Management Comprehensive Multidisciplinary of Malignant Ovarian Germ Cell Tumors and Feto - Maternal Outcome: A Case Series Report and Literature Review

Authors

  • Lany Christina Prajawati Ni Luh Obstetrics and Gynaecologic Registrar, Obstetrics and Gynecologic Department, Bali, Indonesia
  • I Nyoman Bayu Mahendra Oncology-Gynecology Division, Bali, Indonesia
  • Ketut Suwiyoga Oncology-Gynecology Division, Bali, Indonesia
  • ING Budiana Oncology-Gynecology Division, Bali, Indonesia
  • IGP Mayun Mayura Oncology-Gynecology Division, Bali, Indonesia
  • AAG Putra Wiradnyana Maternal-Fetal Medicine Division, Bali, Indonesia
  • I Wayan Artana Putra Maternal-Fetal Medicine Division, Bali, Indonesia
  • I Ketut Surya Negara Maternal-Fetal Medicine Division, Bali, Indonesia
  • Ketut Ariawati Hematology-Oncology Pediatric Division, Bali, Indonesia
  • IGA Sri Mahendra Dewi Pathology Department, Sanglah General Hospital, Udayana University, Bali, Indonesia
  • AAA Ngurah Susraini Pathology Department, Sanglah General Hospital, Udayana University, Bali, Indonesia
  • Ni Putu Sriwidyani Pathology Department, Sanglah General Hospital, Udayana University, Bali, Indonesia
  • Wahyudi Wirawan Obstetrics and Gynaecologic Registrar, Obstetrics and Gynecologic Department, Bali, Indonesia
  • Ida Ayu Vikananda Obstetrics and Gynaecologic Registrar, Obstetrics and Gynecologic Department, Bali, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2019.251

Keywords:

Ovarian malignant germ cell tumours, Pregnancy, Chemotherapy, Surgical staging

Abstract

BACKGROUND: Malignant Ovarian Germ Cell Tumors (MOGCT) most commonly occur in young women in the reproductive age group. Timely antenatal diagnosis and treatment of the tumour to enhance maternal and perinatal outcomes are the main challenges confronting the obstetrician and the gyne-oncologist.

CASE PRESENTATION: Here we present three cases of pregnancy complicated with MOGCTs. The first case (immature teratoma) was complicated by maternal psychological symptoms consistent with stress and histopathological examination confirmed the diagnosis of premature ovarian failure (POF). The second case (dysgerminoma) preterm labour occurred as an obstetric complication, but the baby was born in good condition without IUGR. The third case (yolk sac tumour) treated with docetaxel (brexel)-carboplatin chemotherapy administration there was no maternal or fetal complication. At the end of the pregnancy and delivery, complete surgical staging and cytoreduction were performed, and no metastases were found.

CONCLUSION: Optimal management strategies centre on a multi-disciplinary comprehensive team approach is critical resulting in better outcomes for the mother and the baby by avoiding complications.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

Downloads

Published

2019-04-03

How to Cite

1.
Ni Luh LCP, Mahendra INB, Suwiyoga K, Budiana I, Mayura IM, Wiradnyana AP, Putra IWA, Negara IKS, Ariawati K, Dewi ISM, Susraini AN, Sriwidyani NP, Wirawan W, Vikananda IA. Management Comprehensive Multidisciplinary of Malignant Ovarian Germ Cell Tumors and Feto - Maternal Outcome: A Case Series Report and Literature Review. Open Access Maced J Med Sci [Internet]. 2019 Apr. 3 [cited 2024 Apr. 24];7(7):1174-9. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2019.251

Issue

Vol. 7 No. 7 (2019): Apr 15 (OAMJMS)

Section

C- Case Reports

License

Copyright (c) 2019 Lany Christina Prajawati Ni Luh, I Nyoman Bayu Mahendra, Ketut Suwiyoga, ING Budiana, IGP Mayun Mayura, AAG Putra Wiradnyana, I Wayan Artana Putra, I Ketut Surya Negara, Ketut Ariawati, IGA Sri Mahendra Dewi, AAA Ngurah Susraini, Ni Putu Sriwidyani, Wahyudi Wirawan, Ida Ayu Vikananda

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

http://creativecommons.org/licenses/by-nc/4.0

Crossref
Scopus
Google Scholar
Europe PMC

Most read articles by the same author(s)