Behçet's Disease – Case Presentation and Review Literature

Authors

  • Mergita Ferizi Family Medical Center of Prishtina, Prishtina
  • Antigona Gerqari University Clinical Center of Kosovo, Clinic of Dermatology, Prishtina, Kosovo
  • Mybera Ferizi Family Medical Center of Prishtina, Prishtina, Kosovo

DOI:

https://doi.org/10.3889/oamjms.2018.393

Keywords:

Aft syndrome, Behçet's syndrome, Mucosal ulceration, HLA-B51

Abstract

BACKGROUND: Behçet's syndrome is associated with inflammation of various areas of the body. Sy. Behcet is a rare, chronic, recurrent disease characterised by changes in the: Arteries that supply blood to the body's tissues, veins that take the blood back to the lungs, the back of the eye's retina, brain, joints, skin and bowels. There is a close correlation between the geographical distribution of HLA-B51 and its prevalence. In the etiopathogenesis, there are indications of genetic susceptibility associated with environmental influence. Although aetiology is not yet known, it is thought of viral or autoimmune genes but is not yet confirmed by relevant analysis.

CASE REPORT: This was a case of a 29 years old young female presenting with recurrent oral and genital ulcers. Eye lesions usually start in one eye and then pass to the other eye. They are like iridocyclitis extending very quickly to another eye. Three months later, a few shifts were introduced in the form of small initial ulcers, which for 4-5 days have been enlarged and then epithelized by leaving the catapult in the genital mucus. In the skin of the lower extremities, papules appear to be as large as corn grain.

CONCLUSION: Diagnosis of Behçet's syndrome is determined based on eye changes, oral mucous and genital mucosa. Treatment of Behçet's syndrome depends on the severity and the location of its manifestations.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Scherrer MAR, Rocha VB, Garcia LC. Behçet's disease: review with emphasis on dermatological aspects. Anais Brasileiros de Dermatologia. 2017; 92(4):452-464. https://doi.org/10.1590/abd1806-4841.20177359 PMid:28954091 PMCid:PMC5595589

Diseases of the skin. Andrews London, 1982:999-1000.

Jakac D. Dermatologija i Venerologija. Medicinska knjiga Beograd-Zagreb, 1981; 396-397

Behcet H. Uber rezidivierende, aphthose, durchein Virus verursachte Geschwure am Mund, am Auge und anden Genitalien. Dermatol Wochenschr. 1937; 36:1152-7.

Boe J, Dalgaard JB, Scott D. Mucocutaneous-ocular syndrome with intestinal involvement; a clinical and pathological study of four fatal cases. Am J Med. Dec. 1958; 25(6):857-67. https://doi.org/10.1016/0002-9343(58)90058-5

Kim DK, Chang SN, Bang D, Lee ES, Lee S. Clinical analysis of 40 cases of childhood-onset Behcet's disease. Pediatr Dermatol. 1994; 11(2):95-101. https://doi.org/10.1111/j.1525-1470.1994.tb00559.x PMid:8041669

Mizushima Y. [Revised diagnostic criteria for Behcet's disease in 1987]. Ryumachi. 1988; 28(1):66-70. PMid:3388149

International Study Group for Behcet's Disease. Criteria for diagnosis of Behcet's disease. Lancet. 1990; 335(8697):1078-80. PMid:1970380

Tugal-Tutkun I, Urgancioglu M. Childhood-onset uveitis in Behcet disease:a descriptive study of 36 cases. Am J Ophthalmol. 2003; 136(6):1114-9. https://doi.org/10.1016/S0002-9394(03)00791-8

Best Evidence] Saadoun D, Wechsler B, Resche-Rigon M, et al. Cerebral venous thrombosis in Behcet's disease. Arthritis Rheum. 2009; 61(4):518-26. https://doi.org/10.1002/art.24393 PMid:19333987

Hatemi G, Seyahi E, Fresko I, Talarico R, Hamuryudan V. Clin Exp Rheumatol. 2015; 33(6 Suppl 94):S3-14. PMid:26487500

Bang D, Lee ES, Sohn S. Behçet's Disease: A Guide to its Clinical Understanding Textbook and Atlas. Springer Science & Business Media, 2001.

Alpsoy E, Zouboulis CC, Ehrlich GE. Yonsei Med J. 2007; 48(4):573-85. https://doi.org/10.3349/ymj.2007.48.4.573 PMid:17722228 PMCid:PMC2628050

Lee S, Bang D, Lee E, Sohn S. Behçet's Disease: a guide to its clinical understanding. New York: Springer-Velag, 2001. https://doi.org/10.1007/978-3-642-56455-0

Saleh Z, Arayssi T. Ther Adv Chronic Dis. 2014; 5(3):112-34. https://doi.org/10.1177/2040622314523062 PMid:24790727 PMCid:PMC3992825

Hatemi G, Silman A, Bang D, Bodaghi B, Chamberlain AM, Gul A, Houman MH, Kötter I, Olivieri I, Salvarani C, Sfikakis PP, Siva A, Stanford MR, Stübiger N, Yurdakul S, Yazici H, EULAR Expert Committee. Ann Rheum Dis. 2008; 67(12):1656-62. https://doi.org/10.1136/ard.2007.080432 PMid:18245110

Hatemi G, Silman A, Bang D, Bodaghi B, Chamberlain AM, Gul A, Houman MH, Kötter I, Olivieri I, Salvarani C, Sfikakis PP, Siva A, Stanford MR, Stübiger N, Yurdakul S, Yazici H. Ann Rheum Dis. 2009; 68(10):1528-34. https://doi.org/10.1136/ard.2008.087957 PMid:18420940

Published

2018-10-03

How to Cite

1.
Ferizi M, Gerqari A, Ferizi M. Behçet’s Disease – Case Presentation and Review Literature. Open Access Maced J Med Sci [Internet]. 2018 Oct. 3 [cited 2021 Apr. 12];6(10):1871-4. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.393

Issue

Section

C- Case Reports

Most read articles by the same author(s)