Ovarian Strumal Carcinoid Tumour: Case Report

Vesna S. Antovska; Iskra Krstevska; Milka Trajanova; Irena Gosheva; Jasmina Chelebieva; Irina Prodanova

doi:10.3889/oamjms.2018.138

Authors

Vesna S. Antovska Department for Urogynaecology and Pelvic Floor Disorders, University Clinic for Gynecology and Obstetrics, Skopje
Iskra Krstevska Department for Urogynaecology and Pelvic Floor Disorders, University Clinic for Gynecology and Obstetrics, Skopje
Milka Trajanova Department for Urogynaecology and Pelvic Floor Disorders, University Clinic for Gynecology and Obstetrics, Skopje
Irena Gosheva Department for Urogynaecology and Pelvic Floor Disorders, University Clinic for Gynecology and Obstetrics, Skopje http://orcid.org/0000-0001-5950-4340
Jasmina Chelebieva Department for Urogynaecology and Pelvic Floor Disorders, University Clinic for Gynecology and Obstetrics, Skopje
Irina Prodanova PHI Histolab, Diagnostic Laboratory for Cytology and Histopathology, Skopje

DOI:

https://doi.org/10.3889/oamjms.2018.138

Keywords:

Ovarian teratoma, Strumal carcinoid, Carcinoid syndrome

Abstract

BACKGROUND: Ovarian strumal carcinoid is a germ cell tumour characterised by a mixture of thyroid tissue and carcinoid. Ovarian struma is a very rare occurrence with 0.3-1% incidence of all ovarian tumours and 3% of mature teratomas. Primary carcinoid ovarian tumours are still uncommon as a part of mature teratoma or mucinous cystadenoma. There are four major variants of a carcinoid tumour: insular, trabecular, strumal and mucinous. A strumal carcinoid is an unusual form of ovarian teratoma composed of an intimate admixture of thyroid/carcinoid tissues.

CASE REPORT: This is a case report of a 59-year old woman with a 5-year clinical history of perimenopausal uterine bleeding and three explorative curettages. Gynaecological and ultrasound examinations revealed ovarian enlargement with a diameter of 50 mm with hypoechoic zones suspected of benign teratoma. The diagnostic test such as Ca-125, AFP, free-T4 and TSH was in normal range. A smooth, solid right ovarian 50 an mm-size tumour, as well as small amount of fluid in the Douglas pouch, was found during the total abdominal hysterectomy, bilateral salpingo-oophorectomy and staging biopsy.Â The histopathology revealed teratoma with strumal carcinoid tumour IA stage according to AJCC 2010 of the right ovary and negative cytopathology of the fluid from the Douglas pouch. On the postoperative 2-year control, the patient was tumour free, and Ca-125, free-T4 and TSH were in normal range.

CONCLUSION: We would like to point out those specific diagnostic tools, such as ultrasound and Ca-125 have low specificity and sensitivity in detection of this rare ovarian malignancy.

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Author Biography

Irena Gosheva, Department for Urogynaecology and Pelvic Floor Disorders, University Clinic for Gynecology and Obstetrics, Skopje

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