Interdigital Melanoma of the Foot Affecting Two Neighbouring Interdigital Spaces â€“ Second Case Report

Uwe Wollina; Carsten Rilke; Gesina Hansel; Dana Langer; Jacqueline SchÃ¶nlebe; Georgi Tchernev

doi:10.3889/oamjms.2017.112

Authors

Uwe Wollina Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt in Dresden, Dresden
Carsten Rilke Department for Vascular Surgery, Endovascular Surgery, Phlebology, Dresden, Sachsen
Gesina Hansel Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt in Dresden, Dresden
Dana Langer Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt in Dresden, Dresden
Jacqueline SchÃ¶nlebe Institute of Pathology â€œGeorg Schmorlâ€, Academic Teaching Hospital Dresden-Friedrichstadt, Friedrichstrasse 41, 01067 Dresden
Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, and Onkoderma Policlinic for Dermatology and Dermatologic Surgery, Sofia

DOI:

https://doi.org/10.3889/oamjms.2017.112

Keywords:

Melanoma, acrolentiginous melanoma, Mohs surgery, interdigital spaces, staging

Abstract

Melanoma affecting two interdigital spaces has been recently described by our group for the first time in medical literature. Here we present a second patient with acrolentiginous melanoma of the sole affecting the 1st and 2nd interdigital space. The tumour was removed by delayed Mohs surgery. Due to the extension of the melanoma, digit II and III had to be removed. Staging excluded metastatic spread. The tumour was classified as pT4bN0M0.

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References

Haenssle HA, Hoffmann S, Buhl T, Emmert S, SchÃ¶n MP, Bertsch HP, Rosenberger A. Assessment of melanoma histotypes and associated patient-related factors: basis for a predictive statistical model. J Dtsch Dermatol Ges. 2015;13(1):37-45. https://doi.org/10.1111/ddg.12561

Guarneri C, Bevelacqua V, Semkova K, Tchernev G, Tempel S, Wollina U. Subungual acrolentiginous amelanotic melanoma treated with amputation of the distal and middle phalanges. Wien Med Wochenschr. 2013;163(15-16):368-371. https://doi.org/10.1007/s10354-013-0194-4 PMid:23591855

Schoenewolf NL, Belloni B, Simcock M, Tonolla S, Vogt P, Scherrer E, Holzmann D, Dummer R. Clinical implications of distinct metastasizing preferences of different melanoma subtypes. Eur J Dermatol. 2014;24(2):236-241. PMid:24721680

Wollina U, Tchernev G, Chokoeva AA, Lotti T. Melanoma of the heel - a case series of a rare melanoma subtype. J Biol Regul Homeost Agents. 2015;29(1 Suppl):69-73. PMid:26016971

Sondermann W, Zimmer L, Schadendorf D, Roesch A, Klode J, Dissemond J. Initial misdiagnosis of melanoma located on the foot is associated with poorer prognosis. Medicine (Baltimore). 2016;95(29):e4332. https://doi.org/10.1097/MD.0000000000004332 PMid:27442685 PMCid:PMC5265802

Tchernev G, Lozev I, Pidakev I, Mangarov H, Grigorov Y, Cardoso JC, Popchristova E, Patterson JW, Lotti T, Pehlivanov G, Voicu C, Clatici VG, Wollina U. Interdigital melanoma affecting two neighboring interdigital spaces. First description in the medical literature. Wiener Med Wochenschr, 2017(in press). https://doi.org/10.1007/s10354-017-0558-2

Schoffer O, SchÃ¼lein S, Arand G, Arnholdt H, Baaske D, Bargou RC, Becker N, Beckmann MW, Bodack Y, BÃ¶hme B, Bozkurt T, Breitsprecher R, Buchali A, Burger E, Burger U, Dommisch K, Elsner G, Fernschild K, Flintzer U, Funke U, Gerken M, GÃ¶bel H, Grobe N, Gumpp V, Heinzerling L, Kempfer LR, Kiani A, Klinkhammer-Schalke M, KlÃ¶cking S, Kreibich U, Knabner K, Kuhn P, Lutze S, MÃ¤der U, Maisel T, Maschke J, Middeke M, Neubauer A, Niedostatek A, Opazo-Saez A, Peters C, Schell B, Schenkirsch G, Schmalenberg H, Schmidt P, Schneider C, Schubotz B, Seide A, Strecker P, Taubenheim S, Wackes M, WeiÃŸ S, Welke C, Werner C, Wittekind C, Wulff J, Zettl H, Klug SJ. Tumour stage distribution and survival of malignant melanoma in Germany 2002-2011. BMC Cancer. 2016;16(1):936. https://doi.org/10.1186/s12885-016-2963-0 PMid:27919243 PMCid:PMC5139127

Hiripi E, Gondos A, Emrich K, Holleczek B, Katalinic A, Luttmann S, Sirri E, Brenner H; GEKID Cancer Survival Working Group. Survival from common and rare cancers in Germany in the early 21st century. Ann Oncol. 2012;23(2):472-479. https://doi.org/10.1093/annonc/mdr131 PMid:21597096

Goydos JS, Shoen SL. Acral lentiginous melanoma. Cancer Treat Res. 2016;167:321-329. https://doi.org/10.1007/978-3-319-22539-5_14 PMid:26601870

Carrera C, Gual A, DÃaz A, Puig-ButillÃ© JA, NoguÃ¨s S, Vilalta A, Conill C, Rull R, Vilana R, Arguis P, Vidal-Sicart S, AlÃ³s L, Palou J, Castel T, Malvehy J, Puig S. Prognostic role of the histological subtype of melanoma on the hands and feet in Caucasians. Melanoma Res. 2017. https://doi.org/10.1097/CMR.0000000000000340 PMid:28296711

Wada M, Ito T, Tsuji G, Nakahara T, Hagihara A, Furue M, Uchi H. Acral lentiginous melanoma versus other melanoma: A single-center analysis in Japan. J Dermatol. 2017. https://doi.org/10.1111/1346-8138.13834

Liang WS, Hendricks W, Kiefer J, Schmidt J, Sekar S, Carpten J, Craig DW, Adkins J, Cuyugan L, Manojlovic Z, Halperin RF, Helland A, Nasser S, Legendre C, Hurley LH, Sivaprakasam K, Johnson DB, Crandall H, Busam KJ, Zismann V, Deluca V, Lee J, Sekulic A, Ariyan CE, Sosman J, Trent J. Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma. Genome Res. 2017;27(4):524-532. https://doi.org/10.1101/gr.213348.116 PMid:28373299

Lee KT, Kim EJ, Lee DY, Kim JH, Jang KT, Mun GH. Surgical excision margin for primary acral melanoma. J Surg Oncol. 2016;114(8):933-939. https://doi.org/10.1002/jso.24442 PMid:27642170