TY - JOUR AU - Alagha, Ebaa AU - Samy, Amira Mohammad PY - 2021/01/21 Y2 - 2024/03/29 TI - Effect of Different Remineralizing Agents on White Spot Lesions JF - Open Access Macedonian Journal of Medical Sciences JA - Open Access Maced J Med Sci VL - 9 IS - D SE - Prosthodontics DO - 10.3889/oamjms.2021.5662 UR - https://oamjms.eu/index.php/mjms/article/view/5662 SP - 14-18 AB - <p><strong>AIM: </strong>This study evaluated the impact of two remineralizing agents containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and tricalcium phosphate (TCP) on white spot lesions.</p><p><strong>MATERIALS AND METHODS: </strong>A total of 90 freshly extracted upper premolars were divided in three equal groups (30 each): Group A: Control group, Group B: Varnish containing CPP-ACP, and Group C: Varnish containing TCP. The teeth were subjected to Diagnodent test after inducing white spot lesions to assess any surface changes present on the teeth. The readings were repeated post-demineralization and post-remineralization.</p><p><strong>RESULTS: </strong>Statistically significant difference was present in the mean values between the tested groups. CPP-ACP group recorded higher mean value at demineralization when compared to TCP group. Statistically significant difference (p &lt; 0.00`01) was present between the baseline and the demineralization values. CPP-ACP group presented higher remineralization results when compared to TCP group. T-test proved a significant difference between the tested groups.</p><p><strong>CONCLUSION: </strong>CPP-ACP containing varnish had higher remineralizing effect when compared to TCP containing varnish.</p><p><strong>CLINICAL SIGNIFICANCE: </strong>Recently, the focus of restorative dentistry has been directed toward a conservative approach. Prevention and non-restorative treatment of initial enamel caries is the main concern. Remineralization procedures are the most preferred way of regeneration of lost tooth structure.</p> ER -