Increased Nuchal Translucency in Fetuses with Normal Karyotype

Simona Anzhel; Emil  Kovachev; Zhivko Zhekov; Boyan Georgiev

doi:10.3889/oamjms.2024.11790

Authors

Simona Anzhel Department of Obstetrics and Gynecology, MU – Varna, Bulgaria; SBAGAL “Prof. Dr. Dimitar Stamatov,” Varna, Bulgaria https://orcid.org/0000-0002-6142-4451
Emil Kovachev Department of Obstetrics and Gynecology, MU – Varna, Bulgaria; SBAGAL “Prof. Dr. Dimitar Stamatov,” Varna, Bulgaria https://orcid.org/0000-0002-6142-4451
Zhivko Zhekov Department of Obstetrics and Gynecology, MU – Varna, Bulgaria; SBAGAL “Prof. Dr. Dimitar Stamatov,” Varna, Bulgaria
Boyan Georgiev Department of Obstetrics and Gynecology, MU – Varna, Bulgaria; SBAGAL “Prof. Dr. Dimitar Stamatov,” Varna, Bulgaria https://orcid.org/0000-0002-3912-1577

DOI:

https://doi.org/10.3889/oamjms.2024.11790

Keywords:

nuchal translucency, chromosomal abnormalities, karyotype, sIUGR

Abstract

BACKGROUND: Increased nuchal translucency (NT) is associated with a high risk of chromosomal abnormalities and genetic syndromes. In fetuses with normal karyotype, thickened NT increases the likelihood of congenital heart malformations, spontaneous abortions, and stillbirths, especially in thickness > 3.5 mm. It was found that in the absence of accompanying structural abnormalities and a normal result of amniocentesis, the postnatal neurological development of the newborns did not differ from the general population.

CASE PRESENTATION: The authors describe a case of sIUGR of monochorionic twins with second trimester selective umbilical cord ablation and livebirth of a healthy singleton.

CONCLUSION: Abnormal NT thickness on early fetal morphology scan in euploid fetuses, especially in twin pregnancies, increase the suspicion for late complications of the pregnancy.

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