Assessment of the Correlation between Severity of Coronary Artery Disease and Waist–Hip Ratio

Authors

  • Premtim Rashiti Cardiology Clinic, University Clinical Center of Kosovo, Prishtina, Kosovo
  • Ibrahim Behluli Department of Anatomy, University Clinical Center of Kosovo, Prishtina, Kosovo
  • Albiona Rashiti Bytyqi Department of Epidemiology, National Institute of Public Health in Kosovo, Prishtina, Kosovo

DOI:

https://doi.org/10.3889/oamjms.2017.211

Keywords:

waist/hip ratio, coronary artery disease, Gensini

Abstract

AIM: To study the correlation between waist/hip ratio as measure of obesity and severity of coronary artery disease (CAD) assessed by coronary angiography in Kosovo.

METHODS: The study includes 82 patients with suspected or known CAD referred for coronary angiography. All patients were subjected to full history taking, clinical examination including measurement of arterial blood pressure, body weight, height, BMI, waist circumference, hip circumferences, waist/hip ratio and waist/height ratio. Coronary angiography was performed by standard techniques to determine the presence and severity of coronary artery lesion by Gensini score.

RESULTS: Among the 82 patients included in the study, in CAD – group (mean age was 66.76 ± 9.12 years) and non-CAD group (mean age was 64.80 ± 8.30 years), patients in CAD group had BMI (mean 28.17 ± 3.32 kg/m2) and in non-CAD group had BMI (mean 28.76 ± 4.68 kg/m2 ). Patients in CAD group had waist/height ratio (mean 1.76 ± 7.56) and in non-CAD group had waist/height ratio (mean 0.57 ± 0.08). Patient in CAD group had waist/hip ratio (mean 0.93 ± 0.06) and in non-CAD group (mean 0.88 ± 0.07). Thirty seven patients (45.1%) had no coronary artery disease (Gensini score = 0), 15 patients (18.3%) had mild disease (Gensini score = 1-32), 14 patients (17.1%) had moderate disease (Gensini score = 32-58), 16 patients (19.5%) had severe disease (Gensini score ≥ 58).

CONCLUSION: There is a significant positive correlation between waist/hip ratio and presence and severity of coronary artery disease among Kosovar patients.

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References

Siavash M, Sadeghi M, Salarifar F, et al. Comparison of body mass index and waist/height ratio in predicting definite coronary artery disease. Ann Nutr Metab. 2009; 53 (3-4):162-6. https://doi.org/10.1159/000172977 PMid:19011279

Zhang Y, Hong J, Gu W, et al. Impact of the metabolic syndrome and its individual components on risk and severity of coronary heart disease. Endocrine. 2009; 36(2): 233-8. https://doi.org/10.1007/s12020-009-9214-y PMid:19618299

Malik M, Razig SA. The prevalence of the metabolic syndrome among the multiethnic population of the United Arab Emirates: A report of a national survey. Metab Syndr Relat Disord. 2008; 6(3):177-86. https://doi.org/10.1089/met.2008.0006 PMid:18699721

Prevalence of the metabolic syndrome in populations of Asian origin. Comparison of the IDF definition with the NCEP definition.Diabetes Res Clin Pract. 2007; 76(1):57-67. https://doi.org/10.1016/j.diabres.2006.07.020 PMid:17010470

Qiao Q, Pitkäniemi J, Tuomilehto J, et al. Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women. Diabetologia. 2006; 49(12):2837-46. https://doi.org/10.1007/s00125-006-0438-6 PMid:17021922

Wildman RP, Gu D, Reynolds K, et al. Are waist circumference and body mass index independently associated with cardiovascular disease risk in Chinese adults? Am J Clin Nutr. 2005; 82(6): 1195-202. PMid:16332651

Alberti KGMM, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: A joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International atherosclerosis society and international association for the study of obesity. Circulation. 2009; 120(16):1640-5. https://doi.org/10.1161/CIRCULATIONAHA.109.192644 PMid:19805654

Cameron AJ, Dunstan DW, Owen N, et al. Health and mortality consequences of abdominal obesity: Evidence from the AusDiab study. Med J Aust. 2009; 191(4):202-8. PMid:19705980

Pischon T, Boeing H, Hoffmann K, et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med. 2008; 359(20): 2105-20. https://doi.org/10.1056/NEJMoa0801891 PMid:19005195

Larsson B, Svärdsudd K, Welin L, Wilhelmsen L, Björntorp P, et al. Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. Br Med J (Clin Res Ed). 1984; 288: 1401–1404. https://doi.org/10.1136/bmj.288.6428.1401

Rimm EB, Willett WC, Hu FB, Sampson L, Colditz GA, et al. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA. 1998; 279: 359–364. https://doi.org/10.1001/jama.279.5.359 PMid:9459468

Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. American Journal of Cardiology. 1983; 51:606. https://doi.org/10.1016/S0002-9149(83)80105-2

World Health Organization. Waist Circumference and Waist-Hip Ratio Report of a WHO Expert Consultation. Geneva, 8-11 December 2008. WHO Press, World Health Organization; Geneva, Switzerland:2011

Després JP. CVD risk assessment: Do we need the metabolic syndrome or better global cardiometabolic risk calculators? International Journal of Obesity 32 2008; 32 (Suppl. 2): S1-4.

Welborn TA, Dhaliwal SS. Preferred clinical measures of central obesity for predicting mortality. European Journal of Clinical Nutrition. 2007; 61:1373-1379. https://doi.org/10.1038/sj.ejcn.1602656 PMid:17299478

Srikanthan P, Seeman TE, Karlamangla AS. Waist-hip-ratio as a predictor of all-cause mortality in high functioning older adults. Annals of Epidemiology, 2009; 19:724-731. https://doi.org/10.1016/j.annepidem.2009.05.003 PMid:19596204 PMCid:PMC3154008

Folsom AR, Kushi LH, Anderson KE, et al. Associations of general and abdominal obesity with multiple health outcomes in older women: The Iowa Women's Health Study. Arch Intern Med 2000; 160 (14): 2117-28. https://doi.org/10.1001/archinte.160.14.2117 PMid:10904454

Wildman RP, Gu D, Reynolds K, et al. Are waist circumference and body mass index independently associated with cardiovascular disease risk in Chinese adults? Am J Clin Nutr 2005; 82(6): 1195-202. PMid:16332651

Alberti KGMM, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: A joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International atherosclerosis society and international association for the study of obesity. Circulation 2009; 120(16):1640-5. https://doi.org/10.1161/CIRCULATIONAHA.109.192644 PMid:19805654

Cameron AJ, Dunstan DW, Owen N, et al. Health and mortality consequences of abdominal obesity: Evidence from the AusDiab study. Med J Aust 2009; 191(4):202-8. PMid:19705980

Després JP. CVD risk assessment: Do we need the metabolic syndrome or better global cardiometabolic risk calculators? Int J Obes. 2008; 32(Suppl. 2):S1-4. https://doi.org/10.1038/ijo.2008.27 PMid:18469833

Lakka HM, Lakka TA, Tuomilehto J, et al. Abdominal obesity is associated with increased risk of acute coronary events in men. Eur Heart J. 2002; 23(9):706-13. https://doi.org/10.1053/euhj.2001.2889 PMid:11977996

Molarius A, Seidell JC. Selection of anthropometric indicators for classification of abdominal fatness—a critical review. Int J Obes Relat Metab Disord. 1998; 22: 719–27. https://doi.org/10.1038/sj.ijo.0800660 PMid:9725630

Canoy D, Boekholdt SM, Wareham N, Luben R, Welch A, et al. Body fat distribution and risk of coronary heart disease in men and women in the European Prospective Investigation Into Cancer and Nutrition in Norfolk cohort: a population-based prospective study. Circulation. 2007; 116: 2933–2943. https://doi.org/10.1161/CIRCULATIONAHA.106.673756 PMid:18071080

Flint AJ, Rexrode KM, Hu FB, Glynn RJ, Caspard H, et al. Body mass index, waist circumference, and risk of coronary heart disease: a prospective study among men and women. Obesity research & clinical practice. 2010; 4: e171–e181. https://doi.org/10.1016/j.orcp.2010.01.001 PMCid:PMC2992336

Gray RS, Fabsitz RR, Cowan LD, Lee ET, Welty TK, et al. Relation of generalized and central obesity to cardiovascular risk factors and prevalent coronary heart disease in a sample of American Indians: the Strong Heart Study. Int J Obes Relat Metab Disord. 2000;24:849–860. https://doi.org/10.1038/sj.ijo.0801243 PMid:10918531

Page JH, Rexrode KM, Hu F, Albert CM, Chae CU, et al. Waist-height ratio as a predictor of coronary heart disease among women. Epidemiology. 2009; 20: 361–366. https://doi.org/10.1097/EDE.0b013e31819f38f1 PMid:19289960 PMCid:PMC4012298

Rexrode KM, Buring JE, Manson JE. Abdominal and total adiposity and risk of coronary heart disease in men. Int J Obes Relat Metab Disord. 2001; 25: 1047–1056. https://doi.org/10.1038/sj.ijo.0801615 PMid:11443505

Taylor AE, Ebrahim S, Ben-Shlomo Y, Martin RM, Whincup PH, et al. Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts. The American journal of clinical nutrition. 2010; 91: 547–556. https://doi.org/10.3945/ajcn.2009.28757 PMid:20089729

Rimm EB, Stampfer MJ, Giovannucci E, Ascherio A, Spiegelman D, Colditz GA, Willett WC. Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men. Am J Epidemiol. 1995; 141(12):1117-27. https://doi.org/10.1093/oxfordjournals.aje.a117385 PMid:7771450

Flint AJ, Rexrode KM, Hu FB, Glynn RJ, Caspard H, Manson JE, Willett WC, Rimm EB Body mass index, waist circumference, and risk of coronary heart disease: a prospective study among men Obes Res Clin Pract. 2010; 4(3):e171-e181. https://doi.org/10.1016/j.orcp.2010.01.001 PMCid:PMC2992336

Larsson B, Svardsudd K, Welin L, et al. Abdominal adipose tissue distribution, obesity and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. BMJ. 1984; 288: 1401-1404. https://doi.org/10.1136/bmj.288.6428.1401 PMid:6426576 PMCid:PMC1441047

Lapidus L, Bengtsson C, Larsson B, et al. Distribution of adipose tissue and risk of cardiovascular disease and death: A 12 year follow up of participants in the population study of women in Gothenburg, Sweden. BMJ. 1984; 289: 1257-1261. https://doi.org/10.1136/bmj.289.6454.1257 PMid:6437507 PMCid:PMC1443498

Published

2017-11-30

How to Cite

1.
Rashiti P, Behluli I, Bytyqi AR. Assessment of the Correlation between Severity of Coronary Artery Disease and Waist–Hip Ratio. Open Access Maced J Med Sci [Internet]. 2017 Nov. 30 [cited 2024 Apr. 24];5(7):929-33. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2017.211

Issue

Section

B - Clinical Sciences