Vaspin in Developing Obesity (Vande-Ob); the Correlation of Waist Circumference and Visceral Fat Percentage with Vaspin Levels in Patients with Type II Diabetes Mellitus

I Made Pande Dwipayana; I Made Siswadi Semadi; Wira Gotera; Made Ratna Saraswati; Ketut Suastika

doi:10.3889/oamjms.2019.011

Authors

I Made Pande Dwipayana Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia; Doctoral Program, Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia http://orcid.org/0000-0002-1825-0097
I Made Siswadi Semadi Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia http://orcid.org/0000-0003-4298-6544
Wira Gotera Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia http://orcid.org/0000-0002-1601-5077
Made Ratna Saraswati Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia http://orcid.org/0000-0003-3116-6575
Ketut Suastika Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2019.011

Keywords:

vaspin, waist circumference, visceral fat percentage, type II diabetes mellitus

Abstract

BACKGROUND: Vaspin concentration was thought to be associated with obesity, impaired insulin sensitivity, and fitness level. The correlation of vaspin and leptin supports the theory of vaspin associated with body fat mass.

AIM: To determine the correlation between visceral fat distributions and serum vaspin level in type II DM patients.

METHODS: We conduct an observational, analytical cross-sectional study. Sixty subjects with type II diabetes mellitus who came to Diabetes Center of Sanglah General Hospital were included consecutively. Each subject has to sign an informed consent before physical and laboratory examination took place. Spearman correlation test was used to analyse the correlation between waist circumference and visceral fat percentage with serum vaspin level since the data were not distributed normally.

RESULTS: Mean laboratory results in all subjects of vaspin levels was 2.389 Â± 3.586 ng/ml, mean waist circumference was 94.95 Â± 11.78 cm and mean visceral fat percentage was 18.05 Â± 23.63%. We found we found no significant correlation between between vaspin with waist circumference (r = -0.044; p = 0.738) and visceral fat percentage (r = -0.103; p = 0.435).

CONCLUSIONS: The vaspin level did not significantly correlate with waist circumference and visceral fat percentage in type II diabetes patients.

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