Disseminated Porokeratosis with Idiopathic Thrombocytopenia - Case Report and Literature Review of Porokeratosis and Related Disorders

Authors

  • Anastasiya Atanasova Chokoeva Medical University Plovdiv, Dermatology and Venereology, Vasil Aprilov 15A, Plovdiv 4000
  • Uwe Wollina Städtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
  • Torello Lotti University G. Marconi of Rome - Dermatology and Venereology, Rome
  • Georgi Konstantinov Maximov ”Onkoderma” - Policlinic for Dermatology and Dermatologic Surgery, Sofia
  • Ilia Lozev Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia
  • Georgi Tchernev Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia; ”Onkoderma” - Policlinic for Dermatology and Dermatologic Surgery, Sofia

DOI:

https://doi.org/10.3889/oamjms.2018.017

Keywords:

Porokeratosis, Acitretin, Betamethasone, Outcome, Therapy, Cryosurgery

Abstract

BACKGROUND: Porokeratosis is characterised by one or more atrophic patches surrounded by a distinctive peripheral keratotic ridge, typically found on sun-exposed areas, with several clinical variants and typical histological findings. Despite ultraviolet radiation, varies antibody - related autoimmune disease treated with systemic steroids and other immunosuppressive conditions such as chronic liver disease, HIV and organ transplantations have been implicated in its etiopathology.

CASE REPORT: We present a case of porokeratosis, associated with idiopathic thrombocytopenia in 74 - year old, otherwise healthy male patient, as we discuss the previously reported associated disorders.

CONCLUSION: Regarding all of the polymorphism of clinical presentation, associated disorders and treatment responses, we could conclude that disseminated porokeratosis is still an unknown well disorder, which will continue to surprise the physicians in future. The screening and follow up of the patients is mandatory in all cases because as we see, porokeratosis has multiple unexpected faces, which require circumstantial clinical and paraclinical behaviour.

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References

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Published

2018-01-13

How to Cite

1.
Chokoeva AA, Wollina U, Lotti T, Maximov GK, Lozev I, Tchernev G. Disseminated Porokeratosis with Idiopathic Thrombocytopenia - Case Report and Literature Review of Porokeratosis and Related Disorders. Open Access Maced J Med Sci [Internet]. 2018 Jan. 13 [cited 2021 Apr. 11];6(1):139-42. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.017

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