Ulcerating Lichen Planopilaris – Successful Treatment by Surgery

Authors

  • Uwe Wollina Städtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
  • Birgit Heinig Städtisches Klinikum Dresden - Center of Physical and Rehabilitative Medicine, Dresden
  • André Koch Städtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden
  • Andreas Nowak Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany - Department of Anesthesiology & Intensive Care Medicine, Emergency Medicine & Pain Management, Dresden
  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, Sofia; Onkoderma, Policlinic for Dermatology and Dermatologic Surgery, Sofia
  • Katlein França Department of Dermatology and Cutaneous Surgery, Department of Psychiatry & Behavioral Sciences; Institute for Bioethics and Health Policy, University of Miami Miller School of Medicine, Miami, FL
  • Torello Lotti University of Rome G. Marconi, Institute of Dermatology, Rome 00186

DOI:

https://doi.org/10.3889/oamjms.2018.029

Keywords:

Lichen planus, Lichen planopilaris, Scalp ulceration, Surgery, Combined tissue advancement and extension

Abstract

Lichen planus is a T-cell mediated autoimmune disorder affecting the skin and mucous membranes. Ulcerating lichen planus is uncommon mostly on oral and genital mucosa but not skin. Lichen planopilaris, however, is a subtype of lichen planus affection hair follicles and leading to permanent scarring alopecia. We report a case of lichen planopilaris of the scalp with multiple alopecic patches ulceration – a hitherto unreported clinical feature. The patient was treated surgically, and the defect could be closed by combined tissue advancement and extension.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Tan E, Martinka M, Ball N, Shapiro J. Primary cicatricial alopecias: clinicopathology of 112 cases. J Am Acad Dermatol. 2004; 50(1):25-32. https://doi.org/10.1016/j.jaad.2003.04.001 PMid:14699361

Siah TW, Shapiro J. Scarring alopecias: a trichologic emergency. Semin Cutan Med Surg. 2015; 34(2):76-80. https://doi.org/10.12788/j.sder.2015.0130 PMid:26176284

Kossard S. Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution. Arch Dermatol. 1994; 130(6):770-4. https://doi.org/10.1001/archderm.1994.01690060100013 PMid:8002649

Cerqueira ER, Valente N, Sotto MN, Romiti R. Comparative analysis of immunopathological features of lichen planopilaris and female patients with frontal fibrosing alopecia. Int J Trichology. 2016; 8(4):197-202. https://doi.org/10.4103/0974-7753.203179 PMid:28442882 PMCid:PMC5387886

Baibergenova A, Donovan J. Lichen planopilaris: update on pathogenesis and treatment. Skinmed. 2013; 11(3):161-5.PMid:23930355

Meinhard J, Stroux A, Lünnemann L, Vogt A, Blume-Peytavi U. Lichen planopilaris: Epidemiology and prevalence of subtypes - a retrospective analysis in 104 patients. J Dtsch Dermatol Ges. 2014; 12(3):229-35, 229-36.

Soares VC, Mulinari-Brenner F, Souza TE. Lichen planopilaris epidemiology: a retrospective study of 80 cases. An Bras Dermatol. 2015; 90(5):666-70. https://doi.org/10.1590/abd1806-4841.20153923 PMid:26560212 PMCid:PMC4631232

Assouly P, Reygagne P. Lichen planopilaris: update on diagnosis and treatment. Semin Cutan Med Surg. 2009; 28(1):3-10. https://doi.org/10.1016/j.sder.2008.12.006 PMid:19341936

Conrotto D, Carbone M, Carrozzo M, Arduino P, Broccoletti R, Pentenero M, Gandolfo S. Ciclosporin vs. clobetasol in the topical management of atrophic and erosive oral lichen planus: a double-blind, randomized controlled trial. Br J Dermatol. 2006; 154(1):139-45. https://doi.org/10.1111/j.1365-2133.2005.06920.x PMid:16403107

Lajevardi V, Ghodsi SZ, Goodarzi A, Hejazi P, Azizpour A, Beygi S. Comparison of systemic mycophenolate mofetil with topical clobetasol in lichen planopilaris: a parallel-group, assessor- and analyst-blinded, randomized controlled trial. Am J Clin Dermatol. 2015; 16(4):303-11. https://doi.org/10.1007/s40257-015-0122-z PMid:25786714

Fertig R, Tosti A. Frontal fibrosing alopecia treatment options. Intractable Rare Dis Res. 2016; 5(4):314-5. https://doi.org/10.5582/irdr.2016.01065 PMid:27904832 PMCid:PMC5116872

Weston G, Payette M. Update on lichen planus and its clinical variants. Int J Women's Dermatol. 2015; 1(3):140-9. https://doi.org/10.1016/j.ijwd.2015.04.001 PMid:28491978 PMCid:PMC5418875

Wollina U, Konrad H, Graefe T. Ulcerative lichen planus: a case responding to recombinant platelet-derived growth factor BB and immunosuppression. Acta Derm Venereol. 2001; 81(5):364-5. https://doi.org/10.1080/000155501317140115 PMid:11800147

Goucha S, Khaled A, Bennani Z, Rammeh S, Zéglaoui F, Zermani R, Fazaa B. Erosive lichen planus of the soles: Effective response to prednisone. Dermatol Ther (Heidelb). 2011; 1(1):20-4.https://doi.org/10.1007/s13555-011-0005-z PMid:22984660 PMCid:PMC3437639

Garrido Colmenero C, Martín Castro A, Valenzuela Salas I, Martínez García E, Blasco Morente G, Tercedor Sánchez J. Squamous cell carcinoma in lichen planopilaris. J Dermatol Case Rep. 2013; 7(3):84-7. https://doi.org/10.3315/jdcr.2013.1147 PMid:24133562 PMCid:PMC3797015

Wollina U, Bayyoud Y, Krönert C, Nowak A. Giant epithelial malignancies (Basal cell carcinoma, squamous cell carcinoma): a series of 20 tumors from a single center. J Cutan Aesthet Surg. 2012; 5(1):12-9. https://doi.org/10.4103/0974-2077.94328

PMid:22557850 PMCid:PMC3339122

Published

2018-01-10

How to Cite

1.
Wollina U, Heinig B, Koch A, Nowak A, Tchernev G, França K, Lotti T. Ulcerating Lichen Planopilaris – Successful Treatment by Surgery. Open Access Maced J Med Sci [Internet]. 2018 Jan. 10 [cited 2021 Apr. 11];6(1):96-8. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.029

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>