Atypical Manifestations in Classic Kaposi Sarcoma: Case Series of Two Patients HIV - Negative

Tiziana Peduto; Francesco Cillo; Paola Nappa; Mario Delfino; Gabriella Fabbrocini; Maria Ferrillo

doi:10.3889/oamjms.2019.162

Authors

Tiziana Peduto Department of Dermatology, University of Naples Federico II, Via Pansini, 5 80131 Napoli, Italy
Francesco Cillo Department of Dermatology, University of Naples Federico II, Via Pansini, 5 80131 Napoli, Italy
Paola Nappa Department of Dermatology, University of Naples Federico II, Via Pansini, 5 80131 Napoli, Italy
Mario Delfino Department of Dermatology, University of Naples Federico II, Via Pansini, 5 80131 Napoli, Italy
Gabriella Fabbrocini Department of Dermatology, University of Naples Federico II, Via Pansini, 5 80131 Napoli, Italy
Maria Ferrillo Department of Dermatology, University of Naples Federico II, Via Pansini, 5 80131 Napoli, Italy

DOI:

https://doi.org/10.3889/oamjms.2019.162

Keywords:

eye, classic kaposi sarcoma, chemotherapy, vinblastine

Abstract

BACKGROUND: Kaposi's sarcoma (KS) is a tumour of endothelial, blood and lymphatic cells, caused by an infection with human herpesvirus-8 (HHV-8). The skin lesions of KS, especially of the classical or Mediterranean variant (CKS), are represented by red-purple macules, plaques and nodules, localised mainly on the extremities.

CASE REPORT: This case series intend to describe multifocal atypical kaposian manifestations in two HIV negative subjects, affected by CKS, treated with successful chemotherapy.

CONCLUSIONS: Although atypical manifestations are extremely rare events, we suggest an accurate, objective examination because a prompt diagnosis can lead to a vital intervention in the patient's health and sometimes to the identification of the disease itself.

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