A Patient with Multiple Keratinocytic Cancers (MKC): Uncommon Presentation in a Bulgarian Patient


  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), General Skobelev 79, 1606 Sofia; Onkoderma - Policlinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia
  • Stanislav Philipov Sofiiski Universitet Sveti Kliment Okhridski Meditskinski Fakul'tet - Department of General and Clinical Pathology, Sofia
  • Anastasiya Atanasova Chokoeva Medical University Plovdiv - Dermatology and Venereology, Vasil Aprilov 15A, Plovdiv 4000
  • Uwe Wollina Städtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
  • Torello Lotti University G. Marconi of Rome - Dermatology and Venereology, Rome
  • Ilia Lozev Medical Institute of Ministry of Interior Department of General, Vascular and Abdominal Surgery, Sofia
  • Irina Yungareva Medical Institute of the Ministry of Interior - Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia
  • Georgi Konstantinov Maximov ”Onkoderma” - Policlinic for Dermatology and Dermatologic Surgery, Sofia




skin cancer, surgery, island flap, basal cell carcinoma, squamous cell carcinoma


Keratinocyte skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common cancer occurring in people with fair skin, worldwide. Despite all known triggers, several suggested contributors are still investigated. We will focus our attention on the personal history of previous cancers and radiation exposure as occupational risk factors, as in the presented case. We report a patient, with multiple BCCs, and subsequent occurrence of a SCC on photo-exposed area of the face, as we want to emphasize the importance of strict following up of these patients, regarding the risk for developing new tumors in short periods of time, no matter if the triggering exposure factor is known from the history, or not.  Although keratinocytes tumours are associated with the low mortality rate, we focus the attention on the fact, that the history of non-melanoma skin cancer is associated with increased mortality.


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How to Cite

Tchernev G, Philipov S, Chokoeva AA, Wollina U, Lotti T, Lozev I, Yungareva I, Maximov GK. A Patient with Multiple Keratinocytic Cancers (MKC): Uncommon Presentation in a Bulgarian Patient. Open Access Maced J Med Sci [Internet]. 2018 Jan. 13 [cited 2023 Sep. 27];6(1):120-2. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.010

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