Intima–Media Thickness in Primary Aldosteronism Compared with Essential Hypertension: A Meta-analysis

Eva Muja; Ilirian Laçi; Sonil Marko; Ilir Akshija

doi:10.3889/oamjms.2024.11594

Authors

Eva Muja Department of Cardiology, Catholic University “Our Lady of Good Counsel”, Tirana, Albania https://orcid.org/0000-0001-7507-6307
Ilirian Laçi Department of Radiology, Medical University of Tirana, Tirana, Albania https://orcid.org/0000-0001-9480-0065
Sonil Marko Department of Internal Medicine, Medical University of Tirana, Tirana, Albania
Ilir Akshija Department of Statistics, Medical University of Tirana, Tirana, Albania

DOI:

https://doi.org/10.3889/oamjms.2024.11594

Keywords:

essential hypertension, intima media, primary aldosteronism

Abstract

AIM: This study was comparison of the intima–media thickness in the primary aldosteronism (PA) patients versus essential hypertension (EH) patients.

METHODS: We searched on PubMed for studies about intima–media thickness in PA and found 317 articles. After the title and abstract reading, we excluded 291 studies because they did not fit in our criteria. After the final assessment of the 26 articles, seven of them were chosen as final studies to be included in the meta-analysis.

RESULTS: In this study, we included seven studies with a total of participants of 534 patients. The main outcome was a comparison of intima–media thickness between patients with PA, EHs and healthy controls. The result shows a thicker intima media in PA patients in comparison with EH patients and more over with healthy controls, but this was not statistically significant.

CONCLUSION: PA predisposes to a thicker intima media in comparison to EH, but we need for larger studies to have significant results.

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