@article{Petri_Vrenjo_Angjeli_Abazaj_Kika_Koraqi_Daka_2022, title={Prevalence of Catheter-related Bloodstream Infection and Distribution of Multidrug Resistance Microorganisms among the Hospitalized Patients}, volume={10}, url={https://oamjms.eu/index.php/mjms/article/view/7464}, DOI={10.3889/oamjms.2022.7464}, abstractNote={<div> <p class="Pa6"><strong><span lang="EN-US">BACKGROUND: </span></strong><span lang="EN-US">Central venous catheter (VC)-related bloodstream infection (CRBSI) is associated with high rates of morbidity and mortality in critically ill patients over the world.</span></p> </div> <div> <p class="Pa6"><strong><span lang="EN-US">AIM: </span></strong><span lang="EN-US">The aims study is to evaluate the prevalence of CRBSI and to identify some of the factors.</span></p> </div> <div> <p class="Pa6"><strong><span lang="EN-US">METHODS: </span></strong><span lang="EN-US">This was a retrospective, observational study carried out in the tertiary care hospital “Mother Theresa,” Tirana and American Hospital, Tirana, over a period of 3 years from January 2016 to December 2018. Data were collected retrospectively from various electronic sources shared by the hospitals and linked using patients’ unique medical record numbers. A total of 170 patients with indwelling VC were included in the study. The catheters were cultured using the standard procedure. Statistical analysis version SPSS-20 software was used for calculation of data.</span></p> </div> <div> <p class="Pa6"><strong><span lang="EN-US">RESULTS: </span></strong><span lang="EN-US">Overall 170 patients analyzed in this study, the prevalence of CRBSI results 58.8%. The positivity from the University Hospital Center (UHC) “Mother Theresa” resulted 65.1% (82/126 cases) and the positivity from American Hospitals (AH) resulted 40.91% (18/44 cases). Patients from UHC Mother Theresa were (odds ratio) 2.69 times higher in risk for CRBSI compared to patients from AH, for confidence interval 95% (1.33–5.44) p value resulted to be with strong association = 0.005. The average age resulted 59.68 ± 14.26, with minimum age 9 years old and maximum age 83 years old. The most infected age groups resulted patients with age 61–70 years old. Central VC had a higher positivity compared to other catheters types. Regarding the spectrum of bacteria implicated in CRBSI infections, Gram positive bacteria (67%) were the most predominant compared to Gram-negative bacteria (33%), but regarding the antimicrobial resistance, the Gram-negative bacteria resulted majority of multidrug resistance.</span></p> </div> <div><strong>CONCLUSION: </strong>The overall prevalence of CRBSI was 58.8%. Patients from Mother Theresa Hospital have the highest prevalence compared to patients of American Hospital. Men patients were the most predominant sex; age groups 61–70 years old presented the highest positive cases with CRBSI. <em>Staphylococcus </em>spp<em>., Acinetobacter </em>spp., <em>Proteus </em>spp., etc., were the most common isolate. We found antimicrobial resistance almost in all bacteria, but Gram-negative bacteria resulted majority of multidrug resistance.</div>}, number={A}, journal={Open Access Macedonian Journal of Medical Sciences}, author={Petri, Oltiana and Vrenjo, Klotilda and Angjeli, Alda and Abazaj, Erjona and Kika, Blerta and Koraqi, Andi and Daka, Albana}, year={2022}, month={Jan.}, pages={181–186} }