Neuroprotective Agents: A Simple Overview

Ageng Sunjoyo; Andy Nugroho

doi:10.3889/oamjms.2022.10329

Authors

Ageng Sunjoyo Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sebelas Maret, Dr. Moewardi Hospital, Surakarta, Indonesia
Andy Nugroho Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sebelas Maret, Dr. Moewardi Hospital, Surakarta, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.10329

Keywords:

Anaesthetic care, Critical illness, ICU, Neuroprotection, Neuroprotective agent

Abstract

Neuroprotective agents are medications that can alter the course of metabolic events and have neuroprotective function. Neuroprotective agents are needed in patients undergoing a surgical procedure and clinical conditions that correspond with the central nervous system (CNS); also, in intensive care, the neuroprotective agents are often used to prevent complications and patient deterioration. Over the years, there is still no clear understanding of the potential for neuroprotection and the interactions between various drugs that serve a crucial role in anesthetic care and critical illness. This literature review will discuss further the mechanism of neuronal damage and various neuroprotective agents.

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