Evaluation of Pregnancy Outcomes at Advanced Maternal Age

Authors

  • MaÅ‚gorzata RadoÅ„-Pokracka Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Kraków, Poland
  • Beata Adrianowicz Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Kraków, Poland
  • Magdalena PÅ‚onka Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Kraków, Poland
  • Paulina DaniÅ‚ Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Kraków, Poland
  • Magdalena Nowak Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Kraków, Poland
  • Hubert Huras Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Kraków, Poland

DOI:

https://doi.org/10.3889/oamjms.2019.587

Keywords:

advanced maternal age, pregnancy outcomes, perinatology, pregnancy complications

Abstract

AIM: The study aimed to investigate the association between advanced maternal age (AMA) and the risk of adverse maternal, perinatal and neonatal outcomes about parity in singleton pregnancies.
METHODS: We retrospectively analysed 950 women who gave birth in the Department of Obstetrics and Perinatology of the University Hospital in Kraków for six months (between 1st January and 30th June 2018). The patients were divided into 3 groups according to their age (30-34 years old, 35-39 years old and over 40 years old). Each of these groups was subsequently subdivided into 2 groups depending on parity (primiparae and multiparae). Maternal, perinatal and neonatal outcomes were compared between the groups and the subgroups.
RESULTS: Comparison of the three age groups revealed that advanced maternal age might constitute a predisposing factor for preterm birth, caesarean section and large for gestational age (LGA). From these parameters, statistical significance was reached in case of greater risk of LGA (OR = 2.17), caesarean section (OR = 2.03) and elective C-section (OR = 1.84) in women over 40 years old when compared to the patients aged 30-34. Furthermore, AMA increases the risk of postpartum haemorrhage (OR = 6.43). Additionally, there is a negative correlation between maternal age and gestational age at delivery (R = -0.106, p < 0.05).
CONCLUSIONS: Advanced maternal age can undoubtedly be associated with several adverse perinatal outcomes. At the same time, the risk of perinatal complications begins to increase after the age of 35 but becomes significant in women aged ≥ 40.

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Published

2019-07-01

How to Cite

1.
Radoń-Pokracka M, Adrianowicz B, Płonka M, Danił P, Nowak M, Huras H. Evaluation of Pregnancy Outcomes at Advanced Maternal Age. Open Access Maced J Med Sci [Internet]. 2019 Jul. 1 [cited 2022 Dec. 9];7(12):1951-6. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2019.587

Issue

Section

B - Clinical Sciences