Nevus Blue as a Sporadic Finding in a Patient with a Blue Toe?

Authors

  • Ivanka Temelkova Medical Institute of the Ministry of Interior (MVR-Sofia), Dermatology, Venereology and Dermatologic Surgery, Sofia
  • Konstantin Stavrov Medical Institute of the Ministry of Interior (MVR-Sofia), Dermatology and Dermatosurgery, Sofia
  • Irina Yungareva Medical Institute of the Ministry of Interior (MVR-Sofia), Dermatology, Venereology and Dermatologic Surgery, Sofia
  • Uwe Wollina Städtisches Klinikum Dresden, Department of Dermatology and Allergology, Dresden
  • Hristo Mangarov Medical Institute of the Ministry of Interior (MVR-Sofia), Dermatology, Venereology and Dermatologic Surgery, Sofia
  • Atanas Radinoff Department of Clinical Hematology, University Multiprofile Hospital for Active Treatment “Sveti Ivan Rilski”, 15, Acad. Ivan Geshov Blvd., Sofia 431
  • Tanya Naskova Popova Department of Clinical Hematology, University Multiprofile Hospital for Active Treatment “Sveti Ivan Rilski”, 15, Acad. Ivan Geshov Blvd., Sofia 431
  • Georgi Tchernev Medical Institute of the Ministry of Interior (MVR-Sofia), Dermatology, Venereology and Dermatologic Surgery, Sofia; Onkoderma - Policlinic for Dermatology and Dermatologic Surgery, Sofia

DOI:

https://doi.org/10.3889/oamjms.2018.228

Keywords:

blue nevus, cyanotic toe, microembolism, vasodilatation, sentinel lymph nodes, observation

Abstract

BACKGROUND: Blue nevus is an interesting finding, which aetiology and risk of locoregional and distant metastasis have not yet been fully clarified. It may be inherited or acquired, with sporadic cases usually presented as solitary lesions. It is often localised in the area of the head and less often on the arms, legs or trunk. Blue nevi are formations with relatively low but still possible potential for switching to melanoma.

CASE REPORT: The patient we described was hospitalised for pronounced cyanosis of the small toe of the right foot, accompanied by painful symptoms at rest and pain symptoms for a few weeks. Using inpatient paraclinical and instrumental tests, the patient was diagnosed with cholesterol microembolism. During the dermatological examination, blue nevus on the contralaterally localised limb was also diagnosed as a sporadic finding. According to the patient’s medical history, the finding had existed for many years, but in the last few months, the patient has observed growth and progression in the peripheral zone of the nevus without any additional clinical symptoms.

CONCLUSION: Due to the risk of progression to melanoma, the lesion was removed by radical excision, and the defect was closed by tissue advancement flap.

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References

Zembowicz A. Blue nevi and related tumours. Clin Lab Med. 2017; 37(3):401-415. https://doi.org/10.1016/j.cll.2017.05.001 PMid:28802492

Bogart M, Bivens M, Patterson W, Russell A. Blue nevi: a case report and review of the literature. Cutis. 2007; 80(1):42-4. PMid:17725063

Daltro L, Yaegashi L, Freitas R, Fantini B, Souza C. Atypical cellular blue nevus or malignant blue nevus? An Bras Dermatol. 2017; 92(1): 110–112. https://doi.org/10.1590/abd1806-4841.20174502 PMid:28225968 PMCid:PMC5312190

Griewank K, Müller H, Jackett A, Emberger M, Möller I, van de Nes J, Zimmer L, Livingstone E, Wiesner T, Scholz S, Cosgarea I, Sucker A, Schimming T, Hillen U, Schilling B, Paschen A, Reis H, Mentzel T, Kutzner H, Rütten A, Murali R, Scolyer R, Schadendorf D. SF3B1 and BAP 1 mutations in blue nevus-like melanoma. Mod Pathol. 2017; 30(7):928-939. https://doi.org/10.1038/modpathol.2017.23 PMid:28409567

Oliveira AH, Shiraishi AF, Kadunc BV, Sotero PD, Stelini RF, Mendes C. Blue nevus with satellitosis: case report and literature review. Anais brasileiros de dermatologia. 2017; 92(5):30-3. https://doi.org/10.1590/abd1806-4841.20175267 PMid:29267439 PMCid:PMC5726670

Scheller K, Scheller C, Becker S, Holzhausen J, Schubert J. Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: a case report and review of the literature. J Craniomaxillofac Surg. 2010; 38(8):601-4. https://doi.org/10.1016/j.jcms.2010.01.008 PMid:20223677

Jonjić N, Dekanić A, Glavan N, Massari L, Grahovac B. Cellular Blue Nevus Diagnosed following Excision of Melanoma: A Challenge in Diagnosis. Case Rep Pathol. 2016; 2016: 8107671. https://doi.org/10.1155/2016/8107671

Bui J, Ardakani M, Tan I, Crocker A, Khattak A, Wood A. Metastatic Cellular Blue Nevus: A Rare Case With Metastasis Beyond Regional Nodes. Am J Dermatopathol. 2017; 39(8):618-621. https://doi.org/10.1097/DAD.0000000000000834 PMid:28244937

English J, McCollough M, Grabski W. A pigmented scalp nodule: malignant blue nevus. Cutis. 1996; 58(1):40-2. PMid:8823547

Bortolani A, Barisoni D, Scomazzoni G. Benign "metastatic" cellular blue nevus. Ann Plast Surg. 1994; 33(4):426-31. https://doi.org/10.1097/00000637-199410000-00013 PMid:7810962

Begum M, Lomme M, Quddus M. Nodal combined blue nevus and benign nevus cells in multiple axillary sentinel nodes in a patient with breast carcinoma: report of a case. Int J Surg Pathol. 2014; 22(6):570-3. https://doi.org/10.1177/1066896913509008 PMid:24220996

Zyrek-Betts J, Micale M, Lineen A, Bansal R, Bhaduri A, Pancholi Y, Balar D. Cellular blue nevus with nevus cells in regional lymph nodes: a lesion that mimics melanoma. Indian J Cancer. 1989; 26(3):145-50.

Chaudhuri P, Keil S, Xue J, Thomas J. Malignant blue nevus with lymph node metastases. J Cutan Pathol. 2008; 35(7):651-7. https://doi.org/10.1111/j.1600-0560.2007.00878.x PMid:17976211

Yan L, Tognetti L, Nami N, Lamberti A, Miracco C, Sun L, Fimiani M, Rubegni P. Melanoma arising from a plaque-type blue naevus with subcutaneous cellular nodules of the scalp. Clin Exp Dermatol. 2018; 43(2):164-167. https://doi.org/10.1111/ced.13287 PMid:29034495

Epstein J, Erlandson R, Rosen P. Nodal blue nevi. A study of three cases. The American Journal of Surgical Pathology. 1984; 8(12):907-915. https://doi.org/10.1097/00000478-198412000-00003 PMid:6097130

Sterchi M, Muss B, Weidner N. Cellular blue nevus simulating metastatic melanoma: report of an unusually large lesion associated with nevus-cell aggregates in regional lymph nodes. J Surg Oncol. 1987; 36(1):71-5. https://doi.org/10.1002/jso.2930360117 PMid:3626565

Davis J, Patil J, Aydin N, Mishra A, Misra S. Capsular nevus versus metastatic malignant melanoma – a diagnostic dilemma. Int J Surg Case Rep. 2016; 29: 20–24. https://doi.org/10.1016/j.ijscr.2016.10.040 PMid:27810606 PMCid:PMC5094157

Hocevar M, Kitanovski L, Frković S. Malignant blue nevus with lymph node metastases in five-year-old girl. Croat Med J. 2005; 46(3):463-6. PMid:15861528

Moreno-Ramírez D, Boada A, Ferrándiz L, Samaniego E, Carretero G, Nagore E, Redondo P, Ortiz-Romero P, Malvehy J, Botella-Estrada R; miembros del Grupo Espa-ol de Dermato-Oncología y Cirugía. Academia Espa-ola de Dermatología y Venereología. Lymph Node Dissection in Patients With Melanoma and Sentinel Lymph Node Metastasis: An Updated, Evidence-Based Decision Algorithm. Actas Dermosifiliogr. 2018. pii: S0001-7310(18)30083-8.

Delgado AF, Delgado AF. Complete lymph node dissection in melanoma: A systematic review and meta-analysis. Anticancer Res. 2017; 37(12):6825-6829. PMid:29187461

Gündüz K, Shields A, Shields L, Eagle C. Periorbital cellular blue nevus leading to orbitopalpebral and intracranial melanoma. Ophthalmology. 1998; 105(11):2046-50. https://doi.org/10.1016/S0161-6420(98)91122-8

Tchernev G, Voicu C, Mihai M, Lupu M, Tebeica T, Koleva N, Wollina U, Lotti T, Mangarov H, Bakardzhiev I, Lotti J, Franca K, Batashki A, Patterson W. Basal cell carcinoma surgery: simple undermining approach in two patients with different tumour locations. Open Access Maced J Med Sci. 2017; 5(4): 506–510. https://doi.org/10.3889/oamjms.2017.143 PMid:28785345 PMCid:PMC5535670

Published

2018-05-15

How to Cite

1.
Temelkova I, Stavrov K, Yungareva I, Wollina U, Mangarov H, Radinoff A, Popova TN, Tchernev G. Nevus Blue as a Sporadic Finding in a Patient with a Blue Toe?. Open Access Maced J Med Sci [Internet]. 2018 May 15 [cited 2024 Apr. 18];6(5):855-8. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.228

Issue

Section

C- Case Reports

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