Mucoepidermoid Carcinoma (MEC) of Parotid Gland with Massive Cutaneous Involvement: Bilateral Pedicle Advancement Flap (U - Plasty) As Adequate Surgical Approach

Ilia Lozev; Sonya Ruseva; Ivan Pidakev; JosÃ© Carlos Cardoso; Uwe Wollina; Torello Lotti; Georgi Konstantinov Maximov; Ivan Terziev; Georgi Tchernev

doi:10.3889/oamjms.2018.014

Authors

Ilia Lozev Medical Institute of Ministry of Interior Department of General, Vascular and Abdominal Surgery, Sofia
Sonya Ruseva â€œOnkodermaâ€ - Policlinic for Dermatology, Venereology and Dermatologic Surgery, Sofia
Ivan Pidakev Medical Institute of Ministry of Interior Department of General, Vascular and Abdominal Surgery, Sofia
JosÃ© Carlos Cardoso Dermatology Department, Coimbra Hospital and University Center, Praceta Mota Pinto, Coimbra
Uwe Wollina StÃ¤dtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
Torello Lotti University G. Marconi of Rome - Dermatology and Venereology, Rome
Georgi Konstantinov Maximov â€œOnkodermaâ€ - Policlinic for Dermatology, Venereology and Dermatologic Surgery, Sofia
Ivan Terziev Department of Common and Clinical Pathology, University Hospital Tsaritsa Ioana, Sofia
Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), General Skobelev 79, 1606 Sofia; Onkoderma - Policlinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia

DOI:

https://doi.org/10.3889/oamjms.2018.014

Keywords:

mucoepidermoid ca, carcinoma, U plasty, radiation, outcome

Abstract

Neoplasms of the major and minor salivary glands are morphologically and a clinically diverse group of neoplasms which lead the clinician to diagnostic and management challenges. This article aims to report a case of mucoepidermoid carcinoma in 83 â€“ year - old woman who presented in the dermatology clinic with a tumour mass in the left auricular area. The patient complained of pain and abnormal bleeding of the mass. The lesion was examined, and surgical treatment was performed. A tumour was extirpated, and partial resection of both the parotid gland and the sternocleidomastoid muscle was done. Lymphatic dissection was performed. Post recovery was uneventful with no functional defects and abnormalities. The pathohistological result confirmed the diagnosis of mucoepidermoid carcinoma of the parotid gland with massive infiltration of the skin and the subcutaneous tissue. Lymph nodules with total metastasis of mucoepidermoid carcinoma and capsular invasion were additionally presented. Postoperative radiation therapy was planned.

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References

Ho K, Lin H, Yen Chu and Y. An overview of the rare parotid gland cancer. Head and Neck Oncol. 2011; 3(1):40. https://doi.org/10.1186/1758-3284-3-40 PMid:21917153 PMCid:PMC3197557

Kofi D, Boahene O, Olsen K, Lewis J. Mucoepidermoid Carcinoma of the parotid gland. Arch Otolaryngol. Head Neck Surg. 2004; 130(7):849 - 856. https://doi.org/10.1001/archotol.130.7.849 vPMid:15262762

Luna MA. Salivary mucoepidermoid carcinoma: revisited. Adv Anat Pathol. 2006; 13:293 - 307. https://doi.org/10.1097/01.pap.0000213058.74509.d3 PMid:17075295

Kokemueller H, Brueggemann N, Swennen G, Eckardt A. Mucoepidermoid carcinoma of the salivary glands, clinical review of 42 cases. Oral Oncol. 2005; 41(3):10. https://doi.org/10.1016/j.oraloncology.2004.01.017

Guevara-Canales J, Morales-Vadillo R, Guzman-Arias G, Cava - Vergiu C, Guerra - Miller H, Montes- Gil J. Mucoepidermoid carcinoma of the salivary glands. A retrospective study of 51 cases and review of the literature. Acta Odontol Latinoam. 2016; 29(3):230 - 238. PMid:28383603

Nance MA, Seethala RR, Wang Y, Chiosea SI, Myers EN, Johnson JT, Lai SY. Treatment and survival outcomes based on histologic grading in patients with head and neck mucoepidermoid carcinoma. Cancer. 2008; 113(8):2082 - 9. https://doi.org/10.1002/cncr.23825 PMid:18720358 PMCid:PMC2746751

Darling R, McCammon S, Resto V, Quin F. Carcinoma in head and neck. Grand Rounds Presentation, The University of Texas Medical Branch at Galveston, Department of Otolaryngology. 2014; 5: 1 - 10.

Arrangoiz R, Papavasiliuo P, Sarcu D, Galloway T, Ridge J, Lango M. Journal of Cancer Treatment and Research. Current thinking on malignant salivary gland neoplasms. 2013; 1(1):8 - 24.

Olsen M, Mitchell A, Milles E. Postoperative Radiation Therapy for Parotid Mucoepidermoid Cancer. Case Rep Oncol Med. 2014; 1 - 4. https://doi.org/10.1155/2014/345128 PMid:25580323 PMCid:PMC4279126

Kaszuba SM, Zafereo ME, Rosenthal DI, El -Naggar AK, Weber RS.Effect of initial treatment on disease outcome for patients with submandibular gland carcinoma. Arch Otolaryngol Head Neck Surg. 2007; 133(6):546 - 50. https://doi.org/10.1001/archotol.133.6.546 PMid:17576904

Frankenthaler RA, El-Naggar AK, Ordonez NG. High correlation with survival of proliferating nuclear antigen expression in mucoepidermoid carcinoma of the parotid gland. Otolaryngol Head Neck Surg. 1994; 11:460 - 466. https://doi.org/10.1177/019459989411100412 PMid:7936679

Barnes L. Metastases to the Head and Neck: an overview. Head and Neck Pathol. 2009; 3(3):217 - 224. https://doi.org/10.1007/s12105-009-0123-4 PMid:20596975 PMCid:PMC2811631

Yook JI, Lee SA, Chun YC, Huh J, Cha IH, Kim J. The myoepithelial cell differentiation of mucoepidermoid carcinoma in a collagen gel-based coculture model. J Oral Pathol Med. 2004; 33:237 - 42. https://doi.org/10.1111/j.0904-2512.2004.00056.x PMid:15061712

Purohit J, Desai V, Sharma R, Sharma A. Mucoepidermoid carcinoma of parotid gland: A case report. 2015; 2(2):106 -109.