The Relation between Mean Platelets Volume and Obesity among patients in the Primary Health-care Centers at National Guard in Jeddah, Saudi Arabia
DOI:
https://doi.org/10.3889/oamjms.2023.11308Keywords:
Mean platelets volume, Body mass index, ObesityAbstract
BACKGROUND: Obesity is excess and fat accumulation that lead to negative effects on health. Many studies found an association between obesity and MPV. MPV is a determinant of platelet function, since platelet size has been proven to reflect platelet activity, which is an useful predictive biomarker for a variety of diseases. This is the second study in which MPV was evaluated in obese patients in KSA.
AIM: The aim of study is to evaluate the relation between MPV and obese patients without metabolic risk factors at NGHA Jeddah, KSA. Secondary objectives are to compare between genders and to evaluate the association between total platelets count and obesity.
METHODS: This was a cross-sectional study, A. Inclusion criteria: For the first group, any patient with BMI ≥ than 30 kg/m2 aged 18 years or more. Second group, non-obese aged 18 years or more. Exclusion criteria: Metabolic risk.
RESULTS: There were 279 participated in this study. Most of the participants 214 (72.1%) were females, and 83 (27.9%) were males (Table 1). The mean age was 33.39 ± 10.19. There were 148 (49.8%) participants with normal BMI level, and 149 (50.2%) considered as obese. For MPV classification, 287 (96.6%) were normal, and 10 (3.4%) were high. In this case–control study, we found no significant evidence relating the association between MPV and obesity.
CONCLUSION: In this study, we found no significant difference between MPV and platelet count between them. However, there was a significant positive week correlation between BMI and age with p = 0.0001.Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Obesity World Health Organization. Available from: https://www.who.int/health-topics/obesity#tab=tab_1 [Last accessed on 2021 Apr 20].
Al-Nuaim AA, Bamgboye EA, Al-Rubeaan KA, Al-Mazrou Y. Overweight and obesity in Saudi Arabian adult population, role of socio-demographic variables. J Community Health. 1997;22(3):211-23. https://doi.org/10.1023/a:1025177108996 PMid:9178120 DOI: https://doi.org/10.1023/A:1025177108996
World Health Organization. Stepwise Approach to NCD Surveillance. Country Specific Standard Report, Saudi Arabia 2004. Riyadh: Ministry of Health, Saudi Arabia, and World Health Organization; 2005. Available from: https://cdn.who.int/media/docs/default-source/ncds/ncd-surveillance/data-reporting/saudi-arabia/steps/2005-saudiarabia-steps-report-en.pdf?sfvrsn=a5bdced3_2&download=true [Last accessed on 2022 May 25].
Al-Quwaidhi AJ, Pearce MS, Critchley JA, Sobngwi E, O’Flaherty M. Trends and future projections of the prevalence of adult obesity in Saudi Arabia, 1992-2022. East Mediterr Health J. 2014;20(10):589-95. PMid:25356689 DOI: https://doi.org/10.26719/2014.20.10.589
Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: A link between thrombosis and inflammation? Curr Pharm Des. 2011;17(1):47-58. https://doi.org/10.2174/138161211795049804 PMid:21247392 DOI: https://doi.org/10.2174/138161211795049804
Korniluk A, Koper-Lenkiewicz OM, Kamińska J, Kemona H, Dymicka-Piekarska V. Mean Platelet Volume (MPV): New Perspectives for an old marker in the course and prognosis of inflammatory conditions. Mediators Inflamm. 2019;2019:9213074. https://doi.org/10.1155/2019/9213074 PMid:31148950 DOI: https://doi.org/10.1155/2019/9213074
Coban E, Ozdogan M, Yazicioglu G, Akcit F. The mean platelet volume in patients with obesity. Int J Clin Pract. 2005;59(8):981-2. https://doi.org/10.1111/j.1742-1241.2005.00500.x PMid:16033624 DOI: https://doi.org/10.1111/j.1742-1241.2005.00500.x
Furman-Niedziejko A, Rostoff P, Rychlak R, Golinska- Grzybala K, Wilczynska-Golonka M, Golonka M, et al. Relationship between abdominal obesity, platelet blood count and mean platelet volume in patients with metabolic syndrome. Folia Med Cracov. 2014;54(2):55-64. PMid:25648310
Aktas G, Kocak MZ, Duman TT, Erkus E, Atak BM, Sit M, et al. Mean platelet volume (MPV) as an inflammatory marker in Type 2 diabetes mellitus and obesity. Bali Med J. 2018;7(3):650-3. https://doi.org/10.15562/bmj.v7i3.806 DOI: https://doi.org/10.15562/bmj.v7i3.806
Coban E, Yilmaz A, Sari R. The effect of weight loss on the mean platelet volume in obese patients. Platelets. 2007;18(3):212-6. https://doi.org/10.1080/09537100600975362 PMid:17497433 DOI: https://doi.org/10.1080/09537100600975362
Pinto RV, Rodrigues G, Simões RL, Porto LC. Analysis of post-sample collection EDTA effects on mean platelet volume values in relation to overweight and obese patient status. Acta Haematol. 2019;142(3):149-53. https://doi.org/10.1159/000499101 PMid:31189163 DOI: https://doi.org/10.1159/000499101
Alshehri OM, Seoudi MA, Sahli KA, Elkhawanky MM. The platelet indices in patients with obesity in Najran Area, Saudi Arabia [abstract]. Res Pract Thromb Haemost. 2020;4(Suppl 1). Available From: https://abstracts.isth.org/abstract/the-platelet-indices-in-patients-with-obesity-in-najran-area-saudi-arabia/ [Last accessed on 2022 Jul 26].
Nkambule BB, Mxinwa V, Nyambuya TM, Dludla PV. The mean platelet volume and atherosclerotic cardiovascular-risk factors in adults with obesity: A systematic review and meta-analysis of observational studies BMC Nutr. 2022;8(1):47. https:///doi.org/10.1186/s40795-022-00541-8 PMid:35578358 DOI: https://doi.org/10.1186/s40795-022-00541-8
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2023 Abduallah Alzahrani, Yasmeen Alshehri, Nourah Alageel, Roaa Bakraa, Renad Rawas, Raghed Alwagdani (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
http://creativecommons.org/licenses/by-nc/4.0