Vitiligo in Children: A Better Understanding of the Disease

Serena Gianfaldoni; Georgi Tchernev; Uwe Wollina; Jacopo Lotti; Francesca Satolli; Katlein FranÃ§a; Miriam Rovesti; Torello Lotti

doi:10.3889/oamjms.2018.040

Authors

Serena Gianfaldoni University G. Marconi of Rome, Dermatology and Venereology, Rome 00192
Georgi Tchernev Medical Institute of the Ministry of Interior, Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia; Onkoderma, Private Clinic for Dermatologic Surgery, Sofia
Uwe Wollina StÃ¤dtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen
Jacopo Lotti University G. Marconi of Rome, Dept. of Nuclear, Subnuclear and Radiation Physics, Via Plinio 44, Rome 00193
Francesca Satolli Department of Dermatology, University of Parma, Via Gramsci 14, Parma, Parma 43126,
Katlein FranÃ§a University of Miami School of Medicine, 1400 NW 10th Avenue, Miami, Florida 33136-1015
Miriam Rovesti Department of Dermatology, University of Parma, Via Gramsci 14, Parma, Parma 43126
Torello Lotti University G. Marconi of Rome, Dermatology and Venereology, Rome 00192

DOI:

https://doi.org/10.3889/oamjms.2018.040

Keywords:

vitiligo, children, genetic background, trigger factor, environmental stress, clinic, comorbidities

Abstract

Vitiligo is an important skin disease of childhood. The authors briefly discuss the etiopathobiology, clinics and comorbidities of the disease.

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References

HercogovÃ¡ J, Schwartz RA, Lotti TM. Classification of vitiligo: a challenging endeavor. Dermatol Ther. 2012; 25(Suppl 1):S10-6. https://doi.org/10.1111/dth.12010 PMid:23237033

Halder RM, Grimes PE, Cowan CA, et Al Childhood vitiligo. J Am Acad Dermatol. 1987; 16:948â€“54. https://doi.org/10.1016/S0190-9622(87)70119-4

Manzoni AP, Weber MB, Nagatomi AR et Al. Assessing depression and anxiety in the caregivers of pediatric patients with chronic skin disorders. An Bras Dermatol. 2013; 88(6):894-9. https://doi.org/10.1590/abd1806-4841.20131915 PMid:24474096 PMCid:PMC3900338

Lee BW, Schwartz RA, HercogovÃ¡ J, Valle Y, Lotti TM. Vitiligo road map. Dermatol Ther. 2012; 25(Suppl 1):S44-56. https://doi.org/10.1111/dth.12006 PMid:23237038

Jin Y, Ferrara T, Gowan K, et al. Next-generation DNA re-sequencing identifies common variants of TYR and HLA-A that modulate the risk of generalized vitiligo via antigen presentation. J Invest Dermatol. 2012; 132(6):1730â€“1733. https://doi.org/10.1038/jid.2012.37 PMid:22402439 PMCid:PMC3513338

Zhang XJ, Chen JJ, Liu JB. The genetic concept of vitiligo. J Dermatol Sci. 2005; 39(3):137â€“146. 73.

Alkhateeb A, Fain PR, Thody A et Al. Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res. 2003; 16:208-14. https://doi.org/10.1034/j.1600-0749.2003.00032.x PMid:12753387

Shah AA, Sinha AA. Oxidative stress and autoimmune skin disease. Eur J Dermatol. 2013; 23(1):5-13. PMid:23420016

Gianfaldoni S, Zanardelli M, Lotti T. New technology for Vitiligo repigmentation. Ceska dermato-venerologie. 2014; (4):39-41.

Prignano F, Pescitelli L, Becatti M, et al. Ultrastructural and functional alterations of mitochondria in perilesional vitiligo skin. J Dermatol Sci. 2009; 54:157â€“67. https://doi.org/10.1016/j.jdermsci.2009.02.004 PMid:19282153

Lee DY, Kim CR, Lee JH. Trichrome vitiligo in segmental type. Photodermatol Photoimmunol Photomed. 2011; 27(2):111-112. https://doi.org/10.1111/j.1600-0781.2011.00572.x PMid:21392115

Chandrashekar L. Dermatoscopy of blue vitiligo. Clin Exp Dermatol. 2009; 34(5):e125-126. https://doi.org/10.1111/j.1365-2230.2008.03155.x PMid:19438538

Huggins RH, Janusz CA, Schwartz RA. Vitiligo a sign of systemic disease. Indian J Dermatol Venereol Leprol. 2006; 72:68-71. https://doi.org/10.4103/0378-6323.19730 PMid:16481722

Ezzedine K, Lim HW, Suzuki T et Al. Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference. Pigment Cell Melanoma Res. 2012; 25(3): E1â€“13. https://doi.org/10.1111/j.1755-148X.2012.00997.x PMid:22417114 PMCid:PMC3511780

Lotti T, D'Erme AM. Vitiligo as a systemic disease. Clin Dermatol. 2014; 32(3):430-434. https://doi.org/10.1016/j.clindermatol.2013.11.011 PMid:24767192

Pietrzak A, BartosiÅ„ska J, HercogovÃ¡ J et Al. Metabolic syndrome in vitiligo. Dermatol Ther. 2012; 25(Suppl 1):S41-43. https://doi.org/10.1111/dth.12012 PMid:23237037