The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury

Zvezdana Petronijevic; Gjulsen Selim; Lidija Petkovska; Ljubica Georgievska-Ismail; Goce Spasovski; Liljana Tozija

doi:10.3889/oamjms.2017.148

Authors

Zvezdana Petronijevic Uneversity Clinic of Nephrology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje
Gjulsen Selim University Clinic of Nephrology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje
Lidija Petkovska University Clinic of Toxicology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje
Ljubica Georgievska-Ismail University Clinic of Cardiology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje
Goce Spasovski University Clinic of Nephrology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje
Liljana Tozija University Clinic of Nephrology, Medical Faculty, Ss Cyril and Methodius University of Skopje, Skopje

DOI:

https://doi.org/10.3889/oamjms.2017.148

Keywords:

Acute kidney injury, elderly, treatment, outcome, hemodialysis

Abstract

BACKGROUND: Elderly population (â‰¥ 65) are more prone to develop acute kidney injury (AKI) compared to younger, also elderly with AKI have an increased requirement for dialysis treatment and an elevated risk of short-term and long-term mortality.

AIM: The objectives of this study were to examine the effect of treatment of short-term outcomes and mortality in elderly patients with AKI.

MATERIAL AND METHODS: Seventy elderly AKI patients, that filled one of the criteria of AKI definition and had hospitalization over 24 hours, were enrolled in the study.

RESULTS: The median age of patients was 74.28 Â± 6.64, with mean CCI (Charlson Comorbidity Index) score of 6.94 Â± 1.94. The majority of patients (70%) were classified at stage 3 of AKIN, 20% of patients were classified at stage 2 and 10% at stage 1. In the groups of patients with death outcome, the chronic cardiomyopathy was more frequently present (p = 0.034). Regarding treatment, 58.6% of the AKI patients underwent hemodialysis while 41.4% received conservative treatment. Mortality rate was 52.8%, out of which 28.6% was in-hospital mortality, while in 24.3% of patients death occurred in the follow-up period of 90 days.

CONCLUSION: In our study, short- term survival is not related to different treatment options. Applied treatment in elderly patients with AKI should be assessed by measuring the long term outcome.

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