Arthrospira Platensis – Potential in Dermatology and Beyond


  • Uwe Wollina Städtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
  • Cristiana Voicu Polisano Clinic - Department of Dermatology and Venereology, Piscului 16, Corbeanca, Ilfov 077065
  • Serena Gianfaldoni University G. Marconi of Rome - Dermatology and Venereology, Rome
  • Torello Lotti University G. Marconi of Rome - Dermatology and Venereology, Rome
  • Katlein França Department of Dermatology and Cutaneous Surgery, Department of Psychiatry & Behavioral Sciences; Institute for Bioethics and Health Policy, University of Miami Miller School of Medicine, Miami, FL
  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, Sofia; Onkoderma, Policlinic for Dermatology and Dermatologic Surgery, Sofia



Microalgae, Arthrospira platensis, Calcium spirulan, Gamma-linolenic acid, Phycocyanin


The search for natural products with benefits for health in general and of potential for treating human disease has gained wider interest world-wide. Here, we analyse current data on the microalga Arthrospira platensis (AP), that has been used in nutrition since ancient times in Fare East and African communities, for medical purposes with a focus on dermatology. Extracts of AP have been investigated in vitro and in vivo. The alga is rich in proteins, lipopolysaccharides and gamma-linolenic acid. AP extracts, phycocyanin compounds and polysaccharide calcium spirulan (Ca-SP) have been evaluated in various models. It could be demonstrated, that AP has significant antioxidant activity, prevents viruses from entry into target cells and inhibits the colonisation of wounds by multi-resistant bacteria. Furthermore, anti-cancer activity was documented in models of oral cancer, melanoma, and UV-induced non-melanoma skin cancer.


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How to Cite

Wollina U, Voicu C, Gianfaldoni S, Lotti T, França K, Tchernev G. Arthrospira Platensis – Potential in Dermatology and Beyond. Open Access Maced J Med Sci [Internet]. 2018 Jan. 10 [cited 2021 May 15];6(1):176-80. Available from:

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