Erythema Ab Igne Successfully Treated With Mesoglycan and Bioflavonoids: A Case-Report

Serena Gianfaldoni; Roberto Gianfaldoni; Georgi Tchernev; Jacopo Lotti; Uwe Wollina; Torello Lotti

doi:10.3889/oamjms.2017.123

Authors

Serena Gianfaldoni University G. Marconi of Rome, Dermatology and Venereology, Rome 00192
Roberto Gianfaldoni University G. Marconi of Rome, Dermatology and Venereology, Rome 00192
Georgi Tchernev Medical Institute of the Ministry of Interior, Dermatology, Venereology and Dermatologic Surgery; Onkoderma, Private Clinic for Dermatologic Surgery, Dermatology and Surgery, Sofia 1407
Jacopo Lotti G. Marconi University, Department of Nuclear Physics, Subnuclear and Radiation, Rome
Uwe Wollina Krankenhaus Dresden-Friedrichstadt, Department of Dermatology and Venereology, Dresden, Sachsen
Torello Lotti Universitario di Ruolo, Dipartimento di Scienze Dermatologiche, UniversitÃ degli Studi di Firenze, FacoltÃ di Medicina e Chirurgia, Dermatology, Via Vittoria Colonna 11, Rome 00186

DOI:

https://doi.org/10.3889/oamjms.2017.123

Keywords:

erythema ab igne, heat exposure, malignant transformation, mesoglycan, bioflavonoids

Abstract

Erythema ab igne is a localised, cutaneous condition consisting of reticulate hyperpigmentation, epidermal atrophy, and telangiectasias. It is caused by repetitive and prolonged exposure to moderate heat that is insufficient for producing burns. Currently, erythema ab igne is most commonly observed following repeated use of hot water bottles, infrared lamps and heating pads. If not properly treated, erythema ab igne can become chronic and even malignant. We report a case of erythema ab igne, successfully treated with systemic mesoglycan-based therapy, and local therapy with bioflavonoids.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Kligman LH. Intensification of ultraviolet-induced dermal damage by infrared radiation. Arch Dermatol Res. 1982;272(3-4):229-38. https://doi.org/10.1007/BF00509050 PMid:7165330

Kokturk A, Kaya TI, Baz K, Yazici AC, Apa DD, Ikizoglu G. Bullous erythema ab igne. Dermatol Online J. 2003;9(3):18. PMid:12952765

Hirohata A, Hanafusa T, Igawa K, Inoue-Nishimoto T, Mabuchi-Kiyohara E, Nakai C, Kasugai T, Yokozeki H, Ikegami R. Bullous erythema ab igne with cutaneous reactive angiomatosis.Eur J Dermatol. 2016;26(2):191-2. PMid:27226050

Cavallari V, Cicciarello R, Torre V, Gagliardi ME, Albiero F, Palazzo R, Siragusa M, Schipis C. Chronic heat-induced skin lesions (erythema ab Igne): ultrastructural studies. Ultrastruct Pathol. 2001;25(2):93-7. https://doi.org/10.1080/01913120117614 PMid:11407533

LoPiccolo M, Crestanello J, Yoo SS, Sciubba J, FernÃ¡ndez C, Tausk FA. Facial erythema ab igne of rapid onset. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105(5):e38-40. https://doi.org/10.1016/j.tripleo.2008.01.008 PMid:18442733

Rudolph CM, Soyer HP, Wolf P, Kerl H. Squamous epithelial carcinoma in erythema ab igne. Hautarzt. 2000 Apr;51(4):260-3. https://doi.org/10.1007/s001050051031 PMid:10810662

Wollina U, Helm C, Hansel G, KÃ¶stler E, SchÃ¶nlebe J. Two cases of erythema ab igne, one with a squamous cell carcinoma. Giornale Italiano di Dermatologia e Venereologia. 2007;142(4):415-8.

Sahl W, Taira JW. Erythema ab igne: treatment with 5-fluorouracil cream. J Am Acad Dermatol. 1992; 27: 109-10. https://doi.org/10.1016/S0190-9622(08)80818-3

Kochs C, Hanneken S, Schulte KW, Reifenberger J. Treatment of carcinoma in situ of erythema ab igne with photodynamic therapy. Hautarzt. 2008;59(10):777-9. https://doi.org/10.1007/s00105-008-1634-8 PMid:18773179

Elsner P, Schliemann S. Erythema ab igne as an occupational skin disease. J Dtsch Dermatol Ges. 2014;12(7):621-2. PMid:24684647

Fischer J, Rein K, Erfurt-Berge C, de Zwaan M. Three cases of erythma ab igne (EAI) in patients with eating disorders. Neuropsychiatr. 2010;24(2):141-3. PMid:20605010

Mucklow ES, Freeman NV. Pancreatic ascites in childhood. Br J Clin Pract. 1990;44(6):248-51. PMid:2144996

Butler ML. Erythema ab igne, a sign of pancreatic disease. Am J Gastroenterol. 1977;67(1):77-9. PMid:851110

Dellavalle RP, Gillum P. Erythema ab igne following heating/cooling blanket use in the intensive care unit. Cutis. 2000;66(2):136-8. PMid:10955195

Arnold AW, Itin PH. Laptop computer-induced erythema ab igne in a child and review of the literature. Pediatrics. 2010;126(5):e1227-30. https://doi.org/10.1542/peds.2010-1390 PMid:20921068

Levinbook WS, Mallett J, Grant-Kels JM. Laptop computer--associated erythema ab igne. Cutis. 2007;80(4):319-20. PMid:18038695

Manoharan D. Erythema ab igne: Usual site, unusual cause. J Pharm Bioallied Sci. 2015; 7(Suppl 1): S74â€“S75. https://doi.org/10.4103/0975-7406.155811 PMid:26015756 PMCid:PMC4439716