A “Yellow Submarine” in Dermoscopy


  • Francesca Satolli Dermatology, Via Gramsci 14, Parma, Parma 43126
  • Miriam Rovesti Dermatology, Via Gramsci 14, Parma, Parma 43126
  • Alfredo Zucchi Dermatology, Via Gramsci 14, Parma, Parma 43126
  • Marco Gandolfi Dermatology, Via Gramsci 14, Parma, Parma 43126
  • Claudio Feliciani Dermatology, Via Gramsci 14, Parma, Parma 43126
  • Georgi Tchernev ”Onkoderma”- Policlinic for Dermatology and Dermatologic Surgery, Sofia; Medical Institute of Ministry of Interior (MVR-Sofia), Department of Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606 Sofia
  • Uwe Wollina Städtisches Klinikum Dresden, Department of Dermatology and Allergology, 01067 Dresden
  • Serena Gianfaldoni University G. Marconi of Rome - Dermatology and Venereology, University G. Marconi of Rome, Rome 00192
  • Torello Lotti 6University of Rome G. Marconi, Rome 00186, Institute of Dermatology




histiocytic sarcoma, dermoscopy, yellow colour, CD68, WHO classification lymphomas


BACKGROUND: Histiocytic sarcoma (HS) is an extremely rare, non-Langerhans cell tumor. HS affects especially adults, its etiology is unknown yet. Skin could be interested by papules or nodules, single or multiple.  

CASE REPORT: A Caucasian man in his late 40s came to our clinic for a naevi evaluation. During the visit, a rose papulonodular lesion was observed in the lumbar region. This lesion was completely asymptomatic, and it had been there for an indefinite period. The clinical evaluation revealed that the lesion appeared elevated, of 9 x 15 mm in dimension, symmetrical and of a homogeneous pinkish colour. The videodermoscopical evaluation revealed a homogeneous yellow central pattern, polymorphic vessels, an eccentric peripheral pigmentation and a white collar. An excisional biopsy was performed. The morphology and the expression of CD163, CD68 and/or lysozyme to the immunophenotypic analysis, revealed the true nature of the lesion.

CONCLUSION: HS is usually diagnosed at an already advanced clinical stage and it has a high mortality rate even today. Dermoscopy, showing a yellow and distributed homogeneously colour, can facilitate its hard diagnosis.


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How to Cite

Satolli F, Rovesti M, Zucchi A, Gandolfi M, Feliciani C, Tchernev G, Wollina U, Gianfaldoni S, Lotti T. A “Yellow Submarine” in Dermoscopy. Open Access Maced J Med Sci [Internet]. 2018 Jan. 7 [cited 2023 Sep. 27];6(1):76-8. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.039

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