111/j.1346-8138.2004.tb00602.x PMid:15672706

Redon E, Bursztejn AC, Loos C, Barbaud A, Schmutz JL. A retrospective efficacy and safety study of UVB-TL01 phototherapy and PUVA therapy in palmoplantar psoriasis. Ann Dermatol Venereol 2010;137:597-603. https://doi.org/10.1016/j.annder.2010.06.016 PMid:20932438

Han L, Somani AK, Huang Q, Fang X, Jin Y, Xiang LH, Zheng ZZ. Evaluation of 308-nm monochromatic excimer light in the treatment of psoriasis vulgaris and palmoplantar psoriasis. Photodermatol Photoimmunol Photomed. 2008;24:231-236. https://doi.org/10.1111/j.1600-0781.2008.00364.x PMid:18811863

Bianchi B, Campolmi P, Mavilia L, Danesi A, Rossi R, Cappugi P. Monochromatic excimer light (308 nm): an immunohistochemical study of cutaneous T cells and apoptosis-related molecules in psoriasis. J Eur Acad Dermatol Venereol. 2003;17:408-413. https://doi.org/10.1046/j.1468-3083.2003.00758.x PMid:12834450

Nisticò SP, Saraceno R, Stefanescu S, Chimenti S. A 308-nm monochromatic excimer light in the treatment of palmoplantar psoriasis. J Eur Acad Dermatol Venereol. 2006;20:523-526. https://doi.org/10.1111/j.1468-3083.2006.01503.x PMid:16684278

Wollina U, Koch A, Scheibe A, Seme B, Streit I, Schmidt WD. Targeted 307 nm UVB- phototherapy in psoriasis. A pilot study comparing a 307 nm excimer light with topical dithranol. Skin Res Technol. 2012;18:212-218. https://doi.org/10.1111/j.1600-0846.2011.00556.x PMid:22092772

Wollina U, Koch A, Scheibe A, Seme B, Streit I, Schmidt WD. Targeted 307 nm UVB- excimer light vs. topical dithranol in psoriasis. J Eur Acad Dermatol Venereol. 2012;26:122-3. https://doi.org/10.1111/j.1468-3083.2010.03972.x PMid:21251088



How to Cite

Gianfaldoni S, Tchernev G, Wollina U, Lotti T. Pustular Palmoplantar Psoriasis Successfully Treated with Nb-UVB Monochromatic Excimer Light: A Case-Report. Open Access Maced J Med Sci [Internet]. 2017 Jul. 19 [cited 2023 Feb. 4];5(4):462-6. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2017.080

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>