TY - JOUR AU - Purnamantara, I Made Dwi AU - Wiargitha, I Ketut AU - Mahadewa, Tjok Gede Bagus PY - 2021/10/06 Y2 - 2024/03/29 TI - Role of Neutrophil-to-Lymphocyte Ratio as a Predictor of Systemic Inflammatory Response Syndrome in Blunt Abdominal Trauma Following Emergency Laparotomy in Sanglah General Hospital, Denpasar JF - Open Access Macedonian Journal of Medical Sciences JA - Open Access Maced J Med Sci VL - 9 IS - B SE - Surgery DO - 10.3889/oamjms.2021.6699 UR - https://oamjms.eu/index.php/mjms/article/view/6699 SP - 1105-1110 AB - <div><p class="Pa6"><strong><span lang="EN-US">BACKGROUND: </span></strong><span lang="EN-US">Abdominal trauma, both blunt and penetrating abdominal trauma, is the third most common trauma, which is about 10% after head trauma (30%) and chest trauma (20%). Trauma has an influence on the balance of the immune system. The excessive inflammatory response can trigger systemic inflammatory response syndrome (SIRS). The ratio of neutrophils to lymphocytes acts as a marker of the inflammatory response in both surgical and non-surgical patients.</span></p></div><div><p class="Pa6"><strong><span lang="EN-US">AIM: </span></strong><span lang="EN-US">The purpose of the study was to predict the incidence of SIRS using neutrophils-to-lymphocytes ratio (NLR) in patients with blunt abdominal trauma undergoing emergency laparotomy.</span></p></div><div><p class="Pa6"><strong><span lang="EN-US">METHODS: </span></strong><span lang="EN-US">This study is an observational analytic study with a prospective design which was carried out at the emergency room, intensive care unit, Sanglah Hospital, Denpasar, Surgery for 1 year from January 2019 to December 2019, involving 59 research subjects with the consecutive sampling method who is met the inclusion and exclusion criteria.</span></p></div><div><p class="Pa6"><strong><span lang="EN-US">RESULTS: </span></strong><span lang="EN-US">The area under the curve value obtained an NLR sensitivity of 87.1% with a cutoff point of 5.25. In the path analysis, it was found that NLR was the dominant factor and had a positive effect of 43.9% (p </span><span lang="EN-US">&lt; 0.001</span><span lang="EN-US">) on SIRS.</span></p></div><div><strong>CONCLUSION: </strong>NLR is expected to be used as a reference to predict the incidence of SIRS in blunt abdominal trauma following laparotomy emergency.</div> ER -