Three Dimensional (3D) Echocardiography as a Tool of Left Ventricular Assessment in Children with Dilated Cardiomyopathy: Comparison to Cardiac MRI

Nevin Mohamed Habeeb; Omneya Ibrahim Youssef; Waleed Mohamed Elguindy; Ahmed samir Ibrahim; Walaa Hamed Hussein

doi:10.3889/oamjms.2018.270

Authors

Nevin Mohamed Habeeb Pediatrics Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Omneya Ibrahim Youssef Pediatrics Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Waleed Mohamed Elguindy Radiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Ahmed samir Ibrahim Pediatrics Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Walaa Hamed Hussein Pediatrics Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

DOI:

https://doi.org/10.3889/oamjms.2018.270

Keywords:

(3D) echocardiography, CMRI, DCM

Abstract

BACKGROUND: Left ventricular (LV) volumes and ejection fraction (EF) is Strong prognostic indicators for DCM. Cardiac MRI (CMRI) is a preferred technique for LV volumes and EF assessment due to high spatial resolution and complete volumetric datasets. Three-dimensional echocardiography is a promising new technique under investigations.

AIM: Evaluate 3D echocardiography as a tool in LV assessment in DCM children about CMRI.

PATIENTS AND METHODS: A group of 20 DCM children (LVdiastolic diameter < 2 Z score, LVEF < 35%) at Children s Hospital, Ain-Shams University (gp1) (mean age 6.6 years) were compared to 20 age and sex-matched children as controls (gp2). Patients were subjected to: clinical examination, conventional echocardiography, automated 3D LV quantification, 3D speckle tracking echocardiography (3D-STE) (VIVID E9 Vingmed, Norway) and CMRI (Philips Achieva Nova, 1.5 Tesla scanner) for LV end systolic volume (LVESV), LVend diastolic volume (LVEDV) that were indexed to body surface area, EF% and wall motion abnormalities assessment.

RESUTS: No statistically significant difference was found between automated 3D LV quantification echocardiography, 3D-STE, and CMRI in ESV/BSA and EDV/BSA assessment (p = 1, 0.99 respectively), between automated LV quantification echocardiography and CMRI in EF% assessment (p = 0.99) and between CMRI and 3D-STE in LV Global hypokinesia detection (P = 0.255). As for segmental hypokinesia CMRI was more sensitive [45% of patients vs. 40%, (P = 0,036), basal septal hypokinesia 85% vs. 75%, (p = 0.045), mid septal hypokinesia 80% vs. 65%, (p = 0.012) and lateral wall hypokinesia 75% vs. 65%, (p = 0.028)].

CONCLUSION: Automated 3D LV quantification echocardiography and 3D-STE are reliable tools in LV volumetric and systolic function assessment about CMRIas a standard method. 3D speckle echocardiography is comparable to CMRI in global wall hypokinesia detection but less sensitive in segmental wall hypokinesia which mandates further studies.

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