Epidermoid Cysts – A Wide Spectrum of Clinical Presentation and Successful Treatment by Surgery: A Retrospective 10-Year Analysis and Literature Review


  • Uwe Wollina Städtisches Klinikum Dresden, Department of Dermatology and Allergology, 01067 Dresden
  • Dana Langner Stadtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, Sofia; Onkoderma Policlinic for Dermatology and Dermatologic Surgery, Sofia
  • Katlein França Department of Dermatology and Cutaneous Surgery, Department of Psychiatry & Behavioral Sciences; Institute for Bioethics and Health Policy, University of Miami Miller School of Medicine, Miami, FL
  • Torello Lotti University of Rome G. Marconi, Institute of Dermatology, Rome 00186




Epidermoid cysts, Pathogenesis, Skin, Surgery, Gardner syndrome, Lowe syndrome


Epidermoid cysts are common benign lesions of hair-bearing, and less often glabrous skin. They can also occur in oral mucosa and internal organs. In case of cutaneous lesions, an epidermal punctum is a clinical diagnostic hallmark. The clinical presentation is variable leading to some differential diagnoses. Diagnosis of epidermoid cysts needs histopathological confirmation – not only of the potential of malignant transformation. The treatment of choice is surgery. We report a retrospective analysis of 2159 epidermoid cysts treated surgically. Most of the cases can be performed under local anaesthesia. The complication rate of 2.2% is low. To avoid relapses, the cyst wall has to be removed completely. Rare genetic disorders with multiple cysts are Gardner and Lowe syndrome.


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How to Cite

Wollina U, Langner D, Tchernev G, França K, Lotti T. Epidermoid Cysts – A Wide Spectrum of Clinical Presentation and Successful Treatment by Surgery: A Retrospective 10-Year Analysis and Literature Review. Open Access Maced J Med Sci [Internet]. 2018 Jan. 10 [cited 2023 Dec. 6];6(1):28-30. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.027

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