Assessing the Status of Filtering Blebs at 5 Year Post- Trabeculectomy

Bui Thi Van  Anh; Nguyen Thai  Dat; Anh Tuan  Vu; Nguyen Trung  Hieu; Do  Quyet; Than Van  Thai; Vu Thi  Nga; Toi  Chu Dinh; Nguyen Duy Bac

doi:10.3889/oamjms.2019.374

Authors

Bui Thi Van Anh Vietnam National Institute of Ophthalmology, Hanoi, Vietnam
Nguyen Thai Dat Vietnam National Institute of Ophthalmology, Hanoi, Vietnam
Anh Tuan Vu Hanoi Medical College, Hanoi, Vietnam
Nguyen Trung Hieu Ninhbinh Province Eye Hospital, Ninh Binh, Vietnam
Do Quyet Vietnam Military Medical University (VMMU), Hanoi, Vietnam
Than Van Thai NTT Hi-tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam
Vu Thi Nga Institute for Research and Development, Duy Tan University, 03 Quang Trung, Danang, Vietnam
Toi Chu Dinh Department of Human and Animal Physiology, Faculty of Biology, Hanoi National University of Education, Hanoi, Vietnam
Nguyen Duy Bac 1

DOI:

https://doi.org/10.3889/oamjms.2019.374

Keywords:

Filtering bleb, OCT anterior, Trabeculectomy

Abstract

BACKGROUND: Glaucoma is a common cause of blindness in the world as well as in Vietnam. It is treated by many different methods but trabeculectomy is still the most popular and highly effective surgical method to treat this condition.

AIM: To analyze the status of 5 years filtering blebs following trabeculectomy and to explore multiple factors associated with filtering blebs.

METHODS: This is a retrospective, cross-sectional descriptive study. Eyes had been performed trabeculectomy for 5 years were included in these results. The filtering blebs were assessed using slit lamp and OCT. the OCT captured bleb area to evaluate fluid subconjunctival spaces, thickness and height of bleb and to evaluate the related factors

RESULTS: A group of 106 primary glaucoma eyes of 97 patients (88 patients with 1 eye, 9 patients 2 eyes) had been performed trabeculectomy for 5 years were taken OCT anterior image. The proportion of female patients is 1.5 times that of male patients. IOP was controlled with or without topical medication in all eyes. The filtering bleb had a high echo reflection, which accounted for 42.5%, the average echo reflection was 38.6%, the low echo reflection response of 18.9%. 66% of the eyes had the aqueous space under the conjunctiva, 65.1% have the aqueous space under sclera flap, the average height of the bleb on OCT was 0.4 mm Â± 0.3 mm. Young patients often have a higher rate of bleb fibrosis and loss of function than older patients

CONCLUSION: OCT is capable of assessing the function of bleb. After 5 years of trabeculectomy, on the OCT image, most cases of blebs are maintaining drainage function.