In Vitro Antibiotic Resistance in Bacterial Infected Eczema at Ho Chi Minh City Hospital of Dermatology

Diep Le Ngoc; Ly Nguyen Thi Vu; Tro Chau Van; Vinh Ngo Minh; Hao Nguyen Trong; Thuong Nguyen Van; Khang Tran Hau; Marco Gandolfi; Francesca Satolli; Claudio Feliciani; Michael Tirant; Aleksandra Vojvodic; Na Pham Thi Bich; Torello Lotti

doi:10.3889/oamjms.2019.067

Authors

Diep Le Ngoc Medical University of Ho Chi Minh City, Ho Chi Minh City, Vietnam
Ly Nguyen Thi Vu Medical University of Ho Chi Minh City, Ho Chi Minh City, Vietnam
Tro Chau Van Department of Dermatology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam
Vinh Ngo Minh Department of Dermatology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam
Hao Nguyen Trong HCMC Hospital of Dermato-Venereology, Ho Chi Minh City, Vietnam
Thuong Nguyen Van National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Khang Tran Hau National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Marco Gandolfi Unit of Dermatology, University of Parma, Parma, Italy
Francesca Satolli Unit of Dermatology, University of Parma, Parma, Italy
Claudio Feliciani Unit of Dermatology, University of Parma, Parma, Italy
Michael Tirant University of Rome G. Marconi, Rome, Italy; Psoriasis Eczema Clinic, Melbourne, Australia
Aleksandra Vojvodic Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia
Na Pham Thi Bich Medical University of Ho Chi Minh City, Ho Chi Minh City, Vietnam
Torello Lotti University of Rome G. Marconi, Rome, Italy

DOI:

https://doi.org/10.3889/oamjms.2019.067

Keywords:

Infected eczema, Antibiotics resistance

Abstract

BACKGROUND: Infected eczema is one of the most common complications of eczema. The progression and treatment of infected eczema have become more complex and difficulty due to the antibiotic resistance of bacteria and the abuse of antibiotics in treatment.

AIM: Our research was conducted with the aim of investigating the severity of in vitro antibiotic resistance in patients with bacterially infected eczema at Ho Chi Minh City Hospital of Dermatology.

METHODS: We studied 40 cases of patients, suffering from atopic dermatitis, contact dermatitis, vesicular palmoplantar eczema, with positive results of infected eczema.

RESULTS: S. aureus accounted for 82.5%, followed by S. epidermidis (15%), P. aeruginosa (12.5%), S. pyogenes (5%) accounted for a small percentage. E. coli (2.5%) and M. morganii (2.5%) accounted for the lowest percentage. Both MSSA and MRSA were completely resistant to penicillin. MRSA is completely resistant to penicillin, erythromycin, and cefuroxime, highly resistant to clindamycin (82.35%). Our research showed that Pseudomonas aeruginosa was not resistant to a variety of antibiotics. It was completely resistant to tetracycline, trimethoprim/sulfamethoxazole (100%). Most bacteria are highly sensitive to linezolid, vancomycin as other studies in the world shown. There are also rifampicins, pristinamycin. Hence, it`s prioritised to be used for only patients with eczema infected with multidrug-resistant bacteria.

CONCLUSION: Penicillin is not recommended for the treatment for infected eczema. Linezolid, vancomycin has a high sensitivity to bacteria including multidrug-resistant bacteria like MRSA.