Van Lohuizen Syndrome – A Case Report with a Diagnostic Delay of Four Years


  • Uwe Wollina Städtisches Klinikum Dresden, Department of Dermatology and Allergology, 01067 Dresden
  • Katlein França Department of Dermatology and Cutaneous Surgery, Department of Psychiatry & Behavioral Sciences; Institute for Bioethics and Health Policy, University of Miami Miller School of Medicine, Miami, FL
  • Torello Lotti Centro Studi per la Ricerca Multidisciplinare e Rigenerativa, Guglielmo Marconi University, Rome
  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), General Skobelev 79, 1606 Sofia; Onkoderma Policlinic for Dermatology and Dermatologic Surgery, Sofia



Cutis marmorata telangiectatica congenita, Van Lohuizen syndrome, vascular-cutaneous disorders


BACKGROUND: Cutis marmorata telangiectatic congenital or Van Lohuizen syndrome is a rare vascular disorder that may be associated with other congenital malformations. Around 300 cases have been reported so far.

CASE REPORT: We present a 4-year-old girl with Van Lohuizen syndrome of the leg, but without any other malformations.

CONCLUSION: Neonatal lupus erythematosus may resemble congenital vasculopathy, but histopathology and immune-serology are characteristic.


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How to Cite

Wollina U, França K, Lotti T, Tchernev G. Van Lohuizen Syndrome – A Case Report with a Diagnostic Delay of Four Years. Open Access Maced J Med Sci [Internet]. 2018 Jan. 2 [cited 2021 Apr. 12];6(1):74-5. Available from:

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