Pigmented Paraaxillary Located "Complex" Basal Cell Carcinoma Imitating clinically irritated Melanocytic Lesion - Succesfull Surgical Approach in Bulgarian Patient

Cristiana Voicu; Mara Mihai; Mihai Lupu; James W. Patterson; Nely Koleva; Uwe Wollina; Torello Lotti; Jacopo Lotti; Katlein FranÃ§a; Atanas Batashki; Serena Gianfaldoni; Ilko Bakardzhiev; Hristo Mangarov; Georgi Tchernev

doi:10.3889/oamjms.2017.141

Authors

Cristiana Voicu Dermatology Department, Polisano Clinic, 26Z Timisoara Blvd, Bucharest
Mara Mihai Oncologic Dermatology and Allergology Department, â€Carol Davilaâ€, University of Medicine and Pharmacy, 17 Marasti Blvd, Bucharest
Mihai Lupu Dermatology Department, Medas Medical Centre, 41 Nicolae Grigorescu Blvd, Bucharest
James W. Patterson Department of Pathology, University of Virginia Health System, 1215 Lee Street, Box 800214, Charlottesville, VA 22908
Nely Koleva Department of Pathology, Medical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia
Uwe Wollina Department of Dermatology and Allergology, Academic Friedrichstrasse 41, 01067, Dresden
Torello Lotti Department of Dermatology, University of Rome â€œG. Marconiâ€, Rome
Jacopo Lotti Department of Nuclear, Subnuclear and Radiation Physics, University of Rome "G. Marconi", Rome
Katlein FranÃ§a Institute for Bioethics & Health Policy; Department of Dermatology & Cutaneous Surgery; Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine - Miami, FL
Atanas Batashki Abdominal and Thoracic Surgery, Department of Special Surgery, Medical University of Plovdiv, bul. "Peshtersko shose" Nr 66, 4000 Plovdiv
Serena Gianfaldoni University G. Marconi of Rome, Rome
Ilko Bakardzhiev Medical College, Medical University of Varna, Varna
Hristo Mangarov Medical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia
Georgi Tchernev Medical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia, Bulgaria; Onkodermaâ€ - Policlinic for Dermatology, Venereology and Dermatologic Surgery, 26 General Skobelev blvd., Sofia

DOI:

https://doi.org/10.3889/oamjms.2017.141

Keywords:

basal cell carcinoma, axillary region, basosquamous carcinoma

Abstract

BACKGROUND: Basal cell carcinoma (BCC) is the most frequently encountered neoplasm worldwide. While nodular BCC is the most frequent clinical subtype, other forms of BCC, such as superficial, cystic, morpheiform, infiltrative, and pigmented may also be encountered.

CASE PRESENTATION: We present the case of a 67-year-old male with a relatively well-defined infiltrative, pigmented plaque with multiple colours and peripheral growth situated in the right axillary region. The histopathologic examination performed after complete surgical excision of the tumour revealed a complex pigmented BCC with macronodular, fibroepithelioma-like, cystic, focally infiltrative and basosquamous features.

CONCLUSION: Uncommon locations of BCCs in sun-protected areas such as the axillary region require a higher degree of suspicion for diagnosis. The complex histology of the presented case, including subtypes with differing biologic attributes, emphasises the importance of histopathological examination in the diagnosis and therapeutic management of BCC.

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