Cerebral Venous Thrombosis in a Patient with Iron Deficiency Anemia and Thrombocytopenia: A Case Report
DOI:
https://doi.org/10.3889/oamjms.2017.216Keywords:
Cvt, Anemia, Thrombocytopenia, Case, ReportAbstract
AIM: To report a potential association of thrombosis, thrombocytopenia with iron deficiency anaemia.
CASE REPORT: A 43-year-old female experienced an episode of a headache, with bilateral papilledema by neurological examination, magnetic resonance venography (MRV) brain showed cerebrovenous thrombosis (CVT), iron deficiency anaemia and thrombocytopenia by blood investigations, that was treated with iron supplementations and anticoagulation.
CONCLUSION: In this patient, cerebrovenous thrombosis (CVT) was discovered in a patient with thrombocytopenia and iron deficiency anaemia and treated with iron supplements and anticoagulation, we concluded that thrombocytopenia is not a protective factor against thrombosis especially with iron deficiency anaemia.Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Iurlaro S, Beghi E, Massetto N, Guccione A, Autunno M, Colombo B, Di Monda T, Gionco M, Cortelli P, Perini F, D'Onofrio F, Agostoni E. Does a headache represent a clinical marker in early diagnosis of cerebral venous thrombosis? A prospective multicentric study. Neurol Sci. 2004;25:S298-S2. https://doi.org/10.1007/s10072-004-0317-1 PMid:15549568
ai-Hao Huang,Je-Jen Su,Po-Hsien Lin.Iro deficiency anemia-A rare etiology of sinus thrombosis I adults. Acta Neurologica Taiwanica. 2010;19:2.
Sébire G, Tabarki B, Saunders DE, Leroy I, Liesner R, Saint-Martin C, Husson B, Williams AN, Wade A, Kirkham FJ. Cerebral venous sinus thrombosis in children: risk factors, presentation, diagnosis and outcome. Brain. 2005;128,477-489. https://doi.org/10.1093/brain/awh412 PMid:15699061
Aoki N, Sakai T. Cerebral sinus thrombosis in patients with severe iron deficiency anaemia due to myoma uteri. Acta Neurochir (Wien). 1989; 97: 131–134. https://doi.org/10.1007/BF01772824
Ho BL,Huang P,Khor GT,Lin RT.Stimultaneous thrombosis of cerebral artery and venous sinus. Acta NeurolTaiwan. 2008;17:112-116. PMid:18686652
Kinoshita Y, Taniura S, Shishido H, Nojima T, Kamitani H, Watanebe T . Cerebral venous sinus thrombosis associated with iron deficiency: two case reports. Neurol Med Chir (Tokyo). 2006; 46:589–593. https://doi.org/10.2176/nmc.46.589
Balci K,Utku U, Asil T, Buyukkoyuncu N. Deep cerebral vein thrombosis associated with iron deï¬ciency anaemia in adults, Journal of Clinical Neuroscience. 2006; 14(2):181–184. https://doi.org/10.1016/j.jocn.2005.09.020 PMid:17161294
Ogata T, Kamouchi M, Kitazono T et al., Cerebral venous thrombosis associated with iron deï¬ciency anemia. Journal of Stroke and Cerebrovascular Diseases. 2008; 17(6):426– 428. https://doi.org/10.1016/j.jstrokecerebrovasdis.2008.04.008 PMid:18984440
Beguin Y. Erythropoietin and platelet production. Haematologica.1999; 84(6):541–547. PMid:10366799
Gupta M, Joseph G. Severe thrombocytopenia associated with iron deficiency. Hospital Physician. 2001; 37: 49-54.
Hartï¬eld DS, Lowry NJ, Keene DJ, Yager JY. Iron deï¬ciency: a cause of stroke in infants and children. Pediatric Neurology.1997; 16(1):50–53. https://doi.org/10.1016/S0887-8994(96)00290-1
Akins PT, Glenn S, Nemeth PM, Derdeyn CP. Carotid artery thrombus associated with severe iron –deficiency anemia and thrombocytosis. Stroke. 1996;27:1002-1005. https://doi.org/10.1161/01.STR.27.5.1002 PMid:8623090
Ibrahim R, Khan A, Shahzad Raza MK, Dabas R, Haynes E, Gandhi A, Majumder OL, Zaman M. Triad of iron deficiency anemia, severe thrombocytopenia and menorrhagia—a case report and literature review. Clinical medicine insights. Case reports. 2012;5:23. https://doi.org/10.4137/CCRep.S9329 PMid:22493563 PMCid:PMC3320130
Akoi N, Sakai T. Cerebral sinus thrombosis in patients with severe iron deficiency anemia due to myoma uteri. Acta Neurochir (Wien). 1989; 97:131-134. https://doi.org/10.1007/BF01772824
Baelum JK, Moe EE, Nybo M, Vinholt PJ. Venous Thromboembolism in Patients With Thrombocytopenia: Risk Factors, Treatment, and Outcome. Clinical and Applied Thrombosis/Hemostasis. 2017;23(4):345-50. https://doi.org/10.1177/1076029615613158 PMid:26512063
Mc Crae K. Immune thrombocytopenia with pulmonary embolism and deep vein thrombosis. The Haematologist. .2011; 8-6.
Ruggeri M, Tosetto A, Palandri F, et al. Thrombotic risk in patients with primary immune thrombocytopenia is only mildly increased and explained by personal and treatment-related risk factors. J Tgromb Haemost. 2014;12:1266-1273. https://doi.org/10.1111/jth.12636 PMid:24942752
Downloads
Published
How to Cite
Issue
Section
License
http://creativecommons.org/licenses/by-nc/4.0