Co-Infection of Human Papillomavirus with Mycoplasma Hominis/Ureaplasma Urealyticum Among Female Sex Workers in Medan, Indonesia

Abstract

Human papillomavirus (HPV) infection is one of the most prevalent sexually transmitted diseases among women aged < 35 years worldwide. Recent studies have suggested that the vaginal microenvironment influenced by bacterial infection poses for high-risk human papillomavirus (hrHPV) infection and cervical carcinogenesis. Female sex workers (FSWs) are a population susceptible to acquire Human Immunodeficiency Virus (HIV) and sexually transmitted infections (STIs), as well as transmitting the virus to others. The aim of this study is to evaluate the relationship between Mycoplasma/Ureaplasma infections and HPV infection among female sex workers. A total of 70 female sex workers of reproductive age were recruited from various location in Medan, Indonesia in 2018. Detection of Mycoplasma/Ureaplasma infections and HPV infection were obtained from PCR assessment. The results of this study showed that no correlation significant between Mycoplasma hominis/Ureaplasma urealyticum infection and HPV infection.