@article{Poposka_Boskov_Risteski_Taleski_Janusevski_Srbinovska_Georgievska-Ismail_2018, title={Electrocardiographic Parameters as Predictors of Response to Cardiac Resynchronization Therapy}, volume={6}, url={https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.092}, DOI={10.3889/oamjms.2018.092}, abstractNote={<p><strong>INTRODUCTION:</strong> Although strict selection criteria are used to select patients for cardiac resynchronisation therapy, up to 30% of patients do not have a positive clinical response.</p><p><strong>PATIENTS:</strong> A total of 102 consecutive patients who had biventricular pacemaker/defibrillator (CRT-P or CRT-D) implanted were enrolled in this prospective observational study.</p><p><strong>RESULTS:</strong> During the average follow-up period of 24.3 months 5 patients died and 17 (16.7%) patients were hospitalised with the symptoms of heart failure; 75 (73.5%) patients were responders based on the previously defined criteria. Responders in the group of LBBB patients kept the significant difference in a computed variable (S1 + R6) - (S6 + R1) and R6/S6 ratio. Responders in non-LBBB patients kept the significant difference only in the height of R waves in V6. The R6/S6 ratio tended to be higher, but it did not reach a statistical significance.</p><p><strong>CONCLUSION:</strong> None of the tested ECG parameters stands out as an independent predictor of response to cardiac resynchronisation therapy, but some of them were different in responder-compared to the non-responder group. The amplitude of R wave in V6, higher R/S ratio in V6 and higher computed variable (S1 + R6) - (S6 + R1) may predict the likelihood of response to CRT therapy in both LBBB-patients and non-LBBB patients.<em></em></p>}, number={2}, journal={Open Access Macedonian Journal of Medical Sciences}, author={Poposka, Lidija and Boskov, Vladimir and Risteski, Dejan and Taleski, Jane and Janusevski, Filip and Srbinovska, Elizabeta and Georgievska-Ismail, Ljubica}, year={2018}, month={Feb.}, pages={297–302} }