The Hemostatic Effect of T-Hemocel in Neurosurgery Case
DOI:
https://doi.org/10.3889/oamjms.2024.11834Keywords:
Hemostatic, T-Hemocel, Oxidized regenerated cellulose, EfficacyAbstract
BACKGROUND: Decompressive craniectomy (DC) is a neurosurgical procedure associated with significant blood loss. Effective hemostatic agents can minimize blood loss and improve surgical outcomes. T- Hemocel, a hemostatic agent composed of oxidized regenerated cellulose, is increasingly used in neurosurgery, but its efficacy in DC requires further investigation.
AIM: This study aimed to evaluate the hemostatic efficacy of T-Hemocel in patients undergoing DC.
METHODS: A retrospective chart review was conducted on ten (10) patients who underwent DC at our institution between July 2019 and August 2019. Data on patient demographics, time to hemostasis, and surgical complications were collected. Due to the limited sample size, a control group receiving a different hemostatic agent was not included.
RESULTS: All ten patients who received T-Hemocel during DC achieved hemostasis within 10 min of administration. No surgical bleeding incidents were reported. This retrospective analysis suggests that T-Hemocel may be a viable hemostatic option in DC, with all patients achieving hemostasis within 10 min. However, the small sample size limits the generalizability of these findings.
CONCLUSION: Future studies with larger sample sizes and potentially including a control group are warranted to confirm these observations and explore the efficacy of T-Hemocel in a broader range of neurosurgical procedures.
Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Tackett SM, Sugarman R, Kreuwel HT, Alvarez P, Nasso G. Hospital economic impact from hemostatic matrix usage in cardiac surgery. J Med Econ. 2014;17(9):670-6. https://doi.org/10.3111/13696998.2014.928638 PMid:24927164 DOI: https://doi.org/10.3111/13696998.2014.928638
Anis SB, Khan SA, Mitha R, Shamim MS. Craniotomy or craniectomy for acute subdural hematoma? Difference in patient characteristics and outcomes at a tertiary care hospital. Asian J Neurosurg. 2022;17(4):563-7. https://doi.org/10.1055/s-0042-1758842 PMid:36570762 DOI: https://doi.org/10.1055/s-0042-1758842
Shaltout MF, Elsheikhah A, Maged AM, Elsherbini MM, Zaki SS, Dahab S, et al. A randomized controlled trial of a new technique for laparoscopic management of ovarian endometriosis preventing recurrence and keeping ovarian reserve. J Ovarian Res. 2019;12(1):66. https://doi.org/10.1186/s13048-019-0542-0 PMid:31325962 DOI: https://doi.org/10.1186/s13048-019-0542-0
Wang C, Han Z, Zhang T, Ma JX, Jiang X, Wang Y, et al. The efficacy of a thrombin-based hemostatic agent in primary total knee arthroplasty: A meta-analysis. J Orthop Surg Res. 2014;9:90. https://doi.org/10.1186/s13018-014-0090-7 PMid:25316253 DOI: https://doi.org/10.1186/s13018-014-0090-7
Sobani ZA, Shamim MS, Zafar SN, Qadeer M, Bilal N, Murtaza SG, et al. Cranioplasty after decompressive craniectomy: An institutional audit and analysis of factors related to complications. Surg Neurol Int. 2011;2(1):123. https://doi.org/10.4103/2152-7806.85055 PMid:22059118 DOI: https://doi.org/10.4103/2152-7806.85055
Wagenhäuser MU, Mulorz J, Ibing W, Simon F, Spin JM, Schelzig H, et al. Oxidized (non)-regenerated cellulose affects fundamental cellular processes of wound healing. Sci Rep. 2016;6:32238. https://doi.org/10.1038/srep32238 PMid:27557881 DOI: https://doi.org/10.1038/srep32238
Qian Z, Xiong F, Xia X, Gu P, Wang Q, Wu A, et al. Clinical and economic impact of oxidized regenerated cellulose for surgeries in a Chinese tertiary care hospital. J Comp Eff Res. 2020;9(15):1079-90. https://doi.org/10.2217/cer-2020-0166 PMid:32959666 DOI: https://doi.org/10.2217/cer-2020-0166
Slezak P, Keibl C, Labahn D, Schmidbauer A, Genyk Y, Gulle H. A comparative efficacy evaluation of recombinant topical thrombin (RECOTHROM®) with a gelatin sponge carrier versus topical oxidized regenerated cellulose (TABOTAMP®/ SURGICEL®) in a porcine liver bleeding model. J Invest Surg. 2021;34(8):862-8. https://doi.org/10.1080/08941939. 2019.1705444 PMid:31955627 DOI: https://doi.org/10.1080/08941939.2019.1705444
Sitohang D, Am R, Arif M. I 143 Estimated Blood Loss in Craniotomy. Available from: https://www.mayfieldclinic.com [Last accessed on 2024 May 06].
Shirakawa T, Yokoi K, Seya T, Yoshioka M, Ohaki Y, Uchida E. A case of extra-hepatic bill duct wall recurrence of gastric carcinoma that was treated with pancreaticoduodenectomy. J Nippon Med Sch. 2010;77(3):170-4. https://doi.org/10.1272/jnms.77.170 PMid:20610902 DOI: https://doi.org/10.1272/jnms.77.170
Tam T, Harkins G, Dykes T, Gockley A, Davies M. Oxidized regenerated cellulose resembling vaginal cuff abscess. JSLS. 2014;18(2):353-6. https://doi.org/10.4293/108680813X13693422518597 PMid:24960506 DOI: https://doi.org/10.4293/108680813X13693422518597
Weaver CS, Leonardi-Bee J, Bath-Hextall FJ, Bath PM. Sample size calculations in acute stroke trials: A systematic review of their reporting, characteristics, and relationship with outcome. Stroke. 2004;35(5):1216-24. https://doi.org/10.1161/01.STR.0000125010.70652.93 PMid:1503145 DOI: https://doi.org/10.1161/01.STR.0000125010.70652.93
Downloads
Published
How to Cite
License
Copyright (c) 2024 Andi Asadul Islam, Juliani Ibrahim, Venansius R. Kurniawan (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
http://creativecommons.org/licenses/by-nc/4.0