Discovering the Relationship between Anxiety or Depression and Risk Factors of Coronary Artery Disease

Authors

  • Badai Bhatara Tiksnadi Department of Cardiology and Vascular Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia https://orcid.org/0000-0002-0314-5577
  • Cindya Perthy Iswandi Department of Cardiology and Vascular Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia https://orcid.org/0000-0002-4285-7809
  • Transiska Liesmadona Bijaksana Department of Cardiology and Vascular Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia https://orcid.org/0000-0002-5347-8265
  • Nicolaus Novian Dwiya Wahjoepramono Department of Cardiology and Vascular Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2023.10832

Keywords:

CAD, anxiety, depression, risk factors

Abstract

BACKGROUND: Psychosocial problems, including anxiety or depression, potentially activate several mechanisms that affect coronary artery disease (CAD) cardiovascular risk factors. Their clinical association, however, remains undiscovered.

AIM: The objective of this study was to discover the association between the prevalence of anxiety or depression and risk factors of CAD.

METHODS: A cross-sectional study was conducted from July to October 2019. Subject population was CAD patients hospitalized in the Cardiac Care Unit at Hasan Sadikin General Hospital Bandung. We included patients with a history of CAD who underwent revascularization and filled the Hospital Anxiety and Depression Scale (HADS) questionnaire before discharge. Patients were classified according to normal (HADS score of 0–7) or abnormal levels of anxiety or depression (HADS score of 8–21). From each patient, we obtained information on risk factors of CAD, including smoking, physical inactivity, dyslipidemia, hypertension, diabetes mellitus (DM), and family history of CAD.

RESULTS: Ninety-nine CAD patients (79% male, mean age: 59 ± 10.5 years) were included in the study; 40% were smokers, 60% had physical inactivity, 11% had dyslipidemia, 57% had hypertension, 13% had DM, 7% had a family history of CAD, and 23% subjects had abnormal levels of anxiety or depression. The relationship between anxiety or depression in CAD patients and smoking behavior (p = 0.802), family history of CAD (p = 0.563), dyslipidemia (p = 0.738), hypertension (p = 0.283), and DM (p = 0.403) was not statistically significant.

CONCLUSIONS: The present study showed that the prevalence of anxiety or depression in CAD patients was relatively moderate. We revealed that psychosocial factors are not associated with risk factors of CAD, stressing that psychosocial factors are independent of conventional CAD risk factors in CAD and merit attention for individual management.

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References

Eng HS, Yean LC, Das S, Letchmi S, Yee KS, Bakar RA, et al. Anxiety and depression in patients with coronary heart disease: A study in a tertiary hospital. Iran J Med Sci. 2011;36(3):201-6. PMid:23358115

Murphy B, Le Grande M, Alvarenga M, Worcester M, Jackson A. Anxiety and depression after a cardiac event: Prevalence and predictors. Front Psychol. 2020;10:3010. https://doi.org/10.3389/fpsyg.2019.03010 PMid:32063868 DOI: https://doi.org/10.3389/fpsyg.2019.03010

Brydon L, Magid K, Steptoe A. Platelets, coronary heart disease, and stress. Brain Behav Immun. 2006;20(2):113-9. https://doi.org/10.1016/j.bbi.2005.08.002 PMid:16183245 DOI: https://doi.org/10.1016/j.bbi.2005.08.002

Cuevas AG, Williams DR, Albert MA. Psychosocial factors and hypertension: A review of the literature. Cardiol Clin. 2017;35(2):223-30. https://doi.org/10.1016/j.ccl.2016.12.004 PMid:28411896 DOI: https://doi.org/10.1016/j.ccl.2016.12.004

Brotman DJ, Golden SH, Wittstein IS. The cardiovascular toll of stress. Lancet. 2007;370(9592):1089-100. https://doi.org/10.1016/S0140-6736(07)61305-1 PMid:17822755 DOI: https://doi.org/10.1016/S0140-6736(07)61305-1

Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361-70. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x PMid:6880820 DOI: https://doi.org/10.1111/j.1600-0447.1983.tb09716.x

Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the hospital anxiety and depression scale: An updated literature review. J Psychosom Res. 2002;52(2):69-77. https://doi.org/10.1016/s0022-3999(01)00296-3 PMid:11832252 DOI: https://doi.org/10.1016/S0022-3999(01)00296-3

Rozanski A, Blumenthal JA, Kaplan J. Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation. 1999;99(16):2192-217. https://doi.org/10.1161/01.cir.99.16.2192 PMid:10217662 DOI: https://doi.org/10.1161/01.CIR.99.16.2192

Dixon T, Lim LL, Powell H, Fisher JD. Psychosocial experiences of cardiac patients in early recovery: A community based study. J Adv Nurs. 2000;31(6):1368-75. https://doi.org/10.1046/j.1365-2648.2000.01406.x PMid:10849148 DOI: https://doi.org/10.1046/j.1365-2648.2000.01406.x

Deo P, Istiqomah AN, Pandia V, Lidyana L, Tiksnadi BB, Andayani S. Correlation of depression and illness cognition in coronary artery disease at Hasan Sadikin Hospital Bandung, Java, Indonesia. Mal J Med Health Sci. 2022;18(1):121-8.

Visseren FL, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European society of cardiology and 12 medical societies with the special contribution of the European association of preventive cardiology (EAPC). Eur Heart J. 2021;42(34):3227-337. https://doi.org/10.1093/eurheartj/ehab484 PMid:34458905 DOI: https://doi.org/10.1093/eurheartj/ehab484

Kim JM, Stewart R, Kang HJ, Kim SY, Kim JW, Lee HJ, et al. Long-term cardiac outcomes of depression screening, diagnosis and treatment in patients with acute coronary syndrome: The DEPACS study. Psychol Med. 2021;51(6):964-74. https://doi.org/10.1017/S003329171900388X PMid:31907104 DOI: https://doi.org/10.1017/S003329171900388X

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Published

2023-01-01

How to Cite

1.
Tiksnadi BB, Iswandi CP, Bijaksana TL, Wahjoepramono NND. Discovering the Relationship between Anxiety or Depression and Risk Factors of Coronary Artery Disease. Open Access Maced J Med Sci [Internet]. 2023 Jan. 1 [cited 2024 Nov. 24];11(B):5-8. Available from: https://oamjms.eu/index.php/mjms/article/view/10832

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