Erythema Elevatum Diutinum - Two Case Reports, Two Different Clinical Presentations, and a Short Literature Review
Keywords:Leukocytoclastic vasculitis, Infections, Autoimmune disorders, Hematologic disorders, Dapsone, Erythema elevatum diutinum
BACKGROUND: Erythema elevatum diutinum (EED) belongs to the spectrum of cutaneous leukocytoclastic vasculitides. EED is a very rare dermatosis presenting with reddish to browning papules and plaques. EED may be associated with infections, hematologic and autoimmune disorders.
CASE REPORTS: We present two patients with EED, a 50-year-old woman and a 42-year-old man. While the woman shows an association with colitis ulcerosa, the man had an anti-thrombin deficiency. Treatment was started with oral corticosteroid and dapsone, respectively. In both cases, there was a partial and temporary response.
CONCLUSIONS: EED is a rare vasculitis with an unusual clinical presentation and a chronic course. Response to treatment is unsatisfactory and in the long-term run sometimes frustrating.
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Copyright (c) 2019 Uwe Wollina, Claudia KrÃ¶nert, AndrÃ© Koch, Jacqueline SchÃ¶nlebe, Aleksandra Vojvodic, Torello Lotti (Author)
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