Immunocompromised Districts of Skin: A Case Series and a Literature Review

Aleksandra Vojvodic; Michael Tirant; Veronica di Nardo; Torello Lotti; Uwe Wollina

doi:10.3889/oamjms.2019.680

Authors

Aleksandra Vojvodic Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia
Michael Tirant Department of Dermatology, University of Rome â€œG. Marconiâ€, Rome, Italy; Hanoi Medical University, Hanoi, Vietnam
Veronica di Nardo Department of Dermatology, University of Rome â€œG. Marconiâ€, Rome, Italy
Torello Lotti Department of Dermatology, University of Rome â€œG. Marconiâ€, Rome, Italy
Uwe Wollina Department of Dermatology and Allergology, StÃ¤dtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany

DOI:

https://doi.org/10.3889/oamjms.2019.680

Keywords:

Koebner phenomenon; Wolf's isotopic response, Immunocompromised districts of skin

Abstract

BACKGROUND: The concept of immunocompromised districts of skin has been developed by Ruocco and helps to explain certain aspects of the macromorphology of skin diseases. This concept unites the isomorphic response of Koebner and the isotopic response of Wolf.

CASE REPORTS: We present different cutaneous conditions which can lead to immunocompromised districts of skin such as scars, radiodermatitis, lymphedema, disturbed innervation or mechanical friction etc. Typical and rarer skin disorders associated with them are discussed and illustrated by their observations.

CONCLUSION: At this moment, we wish to inform dermatologists and non-dermatologists about Ruoccoâ€™s concept and its implications.