A Patient with Multiple Keratinocytic Cancers (MKC): Uncommon Presentation in a Bulgarian Patient
DOI:
https://doi.org/10.3889/oamjms.2018.010Keywords:
skin cancer, surgery, island flap, basal cell carcinoma, squamous cell carcinomaAbstract
Keratinocyte skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common cancer occurring in people with fair skin, worldwide. Despite all known triggers, several suggested contributors are still investigated. We will focus our attention on the personal history of previous cancers and radiation exposure as occupational risk factors, as in the presented case. We report a patient, with multiple BCCs, and subsequent occurrence of a SCC on photo-exposed area of the face, as we want to emphasize the importance of strict following up of these patients, regarding the risk for developing new tumors in short periods of time, no matter if the triggering exposure factor is known from the history, or not. Although keratinocytes tumours are associated with the low mortality rate, we focus the attention on the fact, that the history of non-melanoma skin cancer is associated with increased mortality.Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Perera E., Gnaneswaran N, Staines C, Win AK, Sinclair R. Incidence and prevalence of non-melanoma skin cancer in Australia: A systematic review. Australas J Dermatol. 2015; 56(4):258-67. https://doi.org/10.1111/ajd.12282 PMid:25716064
Xiang F, Lucas R, Hales S, Neale R. Incidence of nonmelanoma skin cancer about ambient UV radiation in white populations, 1978-2012: empirical relationships. JAMA Dermatol. 2014; 150(10):1063-71. https://doi.org/10.1001/jamadermatol.2014.762 PMid:25103031
Skin cancer (non-melanoma) - risks factors and prevention. American Society of Clinical Oncology (ASCO). (2013, December). Cancer.Net. Alexandria, VA.: American Society of Clinical Oncology (ASCO). http://www.cancer.ca/en/cancer-information/cancer-type/skin-non-melanoma/risks/?region=sk#ixzz4qHIonl7C
Burgdorf W., Plewig G., Wolf H., Landtheler M. et al. Braun Falco's Dermatology. 3rd edition. Other syndromes associated with increased risk for Basal cell carcinoma. Springer, 2009: Chapter 95, p 1355. https://doi.org/10.1007/978-3-540-29316-3
Yanik EL, Pfeiffer RM, Freedman DM, Weinstock MA, Cahoon EK, Arron ST, Chaloux M, Connolly MK, Nagarajan P, Engels EA. The spectrum of Immune-Related Conditions Associated with Risk of Keratinocyte Cancers among Elderly Adults in the United States. Cancer Epidemiol Biomarkers Prev. 2017; 26(7):998-1007. https://doi.org/10.1158/1055-9965.EPI-17-0003 PMid:28377416
Marcil I, Stern RS. Risk of developing subsequent non-melanoma skin cancer in patients with a history of nonmelanoma skin cancer: a critical review of the literature and meta-analysis. Arch Dermatol. 2000; 136(12):1524-30. https://doi.org/10.1001/archderm.136.12.1524 PMid:11115165
Barton V, Armeson K1,2, Hampras S3, Ferris LK4, Visvanathan K5, Rollison D3, Alberg AJ. Nonmelanoma skin cancer and risk of all-cause and cancer-related mortality: a systematic review. Arch Dermatol Res. 2017; 309(4):243-251. https://doi.org/10.1007/s00403-017-1724-5 PMid:28285366
Smith V, Walton S. Treatment of facial Basal cell carcinoma: a review. J Skin Cancer. 2011; 2011:380371. https://doi.org/10.1155/2011/380371 PMid:21773034 PMCid:PMC3135095
Kwon KH, Lee DG, Koo SH, Jo MS, Shin H, Seul JH. Usefulness of v-y advancement flap for defects after skin tumor excision. Arch Plast Surg. 2012; 39(6):619-25. https://doi.org/10.5999/aps.2012.39.6.619 PMid:23233887 PMCid:PMC3518005
Downloads
Published
How to Cite
Issue
Section
License
http://creativecommons.org/licenses/by-nc/4.0