Acrocyanosis â€“ A Symptom with Many Facettes

Uwe Wollina; AndrÃ© Koch; Dana Langner; Gesina Hansel; Birgit Heinig; Torello Lotti; Georgi Tchernev

doi:10.3889/oamjms.2018.035

Authors

Uwe Wollina StÃ¤dtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
AndrÃ© Koch StÃ¤dtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
Dana Langner StÃ¤dtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
Gesina Hansel StÃ¤dtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
Birgit Heinig StÃ¤dtisches Klinikum Dresden - Center of Physical and Rehabilitative Medicine, Dresden
Torello Lotti University G. Marconi of Rome - Dermatology and Venereology, Rome
Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, Sofia; Onkoderma, Policlinic for Dermatology and Dermatologic Surgery, Sofia

DOI:

https://doi.org/10.3889/oamjms.2018.035

Keywords:

Acrocyanosis, hands and feet, vascular disorders, Raynaud syndrome, Connective tissue diseases, Adverse drug reactions, Tumors

Abstract

Acrocyanosis is an uncommon complaint belonging to the acro-syndromes. It typically presents with coolness and bluish discolourations of hands, feet, ears, nose, lips and nipple. The most frequently affected parts of the body are the hands. This review discusses physical factors, vascular disorders, infectious diseases, haematological disorders, solid tumours genetic disorders, drugs, eating disorders, and spinal disease presenting as or leading to acrocyanosis.

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