Consequences of Sleep Deprivation in Adult Diabetes Mellitus Type 2 Patients: An Integrative Review

Authors

  • Namkhang Polkern Woods Master Student of Nursing Science (International Program), Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand
  • Juraporn Tangpukdee Department of Pediatric Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand
  • Thiwawan Thepa Department of Midwife, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand
  • Nonglak Methakanchanasak Department of Adult Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand

DOI:

https://doi.org/10.3889/oamjms.2023.10029

Keywords:

DM type 2, Insomnia, Adult, Effect, Consequence, DM, Sleep disturbance, Sleep deprivation

Abstract

BACKGROUND: Sleep deprivation in individuals with diabetes mellitus type 2 is more prevalent than in ordinary people. At present, the adverse effects of diabetes type 2 people with sleep disorders and sleep deprivation on blood sugar control are irrefutable. Thorough assessments covering the whole structure should be of concern in health-care treatment. It is precipitated and delivered to the physical, mental health, and social environment, but no systematic review or minimal data were published. Furthermore, it may significantly affect the system more than existing research.

AIM: An integrative review aims to clarify the results or consequences of sleep disturbance/deprivation or insomnia symptoms among diabetes mellitus type 2 patients.

METHODS: The writers implemented a literature search in PubMed, CINAHL, and Medline using the terms DM type 2, insomnia, adult, effect, DM, sleep disturbance, sleep disorder, and a consequence between 2012 and 2022. Inclusion criteria selected through considering the entire article, and providing an abstract, were 20 articles.

RESULTS: Integrative data extraction and information were analyzed thematically. Identified were nine ideas: Association with blood sugar control, blood pressure control, risk of CVD, diabetes self-care behavior, weight gained and Obstructive Sleep Apnea (OSA), lifestyle and physical activity, mood/depression and anxiety symptoms, daily calories distribution, cholesterol/triglyceride, and liver enzyme levels.

CONCLUSION: The adverse effects of sleep deprivation in type 2 diabetes significantly affect all pathophysiologically, mentally, and lifestyle modifications, including diabetes self-care. Therefore, to highlight the importance of promoting optimum sleep in diabetes type2 patients, a health-care system is inevitably as necessary as diet and exercise management.

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References

Alshehri MM, Alothman SA, Alenazi AM, Rucker JL, Phadnis MA, Miles JM, et al. The Effect of Cognitive Behavioral Therapy for Insomnia in People with Type 2 Diabetes Mellitus, Pilot RCT Part II: Diabetes Health Outcomes. North Carolina: Research Square; 2020. https://doi.org/10.21203/rs.3.rs-25631/v4 DOI: https://doi.org/10.21203/rs.3.rs-25631/v4

Anothaisintawee T, Reutrakul S, van Cauter E, Thakkinstian A. Sleep disturbances compared to traditional risk factors for diabetes development: Systematic review and meta-analysis. Sleep Med Rev. 2016;30:11-24. https://doi.org/10.1016/j.smrv.2015.10.002 PMid:26687279 DOI: https://doi.org/10.1016/j.smrv.2015.10.002

Baoying H, Hongjie C, Changsheng Q, Peijian W, Qingfei L, Yinghua L, et al. Association of napping and nighttime sleep with impaired glucose regulation, insulin resistance and glycated hemoglobin in middle-aged Chinese adults with no diabetes: A cross-sectional study. BMJ Open. 2014;4(7):e004419. https://doi.org/10.1136/bmjopen-2013-004419 PMid:25056969 DOI: https://doi.org/10.1136/bmjopen-2013-004419

Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI. A cross sectional study of diet, physical activity, television viewing, and sleep duration in 233 110 adults from the UK Biobank; the behavioral phenotype of cardiovascular disease and Type 2 diabetes. BMJ Open. 2016;6(3):e010038. https://doi.org/10.1136/bmjopen-2015-010038 PMid:27008686 DOI: https://doi.org/10.1136/bmjopen-2015-010038

Chao CY, Wu JS, Yang YC, Shih CC, Wang RH, Lu FH, et al. Sleep duration is a potential risk factor for newly diagnosed Type 2 diabetes mellitus. Metabolism. 2011;60(6):799-804. https://doi.org/10.1016/j.metabol.2010.07.031 PMid:20846701 DOI: https://doi.org/10.1016/j.metabol.2010.07.031

Chasens ER, Luyster FS. Effect of sleep disturbances on quality of life, diabetes self-care behavior, and patient-reported outcomes. Diabetes Spectr. 2016;29(1):20-3. https://doi.org/10.2337/diaspect.29.1.20 PMid:26912961 DOI: https://doi.org/10.2337/diaspect.29.1.20

El-Aghoury AA, Elsherbiny TM, Lewis N, Salem TM, Osman N. Characterization of abnormal sleep patterns in patients with obesity, Type 2 diabetes, or combined. Alex J Med. 2018;54(4):455-62. https://doi.org/10.1016/j.ajme.2017.10.004 DOI: https://doi.org/10.1016/j.ajme.2017.10.004

Gupta S, Wang Z. Predictors of sleep disorders among patients with Type 2 diabetes mellitus. Diabetes Metab Syndr. 2016;10(4):213-20. https://doi.org/10.1016/j.dsx.2016.06.009 PMid:27377685 DOI: https://doi.org/10.1016/j.dsx.2016.06.009

Hu Y, Yan Z, Fu Z, Pan C. Associations of insomnia with hypertension and coronary artery disease among patients with Type 2 diabetes mellitus. Front Cardiovasc Med. 2021;8:730654. https://doi.org/10.3389/fcvm.2021.730654 PMid:34869629 DOI: https://doi.org/10.3389/fcvm.2021.730654

Jeon B, Sereika SM, Callan JA, Luyster FS, DiNardo MM, Chasens ER. Age-related differences in mood, diabetes related distress, and functional outcomes in adults with Type 2 diabetes mellitus and comorbid obstructive sleep apnea and insomnia. Diabetes Educ. 2020;46(6):540-51. https://doi.org/10.1177/0145721720958396 PMid:32948109 DOI: https://doi.org/10.1177/0145721720958396

Johann AF, Hertenstein E, Kyle SD, Baglioni C, Feige B, NissenC, et al. Insomnia with objective short sleep duration is associated with longer duration of insomnia in the Freiburg Insomnia Cohort compared to insomnia with normal sleep duration, but not with hypertension. PLoS One. 2017;12(7):e0180339. https://doi.org/10.1371/journal.pone.0180339 PMid:28746413 DOI: https://doi.org/10.1371/journal.pone.0180339

Khandelwal D, Dutta D, Chittawar S, Kalra S. Sleep disorders in Type 2 diabetes. Indian J Endocrinol Metab. 2017;21(5):758-61. https://doi.org/10.4103/ijem.IJEM_156_17 PMid:28989888 DOI: https://doi.org/10.4103/ijem.IJEM_156_17

Keskin A, Ünalacak M, Bilge U, Yildiz P, Güler S, Selçuk EB, et al. Effects of sleep disorders on hemoglobin A1c levels in Type 2 diabetic patients. Chin Med J (Engl). 2015;128(24):3292-7. https://doi.org/10.4103/0366-6999.171415 PMid:26668142 DOI: https://doi.org/10.4103/0366-6999.171415

Koopman AD, Beulens JW, Dijkstra T, Pouwer F, Bremmer MA, van Straten A, et al. Prevalence of insomnia (symptoms) in T2D and association with metabolic parameters and glycemic control: Meta-analysis. J Clin Endocrinol Metab. 2020;105(3):614-43. https://doi.org/10.1210/clinem/dgz065 PMid:31603475 DOI: https://doi.org/10.1210/clinem/dgz065

Larcher S, Gauchez AS, Lablanche S, Pépin JL, Benhamou PY, Borel AL. Impact of sleep behavior on glycemic control in Type 1 diabetes: The role of social jetlag. Eur J Endocrinol. 2016;175(5):411- 9. https://doi.org/10.1530/EJE-16-0188 PMid:27530460 DOI: https://doi.org/10.1530/EJE-16-0188

Makino S, Hirose S, Kakutani M, Fujiwara M, Nishiyama M, Terada Y, et al. Association between nighttime sleep duration, midday naps, and glycemic levels in Japanese patients with Type 2 diabetes. Sleep Med. 2018;44:4-11. https://doi.org/10.1016/j.sleep.2017.11.1124 PMid:29530368 DOI: https://doi.org/10.1016/j.sleep.2017.11.1124

Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Utzschneider KM, Nadeau KJ, et al. Association of self-reported sleep and circadian measures with glycemia in adults with prediabetes or recently diagnosed untreated Type 2 diabetes. Diabetes Care. 2019;42(7):1326-32. https://doi.org/10.2337/dc19-0298 PMid:31048411 DOI: https://doi.org/10.2337/dc19-0298

Mosavat M, Mirsanjari M, Arabia D, Smyth A, Whitehead L. The role of sleep curtailment on Leptin levels in obesity and diabetes mellitus. Obes Facts. 2021;14(2):214-21. https://doi.org/10.1159/000514095 PMid:33756469 DOI: https://doi.org/10.1159/000514095

Ohkuma T, Fujii H, Iwase M, Kikuchi Y, Ogata S, Iwaki Y, et al. Impact of sleep duration on obesity and the glycemic level in patients with Type 2 diabetes: The Fukuoka Diabetes Registry. Diabetes Care. 2013;36(3):611-7. https://doi.org/10.2337/dc12-0904 PMid:23150286 DOI: https://doi.org/10.2337/dc12-0904

Reutrakul S, Van Cauter E. Interactions between sleep, circadian function, and glucose metabolism: Implications for risk and severity of Diabetes: Sleep, circadian rhythms, and Diabetes. Ann N Y Acad Sci. 2014;1311(1):151-73. https://doi.org/10.1111/nyas.12355 PMid:24628249 DOI: https://doi.org/10.1111/nyas.12355

Reutrakul S, Zaidi N, Wroblewski K, Kay HH, Ismail M, Ehrmann DA, et al. Interactions between pregnancy, obstructive sleep apnea, and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013;98(10):4195-202. https://doi.org/10.1210/jc.2013-2348 PMid:23966237 DOI: https://doi.org/10.1210/jc.2013-2348

Schupp M, Hanning CD. Physiology of sleep. BJA CEPD Rev. 2003;3(3):69-74. https://doi.org/10.1093/bjacepd/mkg069 DOI: https://doi.org/10.1093/bjacepd/mkg069

Takahashi K. Relationship between Factors of Self-Care Ability in Adults with Diabetes and QOL; 2021. https://doi.org/10.26226/morressier.617c37307c09fc044a975118 DOI: https://doi.org/10.26226/morressier.617c37307c09fc044a975118

Thongsai S, Watanabenjasopa S, Youjaiyen M. Depression in patients with Type II diabetes: A case study at a diabetic outpatient clinic in Samut Prakan. Glob J Health Sci. 2013;6(1):127-34. https://doi.org/10.5539/gjhs.v6n1p127 PMid:24373272 DOI: https://doi.org/10.5539/gjhs.v6n1p127

Walker M. Why We Sleep: Unlocking the Power of Sleep and Dreams. United States: Simon and Schuster; 2017.

Whitaker KM, Lutsey PL, Ogilvie RP, Pankow JS, Bertoni A, Michos ED, et al. Associations between polysomnography and actigraphy-based sleep indices and glycemic control among those with and without Type 2 diabetes: The Multi-Ethnic Study of Atherosclerosis. Sleep. 2018;41(11):zsy172. https://doi.org/10.1093/sleep/zsy172 PMid:30184232 DOI: https://doi.org/10.1093/sleep/zsy172

Yoda K, Inaba M, Hamamoto K, Yoda M, Tsuda A, Mori K, et al. Association between poor glycemic control, impaired sleep quality, and increased arterial thickening in Type 2 diabetic patients. PLoS One. 2015;10(4):e0122521. https://doi.org/10.1371/journal.pone.0122521 PMid:25875738 DOI: https://doi.org/10.1371/journal.pone.0122521

Zhang P, Lou P, Chang G, Chen P, Zhang L, Li T, et al. Combined effects of sleep quality and depression on quality of life in patients with Type 2 diabetes. BMC Fam Pract. 2016;17(1):40. https://doi.org/10.1186/s12875-016-0435-x PMid:27044393 DOI: https://doi.org/10.1186/s12875-016-0435-x

Zhu B, Hershberger PE, Kapella MC, Fritschi C. The relationship between sleep disturbance and glycaemic control in adults with Type 2 diabetes: An integrative review. J Clin Nurs. 2017;26(23-4):4053-64. https://doi.org/10.1111/jocn.13899 PMid:28544107 DOI: https://doi.org/10.1111/jocn.13899

Zhu B, Quinn L, Kapella MC, Bronas UG, Collins EG, Ruggiero L, et al. Relationship between sleep disturbance and self-care in adults with Type 2 diabetes. Acta Diabetol. 2018;55(9):963-70. https://doi.org/10.1007/s00592-018-1181-4 PMid:29931420 DOI: https://doi.org/10.1007/s00592-018-1181-4

McLain JM, Alami WH, Slovak ZT, Cooley CR, Burke SJ, Collier JJ, et al. Sleep fragmentation delays wound healing in a mouse model of Type 2 diabetes. Sleep. 2018;41(11): Available from: zsy156. https://doi.org/10.1093/sleep/zsy156 PMid:30107617 DOI: https://doi.org/10.1093/sleep/zsy156

Leproult R, Holmbäck U, Van Cauter E. Circadian misalignment augments insulin resistance and inflammation markers, independent of sleep loss. Diabetes. 2014;63(6):1860-9. https://doi.org/10.2337/db13-1546 PMid:24458353 DOI: https://doi.org/10.2337/db13-1546

Bromley LE, Booth JN 3rd, Kilkus JM, Imperial JG, Penev PD. Sleep restriction decreases adults’ physical activity and at risk for Type 2 diabetes. Sleep. 2012;35(7):977-84. https://doi.org/10.5665/sleep.1964 PMid:22754044 DOI: https://doi.org/10.5665/sleep.1964

How Does Sleep Affect Your Cholesterol Levels? Available from: https://www.webmd.com/cholesterol-management/how-sleep-affects-cholesterol [Last accessed on 2022 Mar 04].

Arble DM, Ramsey KM, Bass J, Turek FW. Circadian disruption and metabolic disease: Findings from animal models. Best Pract Res Clin Endocrinol Metab. 2010;24:785-800. https:/doi.org/10.1016/j.beem.2010.08.003 PMid:21112026 DOI: https://doi.org/10.1016/j.beem.2010.08.003

Huang W, Ramsey KM, Marcheva B, Bass J. Circadian rhythms, sleep, and metabolism. J Clin Invest. 2011;121(6):2133-41. https://doi.org/10.1172/JCI46043 PMid:21633182 DOI: https://doi.org/10.1172/JCI46043

Espie CA, Emsley R, Kyle SD, Gordon C, Drake CL, Siriwardena AN, et al. Effect of digital cognitive behavioral therapy for insomnia on health, psychological well-being, and sleep-related quality of life: A randomized clinical trial. JAMA Psychiatry. 2019;76(1):21-30. https://doi.org/10.1001/jamapsychiatry.2018.2745 PMid:30264137 DOI: https://doi.org/10.1001/jamapsychiatry.2018.2745

Kalam F, Gabel K, Cienfuegos S, Ezpeleta M, Wiseman E, Varady KA. Alternate day fasting combined with a low carbohydrate diet: Effect on sleep quality, duration, insomnia severity, and risk of obstructive sleep apnea in adults with obesity. Nutrients. 2021;13(1):211. https://doi.org/10.3390/nu13010211 PMid:33450908 DOI: https://doi.org/10.3390/nu13010211

Stein N. Sleep, Hormones, and Health: Why Sleep Feels So Good and Is So Good for You Lark Health. Lark; 2020. Available from: https://www.lark.com/blog/sleep-hormones-and-health [Last accessed on 2022 Mar 04].

Soltani M, Haytabakhsh MR, Najman JM, Williams GM, O’Callaghan MJ, Bor W, et al. Sleepless nights: The effect of socioeconomic status, physical activity, and lifestyle factors on sleep quality in a large cohort of Australian women. Arch Women’s Ment Health. 2012;15(4):237-47. https://doi.org/10.1007/s00737-012-0281-3 PMid:22585289 DOI: https://doi.org/10.1007/s00737-012-0281-3

Surani S, Brito V, Surani A, Ghamande S. Effect of diabetes mellitus on sleep quality. World J Diabetes. 2015;6(6):868-73. https://doi.org/10.4239/wjd.v6.i6.868 PMid:26131327 DOI: https://doi.org/10.4239/wjd.v6.i6.868

Reutrakul S, Hood MM, Crowley SJ, Morgan MK, Teodori M, Knutson KL, et al. Chronotype is independently associated with glycemic control in Type 2 diabetes. Diabetes Care. 2013;36(9):2523-9. https://doi.org/10.2337/dc12-2697 PMid:23637357 DOI: https://doi.org/10.2337/dc12-2697

Alshehri MM, Alkathiry AA, Alenazi AM, Alothman SA, Rucker JL, Phadnis MA, et al. sleep efficiency and total sleep time in individuals with Type 2 diabetes with and without insomnia symptoms. Sleep Disord. 2020;2020:5950375. https://doi.org/10.1155/2020/5950375 PMid:32724680 DOI: https://doi.org/10.1155/2020/5950375

Mason IC, Qian J, Adler GK, Scheer FA. Impact of circadian disruption on glucose metabolism: Implications for Type 2 diabetes. Diabetologia. 2020;63(3):462-72. https://doi.org/10.1007/s00125-019-05059-6 PMid:31915891 DOI: https://doi.org/10.1007/s00125-019-05059-6

Garfinkel D, Zorin M, Wainstein J, Matas Z, Laudon M, Zisapel N. Efficacy and safety of prolonged-release melatonin in insomnia patients with Diabetes: A randomized, double-blind, crossover study. Diabetes Metab Syndr Obes. 2011;4:307-13. https://doi.org/10.2147/DMSO.S23904 PMid:21887103 DOI: https://doi.org/10.2147/DMSO.S23904

Chasens ER, Korytkowski M, Sereika SM, Burke LE. Effect of poor sleep quality and excessive daytime sleepiness on factors associated with diabetes self-management. Diabetes Educ. 2013;39(1):74-82. https://doi.org/10.1177/0145721712467683 PMid:23192600 DOI: https://doi.org/10.1177/0145721712467683

Jain SK, Kahlon G, Morehead L, Lieblong B, Stapleton T, Hoeldtke R, et al. The effect of sleep apnea and insomnia on blood levels of leptin, insulin resistance, IP-10, and hydrogen sulfide in Type 2 diabetic patients. Metab Syndr Relat Disord. 2012;10(5):331-6. https://doi.org/10.1089/met.2012.0045 PMid:22746298 DOI: https://doi.org/10.1089/met.2012.0045

Arora T, Taheri S. Sleep optimization and diabetes control: A literature review. Diabetes Ther. 2015;6(4):425-68. https://doi.org/10.1007/s13300-015-0141-z PMid:26537705 DOI: https://doi.org/10.1007/s13300-015-0141-z

Larcher S, Benhamou PY, Pépin JL, Borel AL. Sleep habits and diabetes. Diabetes Metab. 2015;41(4):263-71. https://doi.org/10.1016/j.diabet.2014.12.004 PMid:25623152 DOI: https://doi.org/10.1016/j.diabet.2014.12.004

Zhu B, Vincent C, Kapella MC, Quinn L, Collins EG, Ruggiero L, et al. Sleep disturbance in people with diabetes: A concept analysis. J Clin Nurs. 2018;27(1-2):e50-60. https://doi.org/10.1111/jocn.14010 PMid:28793386 DOI: https://doi.org/10.1111/jocn.14010

Garbarino S, Lanteri P, Bragazzi NL, Magnavita N, Scoditti E. Role of sleep deprivation in immune-related disease risk and outcomes. Commun Biol. 2021;4(1):1304. https://doi.org/10.1038/s42003-021-02825-4 PMid:34795404 DOI: https://doi.org/10.1038/s42003-021-02825-4

Karamitri A, Jockers R. Melatonin in Type 2 diabetes mellitus and obesity. Nat Rev Endocrinol. 2019;15(2):105-25. https://doi.org/10.1038/s41574-018-0130-1 PMid:30531911 DOI: https://doi.org/10.1038/s41574-018-0130-1

Tsai YW, Kann NH, Tung TH, Chao YJ, Lin CJ, Chang KC, et al. Impact of subjective sleep quality on glycemic control in Type 2 diabetes mellitus. Fam Pract. 2012;29(1):30-5. https://doi.org/10.1093/fampra/cmr041 PMid:21795758 DOI: https://doi.org/10.1093/fampra/cmr041

Al-Abri MA, Jaju D, Al-Sinani S, Al-Mamari A, Albarwani S, Al-Resadi K, et al. Habitual sleep deprivation is associated with Type 2 diabetes: A case-control study. Oman Med J. 2016;31(6):399-403. https://doi.org/10.5001/omj.2016.81 PMid:27974953 DOI: https://doi.org/10.5001/omj.2016.81

Diabetes. Available from: https://www.who.int/news-room/fact sheets/detail/diabetes [Last accessed on 2022 Mar 04].

Facts and Figures. Available from: https://www.idf.org/ aboutdiabetes/what-is-diabetes/facts-figures.html [Last accessed on 2022 Mar 04].

Luyster FS, Dunbar-Jacob J. Sleep quality and quality of life in adults with Type 2 diabetes. Diabetes Educ. 2011;37(3):347-55. https://doi.org/10.1177/0145721711400663 PMid:21467248 DOI: https://doi.org/10.1177/0145721711400663

Pereira FH, Trevisan DD, Lourenço DS, da Silva JB, Lima MH. Effect of educational strategies on the sleep quality of people with diabetes: Randomized clinical trial. Aquichan. 2019;19(3):1-13. https://doi.org/10.5294/aqui.2019.19.3.2 DOI: https://doi.org/10.5294/aqui.2019.19.3.2

Khalil M, Power N, Graham E, Deschênes SS, Schmitz N. The association between sleep and diabetes outcomes--a systematic review. Diabetes Res Clin Pract. 2020;161:108035. https://doi.org/10.1016/j.diabres.2020.108035 PMid:32006640 DOI: https://doi.org/10.1016/j.diabres.2020.108035

Narisawa H, Komada Y, Miwa T, Shikuma J, Sakurai M, Odawara M, et al. Prevalence, symptomatic features, and factors associated with sleep disturbance/insomnia in Japanese patients with Type-2 Diabetes. Neuropsychiatr Dis Treat. 2017;13:1873-80. https://doi.org/10.2147/NDT.S134814 PMid:28765709 DOI: https://doi.org/10.2147/NDT.S134814

JIB Global; 2013. Available from: https://JBI.global/sites/ default/files/2019-05/JBI-Levels-of-evidence_2014_0pdf [Last accessed on 2022 Mar 14].

Tannas CL. Type 2 Diabetes and Insomnia: Impact on Metabolic Control. United States: Wayne State University; 2012.

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2023-01-01

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Woods NP, Tangpukdee J, Thepa T, Methakanchanasak N. Consequences of Sleep Deprivation in Adult Diabetes Mellitus Type 2 Patients: An Integrative Review. Open Access Maced J Med Sci [Internet]. 2023 Jan. 1 [cited 2024 Apr. 26];11(F):1-10. Available from: https://oamjms.eu/index.php/mjms/article/view/10029

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