@article{Tchernev_Yungareva_Mangarov_Stavrov_Lozev_Temelkova_Chernin_Pidakev_Tronnier_2018, title={Pretibial Located Stewart-Treves Syndrome: Uncommon Presentation in a Bulgarian Patient!}, volume={6}, url={https://oamjms.eu/index.php/mjms/article/view/oamjms.2018.191}, DOI={10.3889/oamjms.2018.191}, abstractNote={<p><strong>BACKGROUND: </strong>The Stewart-Treves syndrome with localisation in the region of the lower extremities is not something unusual as clinical pathology, but the clinical diagnostics is rather difficult, and it can be further complicated maximally because of: the similar locoregional findings in patients with other cutaneous malignancies.</p><p><strong>CASE REPORT: </strong>Presented is a rare form of an epithelioid variant of the Stewart Treves syndrome in a woman, aged 81, localised in the region of the lower leg and significantly advanced only for 2 months. The diagnosis was confirmed histologically and immunohistochemically. Amputation of the affected extremity was planned. Discussed are important etiopathogenetic aspects regarding the approach in patients with lymphedema and possibility for development of the Stewart Treves syndrome.</p><p><strong>CONCLUSION: </strong>Analyzing the evidence from the literature worldwide, we concluded that perhaps the only reliable (to some extent) therapeutic option in patients with Stewart Treves Syndrome is 1) the early diagnostics and 2) the following inevitable radical excision or amputation with the maximal field of surgical security in the proximal direction.</p>}, number={4}, journal={Open Access Macedonian Journal of Medical Sciences}, author={Tchernev, Georgi and Yungareva, Irina and Mangarov, Hristo and Stavrov, Konstantin and Lozev, Ilia and Temelkova, Ivanka and Chernin, Svetoslav and Pidakev, Ivan and Tronnier, Michael}, year={2018}, month={Apr.}, pages={663–665} }